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Items: 1 to 20 of 93

1.

Network-level molecular evolutionary analysis of the insulin/TOR signal transduction pathway across 12 Drosophila genomes.

Alvarez-Ponce D, Aguadé M, Rozas J.

Genome Res. 2009 Feb;19(2):234-42. doi: 10.1101/gr.084038.108. Epub 2009 Jan 13.

2.

Comparative genomics of the vertebrate insulin/TOR signal transduction pathway: a network-level analysis of selective pressures.

Alvarez-Ponce D, Aguadé M, Rozas J.

Genome Biol Evol. 2011;3:87-101. doi: 10.1093/gbe/evq084. Epub 2010 Dec 13.

3.

Molecular population genetics of the insulin/TOR signal transduction pathway: a network-level analysis in Drosophila melanogaster.

Alvarez-Ponce D, Guirao-Rico S, Orengo DJ, Segarra C, Rozas J, Aguadé M.

Mol Biol Evol. 2012 Jan;29(1):123-32. doi: 10.1093/molbev/msr160. Epub 2011 Jun 16.

PMID:
21680868
4.
5.

Expression level drives the pattern of selective constraints along the insulin/Tor signal transduction pathway in Caenorhabditis.

Jovelin R, Phillips PC.

Genome Biol Evol. 2011;3:715-22. doi: 10.1093/gbe/evr071. Epub 2011 Aug 17.

6.

The evolution and origin of animal Toll-like receptor signaling pathway revealed by network-level molecular evolutionary analyses.

Song X, Jin P, Qin S, Chen L, Ma F.

PLoS One. 2012;7(12):e51657. doi: 10.1371/journal.pone.0051657. Epub 2012 Dec 7.

7.

Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations.

Luisi P, Alvarez-Ponce D, Dall'Olio GM, Sikora M, Bertranpetit J, Laayouni H.

Mol Biol Evol. 2012 May;29(5):1379-92. doi: 10.1093/molbev/msr298. Epub 2011 Dec 1.

PMID:
22135191
8.

Rapid molecular evolution across amniotes of the IIS/TOR network.

McGaugh SE, Bronikowski AM, Kuo CH, Reding DM, Addis EA, Flagel LE, Janzen FJ, Schwartz TS.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):7055-60. doi: 10.1073/pnas.1419659112. Epub 2015 May 19.

9.

Interspecific divergence of transcription networks along lines of genetic variance in Drosophila: dimensionality, evolvability, and constraint.

Innocenti P, Chenoweth SF.

Mol Biol Evol. 2013 Jun;30(6):1358-67. doi: 10.1093/molbev/mst047. Epub 2013 Mar 21.

PMID:
23519314
10.

Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster.

Nuzhdin SV, Brisson JA, Pickering A, Wayne ML, Harshman LG, McIntyre LM.

BMC Genomics. 2009 Mar 24;10:124. doi: 10.1186/1471-2164-10-124.

11.

Evolutionary rate patterns of genes involved in the Drosophila Toll and Imd signaling pathway.

Han M, Qin S, Song X, Li Y, Jin P, Chen L, Ma F.

BMC Evol Biol. 2013 Nov 8;13:245. doi: 10.1186/1471-2148-13-245.

12.

Evolution of the TOR pathway.

van Dam TJ, Zwartkruis FJ, Bos JL, Snel B.

J Mol Evol. 2011 Oct;73(3-4):209-20. doi: 10.1007/s00239-011-9469-9. Epub 2011 Nov 5.

13.

Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales.

Guirao-Rico S, Aguadé M.

Mol Biol Evol. 2009 Aug;26(8):1723-32. doi: 10.1093/molbev/msp088. Epub 2009 Apr 27.

PMID:
19398492
14.

Molecular evolution of the ligands of the insulin-signaling pathway: dilp genes in the genus Drosophila.

Guirao-Rico S, Aguadé M.

Mol Biol Evol. 2011 May;28(5):1557-60. doi: 10.1093/molbev/msq353. Epub 2010 Dec 31.

PMID:
21196470
15.

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo.

Parisi F, Riccardo S, Daniel M, Saqcena M, Kundu N, Pession A, Grifoni D, Stocker H, Tabak E, Bellosta P.

BMC Biol. 2011 Sep 27;9:65. doi: 10.1186/1741-7007-9-65.

16.

Evolutionary patterns of Toll-like receptor signaling pathway genes in the Suidae.

Darfour-Oduro KA, Megens HJ, Roca AL, Groenen MA, Schook LB.

BMC Evol Biol. 2016 Feb 9;16:33. doi: 10.1186/s12862-016-0602-7.

17.

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.

Glatter T, Schittenhelm RB, Rinner O, Roguska K, Wepf A, Jünger MA, Köhler K, Jevtov I, Choi H, Schmidt A, Nesvizhskii AI, Stocker H, Hafen E, Aebersold R, Gstaiger M.

Mol Syst Biol. 2011 Nov 8;7:547. doi: 10.1038/msb.2011.79.

18.

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.

Teleman AA, Hietakangas V, Sayadian AC, Cohen SM.

Cell Metab. 2008 Jan;7(1):21-32. doi: 10.1016/j.cmet.2007.11.010.

19.

DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway.

Killip LE, Grewal SS.

Dev Biol. 2012 Nov 15;371(2):191-202. doi: 10.1016/j.ydbio.2012.08.020. Epub 2012 Aug 31.

20.

Molecular evolution constraints in the floral organ specification gene regulatory network module across 18 angiosperm genomes.

Davila-Velderrain J, Servin-Marquez A, Alvarez-Buylla ER.

Mol Biol Evol. 2014 Mar;31(3):560-73. doi: 10.1093/molbev/mst223. Epub 2013 Nov 21.

PMID:
24273325

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