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Items: 1 to 20 of 142

1.

Activation of ATM depends on chromatin interactions occurring before induction of DNA damage.

Kim YC, Gerlitz G, Furusawa T, Catez F, Nussenzweig A, Oh KS, Kraemer KH, Shiloh Y, Bustin M.

Nat Cell Biol. 2009 Jan;11(1):92-6. doi: 10.1038/ncb1817. Epub 2008 Dec 14.

2.

Telomeres, histone code, and DNA damage response.

Misri S, Pandita S, Kumar R, Pandita TK.

Cytogenet Genome Res. 2008;122(3-4):297-307. doi: 10.1159/000167816. Epub 2009 Jan 30. Review.

3.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
4.

Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.

Rass E, Chandramouly G, Zha S, Alt FW, Xie A.

J Biol Chem. 2013 Mar 8;288(10):7086-95. doi: 10.1074/jbc.M112.445825. Epub 2013 Jan 26.

5.

Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.

Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.

Mol Cell Biol. 2005 Jan;25(2):661-70.

6.

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo.

Daniel JA, Pellegrini M, Lee JH, Paull TT, Feigenbaum L, Nussenzweig A.

J Cell Biol. 2008 Dec 1;183(5):777-83. doi: 10.1083/jcb.200805154.

7.

Replication independent DNA double-strand break retention may prevent genomic instability.

Kongruttanachok N, Phuangphairoj C, Thongnak A, Ponyeam W, Rattanatanyong P, Pornthanakasem W, Mutirangura A.

Mol Cancer. 2010 Mar 31;9:70. doi: 10.1186/1476-4598-9-70.

8.

Involvement of human MOF in ATM function.

Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK.

Mol Cell Biol. 2005 Jun;25(12):5292-305.

9.

Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radio-sensitisation in the absence of NF-κB activation.

Veuger SJ, Durkacz BW.

DNA Repair (Amst). 2011 Feb 7;10(2):235-44. doi: 10.1016/j.dnarep.2010.11.005. Epub 2010 Dec 8.

PMID:
21144805
10.

Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells.

Drissi R, Wu J, Hu Y, Bockhold C, Dome JS.

Cancer Prev Res (Phila). 2011 Dec;4(12):1973-81. doi: 10.1158/1940-6207.CAPR-11-0069. Epub 2011 Sep 19.

11.

Qualitative and quantitative analysis of phosphorylated ATM foci induced by low-dose ionizing radiation.

Suzuki K, Okada H, Yamauchi M, Oka Y, Kodama S, Watanabe M.

Radiat Res. 2006 May;165(5):499-504.

PMID:
16669703
12.

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.

Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Löbrich M, Jeggo PA.

Mol Cell. 2008 Jul 25;31(2):167-77. doi: 10.1016/j.molcel.2008.05.017.

13.

Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.

Taylor AM, Groom A, Byrd PJ.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1219-25. Review.

PMID:
15279810
14.

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG.

Cell Cycle. 2011 Jul 1;10(13):2218-32. Epub 2011 Jul 1.

PMID:
21623170
15.

Chfr and RNF8 synergistically regulate ATM activation.

Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X.

Nat Struct Mol Biol. 2011 Jun 26;18(7):761-8. doi: 10.1038/nsmb.2078.

16.

ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response.

Jang ER, Choi JD, Park MA, Jeong G, Cho H, Lee JS.

Exp Mol Med. 2010 Mar 31;42(3):195-204.

17.

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK.

Mol Cell Biol. 2010 Jul;30(14):3582-95. doi: 10.1128/MCB.01476-09. Epub 2010 May 17.

18.

ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage.

Bensimon A, Schmidt A, Ziv Y, Elkon R, Wang SY, Chen DJ, Aebersold R, Shiloh Y.

Sci Signal. 2010 Dec 7;3(151):rs3. doi: 10.1126/scisignal.2001034.

19.

Role of chromatin structure modulation by the histone deacetylase inhibitor trichostatin A on the radio-sensitivity of ataxia telangiectasia.

Meschini R, Morucci E, Berni A, Lopez-Martinez W, Palitti F.

Mutat Res. 2015 Jul;777:52-9. doi: 10.1016/j.mrfmmm.2015.04.009. Epub 2015 Apr 20.

PMID:
25942615
20.

MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.

Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y.

Mol Cell Biol. 2010 Nov;30(22):5335-47. doi: 10.1128/MCB.00350-10. Epub 2010 Sep 13.

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