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Items: 1 to 20 of 98

1.

The human complement fragment receptor, C5L2, is a recycling decoy receptor.

Scola AM, Johswich KO, Morgan BP, Klos A, Monk PN.

Mol Immunol. 2009 Mar;46(6):1149-62. doi: 10.1016/j.molimm.2008.11.001. Epub 2008 Dec 18.

2.

C5a-stimulated recruitment of beta-arrestin2 to the nonsignaling 7-transmembrane decoy receptor C5L2.

Van Lith LH, Oosterom J, Van Elsas A, Zaman GJ.

J Biomol Screen. 2009 Oct;14(9):1067-75. doi: 10.1177/1087057109341407. Epub 2009 Jul 29.

PMID:
19641221
3.

C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation.

Cui W, Simaan M, Laporte S, Lodge R, Cianflone K.

Mol Immunol. 2009 Sep;46(15):3086-98. doi: 10.1016/j.molimm.2009.06.007. Epub 2009 Jul 16.

PMID:
19615750
4.

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

Bamberg CE, Mackay CR, Lee H, Zahra D, Jackson J, Lim YS, Whitfeld PL, Craig S, Corsini E, Lu B, Gerard C, Gerard NP.

J Biol Chem. 2010 Mar 5;285(10):7633-44. doi: 10.1074/jbc.M109.092106. Epub 2009 Dec 31.

5.

C5L2 is required for C5a-triggered receptor internalization and ERK signaling.

Hsu WC, Yang FC, Lin CH, Hsieh SL, Chen NJ.

Cell Signal. 2014 Jul;26(7):1409-19. doi: 10.1016/j.cellsig.2014.02.021. Epub 2014 Mar 12.

PMID:
24631530
6.

C5L2: a controversial receptor of complement anaphylatoxin, C5a.

Li R, Coulthard LG, Wu MC, Taylor SM, Woodruff TM.

FASEB J. 2013 Mar;27(3):855-64. doi: 10.1096/fj.12-220509. Epub 2012 Dec 13. Review.

PMID:
23239822
7.

Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis.

Wang R, Lu B, Gerard C, Gerard NP.

J Immunol. 2013 Oct 15;191(8):4001-9. doi: 10.4049/jimmunol.1301626. Epub 2013 Sep 16.

8.

The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding.

Scola AM, Higginbottom A, Partridge LJ, Reid RC, Woodruff T, Taylor SM, Fairlie DP, Monk PN.

J Biol Chem. 2007 Feb 9;282(6):3664-71. Epub 2006 Dec 11.

9.

C5L2, a nonsignaling C5A binding protein.

Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C.

Biochemistry. 2003 Aug 12;42(31):9406-15.

PMID:
12899627
11.

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.

Croker DE, Halai R, Fairlie DP, Cooper MA.

Immunol Cell Biol. 2013 Nov-Dec;91(10):625-33. doi: 10.1038/icb.2013.48. Epub 2013 Sep 24.

PMID:
24060963
12.
13.

C5L2 and C5aR interaction in adipocytes and macrophages: insights into adipoimmunology.

Poursharifi P, Lapointe M, Pétrin D, Devost D, Gauvreau D, Hébert TE, Cianflone K.

Cell Signal. 2013 Apr;25(4):910-8. doi: 10.1016/j.cellsig.2012.12.010. Epub 2012 Dec 23.

PMID:
23268185
14.

G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers.

Hüttenrauch F, Pollok-Kopp B, Oppermann M.

J Biol Chem. 2005 Nov 11;280(45):37503-15. Epub 2005 Sep 6.

15.

C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.

Croker DE, Halai R, Kaeslin G, Wende E, Fehlhaber B, Klos A, Monk PN, Cooper MA.

Immunol Cell Biol. 2014 Aug;92(7):631-9. doi: 10.1038/icb.2014.32. Epub 2014 Apr 29.

PMID:
24777312
17.

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation.

Bosmann M, Haggadone MD, Zetoune FS, Sarma JV, Ward PA.

Eur J Immunol. 2013 Jul;43(7):1907-13. doi: 10.1002/eji.201243075. Epub 2013 May 13.

18.

TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2.

Raby AC, Holst B, Davies J, Colmont C, Laumonnier Y, Coles B, Shah S, Hall J, Topley N, Köhl J, Morgan BP, Labéta MO.

Eur J Immunol. 2011 Sep;41(9):2741-52. doi: 10.1002/eji.201041350. Epub 2011 Aug 4.

19.

Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines.

Johswich K, Martin M, Thalmann J, Rheinheimer C, Monk PN, Klos A.

J Biol Chem. 2006 Dec 22;281(51):39088-95. Epub 2006 Oct 26.

20.

Functions of C5a receptors.

Ward PA.

J Mol Med (Berl). 2009 Apr;87(4):375-8. doi: 10.1007/s00109-009-0442-7. Epub 2009 Feb 3. Review.

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