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Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc.

Graves JA, Metukuri M, Scott D, Rothermund K, Prochownik EV.

J Biol Chem. 2009 Mar 6;284(10):6520-9. doi: 10.1074/jbc.M807564200. Epub 2008 Dec 19.


Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1.

Egler RA, Fernandes E, Rothermund K, Sereika S, de Souza-Pinto N, Jaruga P, Dizdaroglu M, Prochownik EV.

Oncogene. 2005 Dec 1;24(54):8038-50.


[Xenopus laevis peroxiredoxins: Gene expression during development and characterization of the enzymes].

Sharapov MG, Novoselov VI, Ravin VK.

Mol Biol (Mosk). 2016 Mar-Apr;50(2):336-46. doi: 10.7868/S002689841602021X. Russian.


Silencing Prx1 and/or Prx5 sensitizes human esophageal cancer cells to ionizing radiation and increases apoptosis via intracellular ROS accumulation.

Gao MC, Jia XD, Wu QF, Cheng Y, Chen FR, Zhang J.

Acta Pharmacol Sin. 2011 Apr;32(4):528-36. doi: 10.1038/aps.2010.235.


Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.

Kim YJ, Ahn JY, Liang P, Ip C, Zhang Y, Park YM.

Cancer Res. 2007 Jan 15;67(2):546-54.


MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species.

Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW.

Cancer Res. 2006 Jul 1;66(13):6598-605.


Peroxiredoxins, a novel target in cancer radiotherapy.

Zhang B, Wang Y, Su Y.

Cancer Lett. 2009 Dec 28;286(2):154-60. doi: 10.1016/j.canlet.2009.04.043. Epub 2009 Jun 4. Review.


Peroxiredoxin 1 (Prx1) is a dual-function enzyme by possessing Cys-independent catalase-like activity.

Sun CC, Dong WR, Shao T, Li JY, Zhao J, Nie L, Xiang LX, Zhu G, Shao JZ.

Biochem J. 2017 Apr 4;474(8):1373-1394. doi: 10.1042/BCJ20160851.


Distinct characteristics of two 2-Cys peroxiredoxins of Vibrio vulnificus suggesting differential roles in detoxifying oxidative stress.

Bang YJ, Oh MH, Choi SH.

J Biol Chem. 2012 Dec 14;287(51):42516-24. doi: 10.1074/jbc.M112.421214. Epub 2012 Oct 24.


Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc.

Gertz M, Fischer F, Leipelt M, Wolters D, Steegborn C.

Aging (Albany NY). 2009 Jan 30;1(2):254-65.


Fortilin potentiates the peroxidase activity of Peroxiredoxin-1 and protects against alcohol-induced liver damage in mice.

Chattopadhyay A, Pinkaew D, Doan HQ, Jacob RB, Verma SK, Friedman H, Peterson AC, Kuyumcu-Martinez MN, McDougal OM, Fujise K.

Sci Rep. 2016 Jan 4;6:18701. doi: 10.1038/srep18701.


Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production.

Yang Y, Cuevas S, Yang S, Villar VA, Escano C, Asico L, Yu P, Jiang X, Weinman EJ, Armando I, Jose PA.

Hypertension. 2014 Oct;64(4):825-32. doi: 10.1161/HYPERTENSIONAHA.114.03840. Epub 2014 Jul 14.


Downregulation of the c-MYC target gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.

Vivas-Mejía PE, Ozpolat B, Chen X, Lopez-Berestein G.

Int J Cancer. 2009 Jul 15;125(2):264-75. doi: 10.1002/ijc.24341.


Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.

Ducrest AL, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J.

Cancer Res. 2001 Oct 15;61(20):7594-602.


ATM controls c-Myc and DNA synthesis during postnatal thymocyte development through regulation of redox state.

Yan M, Zhu C, Liu N, Jiang Y, Scofield VL, Riggs PK, Qiang W, Lynn WS, Wong PK.

Free Radic Biol Med. 2006 Aug 15;41(4):640-8. Epub 2006 May 22.


RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3.

Huang M, Kamasani U, Prendergast GC.

Oncogene. 2006 Mar 2;25(9):1281-9.


Suppression of c-myc expression and c-Myc function in response to sustained DNA damage in MCF-7 breast tumor cells.

Magnet KJ, Orr MS, Cleveland JL, Rodriguez-Galindo C, Yang H, Yang C, Di YM, Jain PT, Gewirtz DA.

Biochem Pharmacol. 2001 Sep 1;62(5):593-602.


Altered subcellular localization of c-Myc protein identifies aggressive B-cell lymphomas harboring a c-MYC translocation.

Ruzinova MB, Caron T, Rodig SJ.

Am J Surg Pathol. 2010 Jun;34(6):882-91. doi: 10.1097/PAS.0b013e3181db83af.


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