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Items: 1 to 20 of 132

1.

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.

Yoh SM, Lucas JS, Jones KA.

Genes Dev. 2008 Dec 15;22(24):3422-34. doi: 10.1101/gad.1720008.

2.

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.

Yoh SM, Cho H, Pickle L, Evans RM, Jones KA.

Genes Dev. 2007 Jan 15;21(2):160-74.

3.

The multi-tasking P-TEFb complex.

Brès V, Yoh SM, Jones KA.

Curr Opin Cell Biol. 2008 Jun;20(3):334-40. doi: 10.1016/j.ceb.2008.04.008. Epub 2008 May 29. Review.

4.

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.

Edmunds JW, Mahadevan LC, Clayton AL.

EMBO J. 2008 Jan 23;27(2):406-20. Epub 2007 Dec 20.

5.

Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36.

de Almeida SF, Grosso AR, Koch F, Fenouil R, Carvalho S, Andrade J, Levezinho H, Gut M, Eick D, Gut I, Andrau JC, Ferrier P, Carmo-Fonseca M.

Nat Struct Mol Biol. 2011 Jul 26;18(9):977-83. doi: 10.1038/nsmb.2123.

PMID:
21792193
6.

Roles for Ctk1 and Spt6 in regulating the different methylation states of histone H3 lysine 36.

Youdell ML, Kizer KO, Kisseleva-Romanova E, Fuchs SM, Duro E, Strahl BD, Mellor J.

Mol Cell Biol. 2008 Aug;28(16):4915-26. doi: 10.1128/MCB.00001-08. Epub 2008 Jun 9.

7.

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription.

Carvalho S, Raposo AC, Martins FB, Grosso AR, Sridhara SC, Rino J, Carmo-Fonseca M, de Almeida SF.

Nucleic Acids Res. 2013 Mar 1;41(5):2881-93. doi: 10.1093/nar/gks1472. Epub 2013 Jan 15.

8.

The role of cotranscriptional histone methylations.

Buratowski S, Kim T.

Cold Spring Harb Symp Quant Biol. 2010;75:95-102. doi: 10.1101/sqb.2010.75.036. Epub 2011 Mar 29.

9.

Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.

Hu M, Sun XJ, Zhang YL, Kuang Y, Hu CQ, Wu WL, Shen SH, Du TT, Li H, He F, Xiao HS, Wang ZG, Liu TX, Lu H, Huang QH, Chen SJ, Chen Z.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2956-61. doi: 10.1073/pnas.0915033107. Epub 2010 Jan 28.

11.

Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment.

Eissenberg JC, Shilatifard A, Dorokhov N, Michener DE.

Mol Genet Genomics. 2007 Feb;277(2):101-14. Epub 2006 Sep 26.

PMID:
17001490
12.

RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36.

Fuchs SM, Kizer KO, Braberg H, Krogan NJ, Strahl BD.

J Biol Chem. 2012 Jan 27;287(5):3249-56. doi: 10.1074/jbc.M111.273953. Epub 2011 Dec 7.

13.

Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation.

Hunter GO, Fox MJ, Smith-Kinnaman WR, Gogol M, Fleharty B, Mosley AL.

Mol Cell Biol. 2016 Aug 12;36(17):2236-45. doi: 10.1128/MCB.00870-15. Print 2016 Sep 1.

14.

SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.

Pfister SX, Ahrabi S, Zalmas LP, Sarkar S, Aymard F, Bachrati CZ, Helleday T, Legube G, La Thangue NB, Porter AC, Humphrey TC.

Cell Rep. 2014 Jun 26;7(6):2006-18. doi: 10.1016/j.celrep.2014.05.026. Epub 2014 Jun 12.

15.

Role of histone modifications in marking and activating genes through mitosis.

Valls E, Sánchez-Molina S, Martínez-Balbás MA.

J Biol Chem. 2005 Dec 30;280(52):42592-600. Epub 2005 Sep 30.

16.

SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing.

Zhu K, Lei PJ, Ju LG, Wang X, Huang K, Yang B, Shao C, Zhu Y, Wei G, Fu XD, Li L, Wu M.

Nucleic Acids Res. 2017 Jan 9;45(1):92-105. doi: 10.1093/nar/gkw814. Epub 2016 Sep 9.

17.

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.

Hacker KE, Fahey CC, Shinsky SA, Chiang YJ, DiFiore JV, Jha DK, Vo AH, Shavit JA, Davis IJ, Strahl BD, Rathmell WK.

J Biol Chem. 2016 Sep 30;291(40):21283-21295. Epub 2016 Aug 15.

PMID:
27528607
18.

Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.

Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A.

J Virol. 2004 Dec;78(24):13522-33.

19.

A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.

Kizer KO, Phatnani HP, Shibata Y, Hall H, Greenleaf AL, Strahl BD.

Mol Cell Biol. 2005 Apr;25(8):3305-16.

20.

Histone H3 lysine 4 trimethylation regulates cotranscriptional H2A variant exchange by Tip60 complexes to maximize gene expression.

Kusch T, Mei A, Nguyen C.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4850-5. doi: 10.1073/pnas.1320337111. Epub 2014 Mar 17.

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