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Items: 1 to 20 of 152

1.

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1.

Prins KC, Cárdenas WB, Basler CF.

J Virol. 2009 Apr;83(7):3069-77. doi: 10.1128/JVI.01875-08. Epub 2009 Jan 19.

2.

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.

Cárdenas WB, Loo YM, Gale M Jr, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF.

J Virol. 2006 Jun;80(11):5168-78.

3.

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A.

J Virol. 2003 Jul;77(14):7945-56.

4.

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.

Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):17-28.

PMID:
16914100
5.

Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.

Civas A, Génin P, Morin P, Lin R, Hiscott J.

J Biol Chem. 2006 Feb 24;281(8):4856-66. Epub 2005 Dec 27.

6.

Evasion of interferon responses by Ebola and Marburg viruses.

Basler CF, Amarasinghe GK.

J Interferon Cytokine Res. 2009 Sep;29(9):511-20. doi: 10.1089/jir.2009.0076. Review.

7.

Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.

Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20661-6. doi: 10.1073/pnas.1213559109. Epub 2012 Nov 26.

8.

Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε.

Pythoud C, Rodrigo WW, Pasqual G, Rothenberger S, Martínez-Sobrido L, de la Torre JC, Kunz S.

J Virol. 2012 Aug;86(15):7728-38. doi: 10.1128/JVI.00187-12. Epub 2012 Apr 24.

9.

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.

Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J, Meurs EF.

J Virol. 2005 Apr;79(7):3969-78.

10.

Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation.

Yen B, Mulder LC, Martinez O, Basler CF.

J Virol. 2014 Nov;88(21):12500-10. doi: 10.1128/JVI.02163-14. Epub 2014 Aug 20.

11.

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets.

Yang Y, Ye F, Zhu N, Wang W, Deng Y, Zhao Z, Tan W.

Sci Rep. 2015 Dec 3;5:17554. doi: 10.1038/srep17554.

12.

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.

tenOever BR, Sharma S, Zou W, Sun Q, Grandvaux N, Julkunen I, Hemmi H, Yamamoto M, Akira S, Yeh WC, Lin R, Hiscott J.

J Virol. 2004 Oct;78(19):10636-49.

14.

SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways.

Huang J, Liu T, Xu LG, Chen D, Zhai Z, Shu HB.

EMBO J. 2005 Dec 7;24(23):4018-28. Epub 2005 Nov 10.

15.

Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages.

Solis M, Romieu-Mourez R, Goubau D, Grandvaux N, Mesplede T, Julkunen I, Nardin A, Salcedo M, Hiscott J.

Eur J Immunol. 2007 Feb;37(2):528-39.

16.

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation.

Schröder M, Baran M, Bowie AG.

EMBO J. 2008 Aug 6;27(15):2147-57. doi: 10.1038/emboj.2008.143. Epub 2008 Jul 17.

17.
18.

Peripheral B cells may serve as a reservoir for persistent hepatitis C virus infection.

Ito M, Masumi A, Mochida K, Kukihara H, Moriishi K, Matsuura Y, Yamaguchi K, Mizuochi T.

J Innate Immun. 2010;2(6):607-17. doi: 10.1159/000317690. Epub 2010 Aug 17.

19.

Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.

Unterholzner L, Sumner RP, Baran M, Ren H, Mansur DS, Bourke NM, Randow F, Smith GL, Bowie AG.

PLoS Pathog. 2011 Sep;7(9):e1002247. doi: 10.1371/journal.ppat.1002247. Epub 2011 Sep 8.

20.

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter.

Paz S, Vilasco M, Arguello M, Sun Q, Lacoste J, Nguyen TL, Zhao T, Shestakova EA, Zaari S, Bibeau-Poirier A, Servant MJ, Lin R, Meurs EF, Hiscott J.

Mol Cell Biol. 2009 Jun;29(12):3401-12. doi: 10.1128/MCB.00880-08. Epub 2009 Apr 20.

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