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Items: 1 to 20 of 267


Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response.

Thirone AC, Speight P, Zulys M, Rotstein OD, Szászi K, Pedersen SF, Kapus A.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C463-75. doi: 10.1152/ajpcell.00467.2008. Epub 2008 Dec 24.


Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway.

Lee S, Helfman DM.

J Biol Chem. 2004 Jan 16;279(3):1885-91. Epub 2003 Oct 14.


Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.

Yang N, Higuchi O, Ohashi K, Nagata K, Wada A, Kangawa K, Nishida E, Mizuno K.

Nature. 1998 Jun 25;393(6687):809-12.


Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

Rasmussen M, Alexander RT, Darborg BV, Møbjerg N, Hoffmann EK, Kapus A, Pedersen SF.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C197-212. Epub 2007 Oct 31.


Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors.

Hopkins AM, Pineda AA, Winfree LM, Brown GT, Laukoetter MG, Nusrat A.

Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G806-17. Epub 2006 Nov 30.


Osmotic stress-induced remodeling of the cortical cytoskeleton.

Di Ciano C, Nie Z, Szászi K, Lewis A, Uruno T, Zhan X, Rotstein OD, Mak A, Kapus A.

Am J Physiol Cell Physiol. 2002 Sep;283(3):C850-65.


LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta.

Vardouli L, Moustakas A, Stournaras C.

J Biol Chem. 2005 Mar 25;280(12):11448-57. Epub 2005 Jan 11.


Dynamic compression of chondrocytes induces a Rho kinase-dependent reorganization of the actin cytoskeleton.

Haudenschild DR, D'Lima DD, Lotz MK.

Biorheology. 2008;45(3-4):219-28.


B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization.

Klein RM, Spofford LS, Abel EV, Ortiz A, Aplin AE.

Mol Biol Cell. 2008 Feb;19(2):498-508. Epub 2007 Nov 28.


Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion.

Ding Y, Milosavljevic T, Alahari SK.

Mol Cell Biol. 2008 Jun;28(11):3742-56. doi: 10.1128/MCB.01832-07. Epub 2008 Mar 10.


Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S.

Science. 1999 Aug 6;285(5429):895-8.


Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.

Escuin S, Vernay B, Savery D, Gurniak CB, Witke W, Greene ND, Copp AJ.

J Cell Sci. 2015 Jul 15;128(14):2468-81. doi: 10.1242/jcs.164574. Epub 2015 Jun 3.


Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway.

Zhao XH, Laschinger C, Arora P, Szászi K, Kapus A, McCulloch CA.

J Cell Sci. 2007 May 15;120(Pt 10):1801-9. Epub 2007 Apr 24.


Osmotic stress activates Rac and Cdc42 in neutrophils: role in hypertonicity-induced actin polymerization.

Lewis A, Di Ciano C, Rotstein OD, Kapus A.

Am J Physiol Cell Physiol. 2002 Feb;282(2):C271-9.


Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2.

Sumi T, Matsumoto K, Takai Y, Nakamura T.

J Cell Biol. 1999 Dec 27;147(7):1519-32.


Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.

Pandey D, Goyal P, Bamburg JR, Siess W.

Blood. 2006 Jan 15;107(2):575-83. Epub 2005 Oct 11.

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