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Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition.

Yu Y, Maroney PA, Denker JA, Zhang XH, Dybkov O, Lührmann R, Jankowsky E, Chasin LA, Nilsen TW.

Cell. 2008 Dec 26;135(7):1224-36. doi: 10.1016/j.cell.2008.10.046.


Competing upstream 5' splice sites enhance the rate of proximal splicing.

Hicks MJ, Mueller WF, Shepard PJ, Hertel KJ.

Mol Cell Biol. 2010 Apr;30(8):1878-86. doi: 10.1128/MCB.01071-09. Epub 2010 Feb 1.


A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation.

Aznarez I, Barash Y, Shai O, He D, Zielenski J, Tsui LC, Parkinson J, Frey BJ, Rommens JM, Blencowe BJ.

Genome Res. 2008 Aug;18(8):1247-58. doi: 10.1101/gr.073155.107. Epub 2008 May 2.


Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x.

Cloutier P, Toutant J, Shkreta L, Goekjian S, Revil T, Chabot B.

J Biol Chem. 2008 Aug 1;283(31):21315-24. doi: 10.1074/jbc.M800353200. Epub 2008 Jun 5.


iCLIP predicts the dual splicing effects of TIA-RNA interactions.

Wang Z, Kayikci M, Briese M, Zarnack K, Luscombe NM, Rot G, Zupan B, Curk T, Ule J.

PLoS Biol. 2010 Oct 26;8(10):e1000530. doi: 10.1371/journal.pbio.1000530.


Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex.

Kotlajich MV, Crabb TL, Hertel KJ.

Mol Cell Biol. 2009 Feb;29(4):1072-82. doi: 10.1128/MCB.01071-08. Epub 2008 Dec 8.


General and specific functions of exonic splicing silencers in splicing control.

Wang Z, Xiao X, Van Nostrand E, Burge CB.

Mol Cell. 2006 Jul 7;23(1):61-70. Epub 2006 Jun 22.


Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides.

Villemaire J, Dion I, Elela SA, Chabot B.

J Biol Chem. 2003 Dec 12;278(50):50031-9. Epub 2003 Sep 30.


Conserved RNA cis-elements regulate alternative splicing of Lepidopteran doublesex.

Wang XY, Zheng ZZ, Song HS, Xu YZ.

Insect Biochem Mol Biol. 2014 Jan;44:1-11. doi: 10.1016/j.ibmb.2013.10.009. Epub 2013 Nov 12.


Alternative splicing regulation at tandem 3' splice sites.

Akerman M, Mandel-Gutfreund Y.

Nucleic Acids Res. 2006 Jan 3;34(1):23-31. Print 2006.


An intron element modulating 5' splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1.

Chabot B, Blanchette M, Lapierre I, La Branche H.

Mol Cell Biol. 1997 Apr;17(4):1776-86.


Extensive in silico analysis of NF1 splicing defects uncovers determinants for splicing outcome upon 5' splice-site disruption.

Wimmer K, Roca X, Beiglböck H, Callens T, Etzler J, Rao AR, Krainer AR, Fonatsch C, Messiaen L.

Hum Mutat. 2007 Jun;28(6):599-612.


Combinatorial splicing of exon pairs by two-site binding of U1 small nuclear ribonucleoprotein particle.

Grabowski PJ, Nasim FU, Kuo HC, Burch R.

Mol Cell Biol. 1991 Dec;11(12):5919-28.


The strength of the HIV-1 3' splice sites affects Rev function.

Kammler S, Otte M, Hauber I, Kjems J, Hauber J, Schaal H.

Retrovirology. 2006 Dec 4;3:89.


The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex.

Malca H, Shomron N, Ast G.

Mol Cell Biol. 2003 May;23(10):3442-55.

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