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Items: 1 to 20 of 226

1.

Conformational changes in alpha 7 acetylcholine receptors underlying allosteric modulation by divalent cations.

McLaughlin JT, Barron SC, See JA, Rosenberg RL.

BMC Pharmacol. 2009 Jan 13;9:1. doi: 10.1186/1471-2210-9-1.

2.

Role of the outer beta-sheet in divalent cation modulation of alpha7 nicotinic receptors.

McLaughlin JT, Fu J, Sproul AD, Rosenberg RL.

Mol Pharmacol. 2006 Jul;70(1):16-22. Epub 2006 Mar 13.

3.

Glutamate 172, essential for modulation of L247T alpha7 ACh receptors by Ca2+, lines the extracellular vestibule.

Eddins D, Sproul AD, Lyford LK, McLaughlin JT, Rosenberg RL.

Am J Physiol Cell Physiol. 2002 Nov;283(5):C1454-60.

PMID:
12372806
4.

Potentiation of acetylcholine receptors by divalent cations.

Lindstrom J.

Mol Pharmacol. 2006 Jul;70(1):5-7. Epub 2006 Apr 26.

6.

Permeant but not impermeant divalent cations enhance activation of nondesensitizing alpha(7) nicotinic receptors.

Eddins D, Lyford LK, Lee JW, Desai SA, Rosenberg RL.

Am J Physiol Cell Physiol. 2002 Apr;282(4):C796-804.

PMID:
11880268
7.

Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors.

Lyford LK, Sproul AD, Eddins D, McLaughlin JT, Rosenberg RL.

Mol Pharmacol. 2003 Sep;64(3):650-8.

8.

The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations.

Weisstaub N, Vetter DE, Elgoyhen AB, Katz E.

Hear Res. 2002 May;167(1-2):122-35.

PMID:
12117536
9.
10.

Intra-subunit flexibility underlies activation and allosteric modulation of neuronal nicotinic acetylcholine receptors.

Chrisman PA, Podair JI, Jobe EM, Levandoski MM.

Neuropharmacology. 2014 Apr;79:420-31. doi: 10.1016/j.neuropharm.2013.12.017. Epub 2013 Dec 25.

12.

On the benzodiazepine binding pocket in GABAA receptors.

Berezhnoy D, Nyfeler Y, Gonthier A, Schwob H, Goeldner M, Sigel E.

J Biol Chem. 2004 Jan 30;279(5):3160-8. Epub 2003 Nov 11.

13.

Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.

Olsen JA, Kastrup JS, Peters D, Gajhede M, Balle T, Ahring PK.

J Biol Chem. 2013 Dec 13;288(50):35997-6006. doi: 10.1074/jbc.M113.498618. Epub 2013 Oct 29.

14.

Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization.

Collins T, Young GT, Millar NS.

Neuropharmacology. 2011 Dec;61(8):1306-13. doi: 10.1016/j.neuropharm.2011.07.035. Epub 2011 Jul 30.

15.

Allosteric modulation of neuronal nicotinic acetylcholine receptors.

Buisson B, Bertrand D.

J Physiol Paris. 1998 Apr;92(2):89-100. Review.

PMID:
9782450
16.

Acetylcholine receptor gating: movement in the alpha-subunit extracellular domain.

Purohit P, Auerbach A.

J Gen Physiol. 2007 Dec;130(6):569-79.

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20.

Key roles of hydrophobic rings of TM2 in gating of the alpha9alpha10 nicotinic cholinergic receptor.

Plazas PV, De Rosa MJ, Gomez-Casati ME, Verbitsky M, Weisstaub N, Katz E, Bouzat C, Elgoyhen AB.

Br J Pharmacol. 2005 Aug;145(7):963-74.

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