Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 80

1.

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.

Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L.

Nat Chem Biol. 2009 Feb;5(2):100-7. doi: 10.1038/nchembio.137.

2.

[Dual-role regulations of canonical Wnt/beta-catenin signaling pathway].

Liu Y, Zhang CG, Zhou CY.

Beijing Da Xue Xue Bao. 2010 Apr 18;42(2):238-42. Review. Chinese.

3.

Small-molecule synergist of the Wnt/beta-catenin signaling pathway.

Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8. Erratum in: Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12581. Jian, Xiaoying [added]; Randazzo, Paul A [added].

4.

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.

Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356.

PMID:
19759537
5.

Wnt/beta-catenin signaling: components, mechanisms, and diseases.

MacDonald BT, Tamai K, He X.

Dev Cell. 2009 Jul;17(1):9-26. doi: 10.1016/j.devcel.2009.06.016. Review.

6.

Regulation of Wnt/beta-catenin signaling by protein kinases.

Verheyen EM, Gottardi CJ.

Dev Dyn. 2010 Jan;239(1):34-44. doi: 10.1002/dvdy.22019. Review.

7.

Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway.

Liu C, He X.

J Mol Cell Biol. 2010 Apr;2(2):70-3. doi: 10.1093/jmcb/mjp040.

8.

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.

Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM 3rd, Lee E.

Nat Chem Biol. 2010 Nov;6(11):829-36. doi: 10.1038/nchembio.453.

9.

Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions.

Jiang Y, Luo W, Howe PH.

Oncogene. 2009 Aug 20;28(33):2999-3007. doi: 10.1038/onc.2009.157.

10.
11.

Wnt/beta-catenin signaling: new (and old) players and new insights.

Huang H, He X.

Curr Opin Cell Biol. 2008 Apr;20(2):119-25. doi: 10.1016/j.ceb.2008.01.009. Review.

12.

Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway.

Hendriksen J, Jansen M, Brown CM, van der Velde H, van Ham M, Galjart N, Offerhaus GJ, Fagotto F, Fornerod M.

J Cell Sci. 2008 Jun 1;121(11):1793-802. doi: 10.1242/jcs.025536.

13.

Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1).

Tanneberger K, Pfister AS, Kriz V, Bryja V, Schambony A, Behrens J.

J Biol Chem. 2011 Jun 3;286(22):19204-14. doi: 10.1074/jbc.M111.224881.

14.

Wnt/beta-catenin pathway deregulation in childhood adrenocortical tumors.

Leal LF, Mermejo LM, Ramalho LZ, Martinelli CE Jr, Yunes JA, Seidinger AL, Mastellaro MJ, Cardinalli IA, Brandalise SR, Moreira AC, Tone LG, Scrideli CA, Castro M, Antonini SR.

J Clin Endocrinol Metab. 2011 Oct;96(10):3106-14. doi: 10.1210/jc.2011-0363.

PMID:
21849527
15.

Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.

Saraswati S, Alfaro MP, Thorne CA, Atkinson J, Lee E, Young PP.

PLoS One. 2010 Nov 29;5(11):e15521. doi: 10.1371/journal.pone.0015521.

16.

N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.

Haÿ E, Laplantine E, Geoffroy V, Frain M, Kohler T, Müller R, Marie PJ.

Mol Cell Biol. 2009 Feb;29(4):953-64. doi: 10.1128/MCB.00349-08.

17.

Long noncoding RNAs associated with liver regeneration 1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/β-catenin signaling.

Xu D, Yang F, Yuan JH, Zhang L, Bi HS, Zhou CC, Liu F, Wang F, Sun SH.

Hepatology. 2013 Aug;58(2):739-51. doi: 10.1002/hep.26361.

PMID:
23483581
18.

Early planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway.

Iglesias M, Almuedo-Castillo M, Aboobaker AA, Saló E.

Dev Biol. 2011 Oct 1;358(1):68-78. doi: 10.1016/j.ydbio.2011.07.013.

19.

Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine.

Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, Lum L.

J Biol Chem. 2012 Jun 29;287(27):23246-54. doi: 10.1074/jbc.M112.372029.

20.

The Wnt/β-catenin signaling pathway in liver biology and disease.

Behari J.

Expert Rev Gastroenterol Hepatol. 2010 Dec;4(6):745-56. doi: 10.1586/egh.10.74. Review.

Supplemental Content

Support Center