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US intergroup anal carcinoma trial: tumor diameter predicts for colostomy.

Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG.

J Clin Oncol. 2009 Mar 1;27(7):1116-21. doi: 10.1200/JCO.2008.19.6857. Epub 2009 Jan 12.


Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin.

Gunderson LL, Winter KA, Ajani JA, Pedersen JE, Moughan J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG.

J Clin Oncol. 2012 Dec 10;30(35):4344-51. doi: 10.1200/JCO.2012.43.8085. Epub 2012 Nov 13.


Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.

Ajani JA, Winter KA, Gunderson LL, Pedersen J, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett C.

JAMA. 2008 Apr 23;299(16):1914-21. doi: 10.1001/jama.299.16.1914.


Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial.

Gunderson LL, Moughan J, Ajani JA, Pedersen JE, Winter KA, Benson AB 3rd, Thomas CR Jr, Mayer RJ, Haddock MG, Rich TA, Willett CG.

Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):638-45. doi: 10.1016/j.ijrobp.2013.07.035. Epub 2013 Sep 10.


Tumor site predicts outcome after radiochemotherapy in squamous-cell carcinoma of the anal region: long-term results of 101 patients.

Grabenbauer GG, Kessler H, Matzel KE, Sauer R, Hohenberger W, Schneider IH.

Dis Colon Rectum. 2005 Sep;48(9):1742-51.


Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.

Doyen J, Benezery K, Follana P, Ortholan C, Gérard JP, Hannoun-Levi JM, Gal J, Francois E.

Dis Colon Rectum. 2013 Oct;56(10):1125-33. doi: 10.1097/DCR.0b013e3182a226bd.


Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811.

Doll CM, Moughan J, Klimowicz A, Ho CK, Kornaga EN, Lees-Miller SP, Ajani JA, Crane CH, Kachnic LA, Okawara GS, Berk LB, Roof KS, Becker MJ, Grisell DL, Ellis RJ, Sperduto PW, Marsa GW, Guha C, Magliocco AM.

Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):554-562. doi: 10.1016/j.ijrobp.2016.11.021. Epub 2016 Nov 23.


[Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients].

Deniaud-Alexandre E, Touboul E, Tiret E, Sezeur A, Houry S, Gallot D, Parc R, Huang R, Qu SH, Pène F, Schlienger M.

Cancer Radiother. 2003 Aug;7(4):237-53. French.


Cisplatin-based combined modality therapy for anal carcinoma: a wider therapeutic index.

Hung A, Crane C, Delclos M, Ballo M, Ajani J, Lin E, Feig B, Skibber J, Janjan N.

Cancer. 2003 Mar 1;97(5):1195-202.


[Epidermoid carcinomas of anal canal treated with radiation therapy and concomitant chemotherapy (5-fluorouracil and cisplatin)].

Deniaud-Alexandre E, Touboul E, Tiret E, Sezeur A, Hannoun L, Houry S, Huguet F, Pène F, Parc R, Schlienger M.

Cancer Radiother. 2006 Dec;10(8):572-82. Epub 2006 Nov 15. French.


Mitomycin-C- or cisplatin-based chemoradiotherapy for anal canal carcinoma: long-term results.

Olivatto LO, Cabral V, Rosa A, Bezerra M, Santarem E, Fassizoli A, Castro L, Simões JH, Small IA, Ferreira CG.

Int J Radiat Oncol Biol Phys. 2011 Feb 1;79(2):490-5. doi: 10.1016/j.ijrobp.2009.11.057. Epub 2010 May 14.


Tumour- and treatment-related colostomy rates following mitomycin C or cisplatin chemoradiation with or without maintenance chemotherapy in squamous cell carcinoma of the anus in the ACT II trial.

Glynne-Jones R, Kadalayil L, Meadows HM, Cunningham D, Samuel L, Geh JI, Lowdell C, James R, Beare S, Begum R, Ledermann JA, Sebag-Montefiore D; ACT II Study Group.

Ann Oncol. 2014 Aug;25(8):1616-22. doi: 10.1093/annonc/mdu188. Epub 2014 May 14.


Review of anal cancer patients at the Ottawa hospital.

Abunassar M, Reinders J, Jonker DJ, Asmis T.

Eur J Surg Oncol. 2015 May;41(5):653-8. doi: 10.1016/j.ejso.2015.02.004. Epub 2015 Mar 4.


Outcomes of chemoradiotherapy with 5-Fluorouracil and mitomycin C for anal cancer in immunocompetent versus immunodeficient patients.

Seo Y, Kinsella MT, Reynolds HL, Chipman G, Remick SC, Kinsella TJ.

Int J Radiat Oncol Biol Phys. 2009 Sep 1;75(1):143-9. doi: 10.1016/j.ijrobp.2008.10.046. Epub 2009 Feb 7.


Epidermal growth factor receptor expression as prognostic marker in patients with anal carcinoma treated with concurrent chemoradiation therapy.

Fraunholz I, Rödel F, Kohler D, Diallo-Georgiopoulou M, Distel L, Falk S, Rödel C.

Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):901-7. doi: 10.1016/j.ijrobp.2013.03.039. Epub 2013 Jun 5.


Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.

Ben-Josef E, Moughan J, Ajani JA, Flam M, Gunderson L, Pollock J, Myerson R, Anne R, Rosenthal SA, Willett C.

J Clin Oncol. 2010 Dec 1;28(34):5061-6. doi: 10.1200/JCO.2010.29.1351. Epub 2010 Oct 18.


Chemoradiotherapy for squamous cell carcinoma of the anal canal: Comparison of one versus two cycles mitomycin-C.

White EC, Goldman K, Aleshin A, Lien WW, Rao AR.

Radiother Oncol. 2015 Nov;117(2):240-5. doi: 10.1016/j.radonc.2015.08.015. Epub 2015 Sep 4.


Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal.

Wong CS, Tsao MS, Sharma V, Chapman WB, Pintilie M, Cummings BJ.

Int J Radiat Oncol Biol Phys. 1999 Sep 1;45(2):309-14.


Long-term results of weekly/daily cisplatin-based chemoradiation for locally advanced squamous cell carcinoma of the anal canal.

Eng C, Chang GJ, You YN, Das P, Xing Y, Delclos M, Wolff RA, Rodriguez-Bigas MA, Skibber J, Ohinata A, Gould S, Phillips J, Crane CH.

Cancer. 2013 Nov 1;119(21):3769-75. doi: 10.1002/cncr.28296. Epub 2013 Aug 20.

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