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Items: 1 to 20 of 105

1.

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S; International Multiple Sclerosis Genetics Consortium., De Jager PL, Wicker LS, Todd JA, Hafler DA.

PLoS Genet. 2009 Jan;5(1):e1000322. doi: 10.1371/journal.pgen.1000322.

2.

Multiple autoimmune-associated variants confer decreased IL-2R signaling in CD4+ CD25(hi) T cells of type 1 diabetic and multiple sclerosis patients.

Cerosaletti K, Schneider A, Schwedhelm K, Frank I, Tatum M, Wei S, Whalen E, Greenbaum C, Kita M, Buckner J, Long SA.

PLoS One. 2013 Dec 23;8(12):e83811. doi: 10.1371/journal.pone.0083811.

3.

Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.

Maier LM, Anderson DE, Severson CA, Baecher-Allan C, Healy B, Liu DV, Wittrup KD, De Jager PL, Hafler DA.

J Immunol. 2009 Feb 1;182(3):1541-7.

4.

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

Alcina A, Fedetz M, Ndagire D, Fernández O, Leyva L, Guerrero M, Abad-Grau MM, Arnal C, Delgado C, Lucas M, Izquierdo G, Matesanz F.

PLoS One. 2009;4(1):e4137. doi: 10.1371/journal.pone.0004137.

5.

Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus.

Perera D, Stankovich J, Butzkueven H, Taylor BV, Foote SJ, Kilpatrick TJ, Rubio JP.

J Neuroimmunol. 2009 Jun 25;211(1-2):105-9. doi: 10.1016/j.jneuroim.2009.03.010.

PMID:
19375175
6.

Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.

Espino-Paisán L, De La Calle H, Fernández-Arquero M, Figueredo MA, De La Concha EG, Urcelay E, Santiago JL.

Autoimmunity. 2011 Dec;44(8):624-30. doi: 10.3109/08916934.2011.592515.

PMID:
21875375
7.

A cis-acting regulatory variant in the IL2RA locus.

Qu HQ, Verlaan DJ, Ge B, Lu Y, Lam KC, Grabs R, Harmsen E, Hudson TJ, Hakonarson H, Pastinen T, Polychronakos C.

J Immunol. 2009 Oct 15;183(8):5158-62. doi: 10.4049/jimmunol.0901337.

8.

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

Carr EJ, Clatworthy MR, Lowe CE, Todd JA, Wong A, Vyse TJ, Kamesh L, Watts RA, Lyons PA, Smith KG.

BMC Med Genet. 2009 Mar 5;10:22. doi: 10.1186/1471-2350-10-22.

9.

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.

Dendrou CA, Plagnol V, Fung E, Yang JH, Downes K, Cooper JD, Nutland S, Coleman G, Himsworth M, Hardy M, Burren O, Healy B, Walker NM, Koch K, Ouwehand WH, Bradley JR, Wareham NJ, Todd JA, Wicker LS.

Nat Genet. 2009 Sep;41(9):1011-5. doi: 10.1038/ng.434.

10.

Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity.

Gutierrez-Achury J, Romanos J, Bakker SF, Kumar V, de Haas EC, Trynka G, Ricaño-Ponce I, Steck A; Type 1 Diabetes Genetics Consortium., Chen WM, Onengut-Gumuscu S, Simsek S; Diabeter., Rewers M, Mulder CJ, Liu E, Rich SS, Wijmenga C.

Diabetes Care. 2015 Oct;38 Suppl 2:S37-44. doi: 10.2337/dcs15-2007.

11.

Polymorphic variants of the IL2RA gene and susceptibility to type 1 diabetes in the Polish population.

Fichna M, Zurawek M, Fichna P, Januszkiewicz D, Nowak J.

Tissue Antigens. 2012 Mar;79(3):198-203. doi: 10.1111/j.1399-0039.2011.01828.x.

PMID:
22211793
12.

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA.

N Engl J Med. 2008 Dec 25;359(26):2767-77. doi: 10.1056/NEJMoa0807917.

13.

Risk alleles for multiple sclerosis in multiplex families.

D'Netto MJ, Ward H, Morrison KM, Ramagopalan SV, Dyment DA, DeLuca GC, Handunnetthi L, Sadovnick AD, Ebers GC.

Neurology. 2009 Jun 9;72(23):1984-8. doi: 10.1212/WNL.0b013e3181a92c25.

PMID:
19506219
14.

The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children.

Abdelrahman HM, Sherief LM, Abd Elrahman DM, Alghobashy A, Elsaadani HF, Mohamed RH.

Hum Immunol. 2016 Aug;77(8):682-6. doi: 10.1016/j.humimm.2016.06.006.

PMID:
27288719
15.

Association of common polymorphisms in the IL2RA gene with type 1 diabetes: evidence of 32,646 individuals from 10 independent studies.

Tang W, Cui D, Jiang L, Zhao L, Qian W, Long SA, Xu K.

J Cell Mol Med. 2015 Oct;19(10):2481-8. doi: 10.1111/jcmm.12642.

16.

Interleukin 2 receptor α gene polymorphism and risk of multiple sclerosis: a meta-analysis.

Wang LM, Zhang DM, Xu YM, Sun SL.

J Int Med Res. 2011;39(5):1625-35.

PMID:
22117963
17.

Risk alleles for multiple sclerosis identified by a genomewide study.

International Multiple Sclerosis Genetics Consortium., Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL.

N Engl J Med. 2007 Aug 30;357(9):851-62.

18.

IL2RA Allele Increases Risk of Neuromyelitis Optica in Southern Han Chinese.

Dai Y, Li J, Zhong X, Wang Y, Qiu W, Lu Z, Wu A, Bao J, Peng F, Hu X.

Can J Neurol Sci. 2013 Nov;40(6):832-5.

PMID:
24257225
19.

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, Bailey R, Bourget K, Plagnol V, Field S, Atkinson M, Clayton DG, Wicker LS, Todd JA.

Nat Genet. 2007 Sep;39(9):1074-82.

PMID:
17676041
20.

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

Wallace C, Cutler AJ, Pontikos N, Pekalski ML, Burren OS, Cooper JD, García AR, Ferreira RC, Guo H, Walker NM, Smyth DJ, Rich SS, Onengut-Gumuscu S, Sawcer SJ, Ban M, Richardson S, Todd JA, Wicker LS.

PLoS Genet. 2015 Jun 24;11(6):e1005272. doi: 10.1371/journal.pgen.1005272.

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