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Items: 1 to 20 of 91

1.

The Toll-->NFkappaB signaling pathway mediates the neuropathological effects of the human Alzheimer's Abeta42 polypeptide in Drosophila.

Tan L, Schedl P, Song HJ, Garza D, Konsolaki M.

PLoS One. 2008;3(12):e3966. doi: 10.1371/journal.pone.0003966. Epub 2008 Dec 17.

2.

Homeotic Gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration.

Moran MT, Tare M, Kango-Singh M, Singh A.

PLoS One. 2013 Nov 25;8(11):e80829. doi: 10.1371/journal.pone.0080829. eCollection 2013.

3.

Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.

Lang M, Fan Q, Wang L, Zheng Y, Xiao G, Wang X, Wang W, Zhong Y, Zhou B.

Neurobiol Aging. 2013 Nov;34(11):2604-12. doi: 10.1016/j.neurobiolaging.2013.05.029. Epub 2013 Jul 2.

4.

The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease.

Lee S, Bang SM, Hong YK, Lee JH, Jeong H, Park SH, Liu QF, Lee IS, Cho KS.

Dis Model Mech. 2016 Mar;9(3):295-306. doi: 10.1242/dmm.018069. Epub 2015 Dec 10.

5.

The Drosophila Toll signaling pathway.

Valanne S, Wang JH, Rämet M.

J Immunol. 2011 Jan 15;186(2):649-56. doi: 10.4049/jimmunol.1002302. Review.

6.

Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer's Disease.

Cutler T, Sarkar A, Moran M, Steffensmeier A, Puli OR, Mancini G, Tare M, Gogia N, Singh A.

PLoS One. 2015 Sep 14;10(9):e0137691. doi: 10.1371/journal.pone.0137691. eCollection 2015.

7.

Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.

Iijima K, Gatt A, Iijima-Ando K.

Hum Mol Genet. 2010 Aug 1;19(15):2947-57. doi: 10.1093/hmg/ddq200. Epub 2010 May 12.

8.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

9.

Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila.

Wu C, Chen C, Dai J, Zhang F, Chen Y, Li W, Pastor-Pareja JC, Xue L.

Open Biol. 2015 Jul;5(7):140171. doi: 10.1098/rsob.140171.

10.

Vertebrate Rel proteins exhibit Dorsal-like activities in early Drosophila embryogenesis.

Prothmann C, Armstrong NJ, Roth S, Rupp RA.

Dev Dyn. 2006 Apr;235(4):949-57.

11.
12.

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease.

Iijima K, Liu HP, Chiang AS, Hearn SA, Konsolaki M, Zhong Y.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6623-8. Epub 2004 Apr 6.

13.
14.

Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.

Chen LY, Wang JC, Hyvert Y, Lin HP, Perrimon N, Imler JL, Hsu JC.

Curr Biol. 2006 Jun 20;16(12):1183-93.

15.

A nonhuman primate model of Alzheimer's disease generated by intracranial injection of amyloid-β42 and thiorphan.

Li W, Wu Y, Min F, Li Z, Huang J, Huang R.

Metab Brain Dis. 2010 Sep;25(3):277-84. doi: 10.1007/s11011-010-9207-9. Epub 2010 Sep 14.

PMID:
20838863
16.

Activation of JNK signaling mediates amyloid-ß-dependent cell death.

Tare M, Modi RM, Nainaparampil JJ, Puli OR, Bedi S, Fernandez-Funez P, Kango-Singh M, Singh A.

PLoS One. 2011;6(9):e24361. doi: 10.1371/journal.pone.0024361. Epub 2011 Sep 14.

17.

Toll and Toll-like proteins: an ancient family of receptors signaling infection.

Imler JL, Hoffmann JA.

Rev Immunogenet. 2000;2(3):294-304. Review.

PMID:
11256741
18.

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease.

Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T.

FASEB J. 2005 Feb;19(2):255-7. Epub 2004 Nov 17.

PMID:
15548589
19.
20.

Regulated nuclear import of Rel proteins in the Drosophila immune response.

Wu LP, Anderson KV.

Nature. 1998 Mar 5;392(6671):93-7.

PMID:
9510254

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