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Items: 1 to 20 of 101

1.

Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila.

Ling D, Song HJ, Garza D, Neufeld TP, Salvaterra PM.

PLoS One. 2009;4(1):e4201. doi: 10.1371/journal.pone.0004201. Epub 2009 Jan 15.

2.
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Accumulation of amyloid-like Aβ1-42 in AEL (autophagy-endosomal-lysosomal) vesicles: potential implications for plaque biogenesis.

Ling D, Magallanes M, Salvaterra PM.

ASN Neuro. 2014 Mar 12;6(2). pii: e00139. doi: 10.1042/AN20130044.

4.

LC3 overexpression reduces Aβ neurotoxicity through increasing α7nAchR expression and autophagic activity in neurons and mice.

Hung SY, Huang WP, Liou HC, Fu WM.

Neuropharmacology. 2015 Jun;93:243-51. doi: 10.1016/j.neuropharm.2015.02.003. Epub 2015 Feb 14.

PMID:
25686800
5.

Stimulation of autophagy prevents amyloid-β peptide-induced neuritic degeneration in PC12 cells.

Yang Y, Chen S, Zhang J, Li C, Sun Y, Zhang L, Zheng X.

J Alzheimers Dis. 2014;40(4):929-39. doi: 10.3233/JAD-132270.

PMID:
24531159
6.

Autophagy protects neuron from Abeta-induced cytotoxicity.

Hung SY, Huang WP, Liou HC, Fu WM.

Autophagy. 2009 May;5(4):502-10. Epub 2009 May 6.

PMID:
19270530
7.

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.

Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson D, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, Westaway D, Mathews PM, Levy E, Cuervo AM, Nixon RA.

Brain. 2011 Jan;134(Pt 1):258-77. doi: 10.1093/brain/awq341.

8.

A central role for autophagy in Alzheimer-type neurodegeneration.

Ling D, Salvaterra PM.

Autophagy. 2009 Jul;5(5):738-40. Epub 2009 Jul 2.

PMID:
19395865
9.

Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway.

Silva DF, Esteves AR, Arduino DM, Oliveira CR, Cardoso SM.

J Alzheimers Dis. 2011;26(3):565-81. doi: 10.3233/JAD-2011-110423.

PMID:
21694451
10.

The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo.

Knowles JK, Rajadas J, Nguyen TV, Yang T, LeMieux MC, Vander Griend L, Ishikawa C, Massa SM, Wyss-Coray T, Longo FM.

J Neurosci. 2009 Aug 26;29(34):10627-37. doi: 10.1523/JNEUROSCI.0620-09.2009.

11.

Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture.

Chen YS, Chen SD, Wu CL, Huang SS, Yang DI.

Exp Neurol. 2014 Mar;253:63-71. doi: 10.1016/j.expneurol.2013.12.009. Epub 2013 Dec 22.

PMID:
24368194
12.

Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death.

Soura V, Stewart-Parker M, Williams TL, Ratnayaka A, Atherton J, Gorringe K, Tuffin J, Darwent E, Rambaran R, Klein W, Lacor P, Staras K, Thorpe J, Serpell LC.

Biochem J. 2012 Jan 15;441(2):579-90. doi: 10.1042/BJ20110749.

PMID:
21955321
13.

TFEB Participates in the Aβ-Induced Pathogenesis of Alzheimer's Disease by Regulating the Autophagy-Lysosome Pathway.

Zhang YD, Zhao JJ.

DNA Cell Biol. 2015 Nov;34(11):661-8. doi: 10.1089/dna.2014.2738. Epub 2015 Sep 14.

PMID:
26368054
14.

Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.

Lonskaya I, Shekoyan AR, Hebron ML, Desforges N, Algarzae NK, Moussa CE.

J Alzheimers Dis. 2013;33(1):231-47. doi: 10.3233/JAD-2012-121141.

PMID:
22954671
15.

Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.

Wang C, Zhang X, Teng Z, Zhang T, Li Y.

Eur J Pharmacol. 2014 Oct 5;740:312-20. doi: 10.1016/j.ejphar.2014.06.051. Epub 2014 Jul 17.

PMID:
25041840
16.

Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models.

Shin JY, Park HJ, Kim HN, Oh SH, Bae JS, Ha HJ, Lee PH.

Autophagy. 2014 Jan;10(1):32-44. doi: 10.4161/auto.26508. Epub 2013 Jan 1.

17.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

18.

Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells.

Wang H, Ma J, Tan Y, Wang Z, Sheng C, Chen S, Ding J.

J Alzheimers Dis. 2010;21(2):597-610. doi: 10.3233/JAD-2010-091207.

PMID:
20571221
19.

Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy.

Joshi G, Gan KA, Johnson DA, Johnson JA.

Neurobiol Aging. 2015 Feb;36(2):664-79. doi: 10.1016/j.neurobiolaging.2014.09.004. Epub 2014 Sep 6.

20.

Decreased insulin-receptor signaling promotes the autophagic degradation of beta-amyloid peptide in C. elegans.

Florez-McClure ML, Hohsfield LA, Fonte G, Bealor MT, Link CD.

Autophagy. 2007 Nov-Dec;3(6):569-80. Epub 2007 Jul 20. Erratum in: Autophagy. 2009 Jan 1;5(1):132-3.

PMID:
17675890

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