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Items: 1 to 20 of 125

1.

The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling.

Ikeda M, Longnecker R.

Virology. 2009 Mar 1;385(1):183-91. doi: 10.1016/j.virol.2008.11.018. Epub 2008 Dec 10.

2.

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.

Winberg G, Matskova L, Chen F, Plant P, Rotin D, Gish G, Ingham R, Ernberg I, Pawson T.

Mol Cell Biol. 2000 Nov;20(22):8526-35.

3.
4.

Epstein-Barr virus Latent Membrane Protein 2A (LMP2A)-mediated changes in Fas expression and Fas-dependent apoptosis: Role of Lyn/Syk activation.

Incrocci R, Hussain S, Stone A, Bieging K, Alt LA, Fay MJ, Swanson-Mungerson M.

Cell Immunol. 2015 Oct;297(2):108-19. doi: 10.1016/j.cellimm.2015.08.001. Epub 2015 Aug 4.

5.

The Epstein-Barr virus protein, latent membrane protein 2A, co-opts tyrosine kinases used by the T cell receptor.

Ingham RJ, Raaijmakers J, Lim CS, Mbamalu G, Gish G, Chen F, Matskova L, Ernberg I, Winberg G, Pawson T.

J Biol Chem. 2005 Oct 7;280(40):34133-42. Epub 2005 Aug 8.

6.
7.

Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling.

Ikeda A, Caldwell RG, Longnecker R, Ikeda M.

J Virol. 2003 May;77(9):5529-34.

8.
9.

Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module.

Engels N, Merchant M, Pappu R, Chan AC, Longnecker R, Wienands J.

J Exp Med. 2001 Aug 6;194(3):255-64.

10.

Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk- and Akt-dependent epithelial migration through αv-integrin membrane translocation.

Fotheringham JA, Coalson NE, Raab-Traub N.

J Virol. 2012 Oct;86(19):10308-20. doi: 10.1128/JVI.00853-12. Epub 2012 Jul 25.

12.

Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.

Hatton O, Lambert SL, Krams SM, Martinez OM.

PLoS One. 2012;7(8):e42610. doi: 10.1371/journal.pone.0042610. Epub 2012 Aug 3.

13.

The Shb signalling scaffold binds to and regulates constitutive signals from the Epstein-Barr virus LMP2A membrane protein.

Matskova LV, Helmstetter C, Ingham RJ, Gish G, Lindholm CK, Ernberg I, Pawson T, Winberg G.

Oncogene. 2007 Jul 26;26(34):4908-17. Epub 2007 Feb 19.

PMID:
17311000
14.
15.

Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9.

Lan YY, Hsiao JR, Chang KC, Chang JS, Chen CW, Lai HC, Wu SY, Yeh TH, Chang FH, Lin WH, Su IJ, Chang Y.

J Virol. 2012 Jun;86(12):6656-67. doi: 10.1128/JVI.00174-12. Epub 2012 Apr 18.

16.

Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction.

Miller CL, Lee JH, Kieff E, Burkhardt AL, Bolen JB, Longnecker R.

Infect Agents Dis. 1994 Apr-Jun;3(2-3):128-36. Review.

PMID:
7812651
17.

The LMP2A protein of Epstein-Barr virus regulates phosphorylation of ITSN1 and Shb adaptors by tyrosine kinases.

Dergai O, Dergai M, Skrypkina I, Matskova L, Tsyba L, Gudkova D, Rynditch A.

Cell Signal. 2013 Jan;25(1):33-40. doi: 10.1016/j.cellsig.2012.09.011. Epub 2012 Sep 10.

PMID:
22975684
18.

Epstein-Barr Virus Latent Membrane Protein 2A (LMP2A) enhances IL-10 production through the activation of Bruton's tyrosine kinase and STAT3.

Incrocci R, Barse L, Stone A, Vagvala S, Montesano M, Subramaniam V, Swanson-Mungerson M.

Virology. 2017 Jan;500:96-102. doi: 10.1016/j.virol.2016.10.015. Epub 2016 Oct 25.

19.

The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.

Katkere B, Rosa S, Drake JR.

J Biol Chem. 2012 May 11;287(20):16636-44. doi: 10.1074/jbc.M112.357640. Epub 2012 Mar 27.

20.

Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.

Swart R, Ruf IK, Sample J, Longnecker R.

J Virol. 2000 Nov;74(22):10838-45.

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