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Items: 1 to 20 of 102

1.

Aurora-A kinase is essential for bipolar spindle formation and early development.

Cowley DO, Rivera-Pérez JA, Schliekelman M, He YJ, Oliver TG, Lu L, O'Quinn R, Salmon ED, Magnuson T, Van Dyke T.

Mol Cell Biol. 2009 Feb;29(4):1059-71. doi: 10.1128/MCB.01062-08. Epub 2008 Dec 15.

2.

Aurora A is essential for early embryonic development and tumor suppression.

Lu LY, Wood JL, Ye L, Minter-Dykhouse K, Saunders TL, Yu X, Chen J.

J Biol Chem. 2008 Nov 14;283(46):31785-90. doi: 10.1074/jbc.M805880200. Epub 2008 Sep 17.

3.
4.

Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality.

Sasai K, Parant JM, Brandt ME, Carter J, Adams HP, Stass SA, Killary AM, Katayama H, Sen S.

Oncogene. 2008 Jul 3;27(29):4122-7. doi: 10.1038/onc.2008.47. Epub 2008 Mar 17.

PMID:
18345035
5.

Depletion of Aurora-A in zebrafish causes growth retardation due to mitotic delay and p53-dependent cell death.

Jeon HY, Lee H.

FEBS J. 2013 Mar;280(6):1518-30. doi: 10.1111/febs.12153. Epub 2013 Feb 24.

6.

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

Fernández-Miranda G, Trakala M, Martín J, Escobar B, González A, Ghyselinck NB, Ortega S, Cañamero M, Pérez de Castro I, Malumbres M.

Development. 2011 Jul;138(13):2661-72. doi: 10.1242/dev.066381. Epub 2011 May 25.

7.

Phosphorylation of histone H3 serine 10 in early mouse embryos: active phosphorylation at late S phase and differential effects of ZM447439 on first two embryonic mitoses.

Teperek-Tkacz M, Meglicki M, Pasternak M, Kubiak JZ, Borsuk E.

Cell Cycle. 2010 Dec 1;9(23):4674-87. Epub 2010 Dec 1.

PMID:
21099354
8.

Astrin regulates Aurora-A localization.

Du J, Jablonski S, Yen TJ, Hannon GJ.

Biochem Biophys Res Commun. 2008 May 30;370(2):213-9. doi: 10.1016/j.bbrc.2008.03.072. Epub 2008 Mar 24.

9.

Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.

Park I, Lee HO, Choi E, Lee YK, Kwon MS, Min J, Park PG, Lee S, Kong YY, Gong G, Lee H.

J Cell Biol. 2013 Jul 22;202(2):295-309. doi: 10.1083/jcb.201210099.

10.

A kinase-independent role for Aurora A in the assembly of mitotic spindle microtubules in Caenorhabditis elegans embryos.

Toya M, Terasawa M, Nagata K, Iida Y, Sugimoto A.

Nat Cell Biol. 2011 Jun;13(6):708-14. doi: 10.1038/ncb2242. Epub 2011 May 15.

PMID:
21572421
11.

Conditional Aurora A deficiency differentially affects early mouse embryo patterning.

Yoon Y, Cowley DO, Gallant J, Jones SN, Van Dyke T, Rivera-Pérez JA.

Dev Biol. 2012 Nov 1;371(1):77-85. doi: 10.1016/j.ydbio.2012.08.010. Epub 2012 Aug 25. Erratum in: Dev Biol. 2012 Dec 1;372(1):156.

12.

Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest.

Coon TA, Glasser JR, Mallampalli RK, Chen BB.

Cell Cycle. 2012 Feb 15;11(4):721-9. doi: 10.4161/cc.11.4.19171. Epub 2012 Feb 15.

13.

Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression.

Liu X, Shi Y, Woods KW, Hessler P, Kroeger P, Wilsbacher J, Wang J, Wang JY, Li C, Li Q, Rosenberg SH, Giranda VL, Luo Y.

Neoplasia. 2008 Aug;10(8):828-37.

14.

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol.

Anand S, Penrhyn-Lowe S, Venkitaraman AR.

Cancer Cell. 2003 Jan;3(1):51-62.

15.

Requirement of aurora-A kinase in astral microtubule polymerization and spindle microtubule flux.

Wang LH, Yan M, Xu DZ, Cao JX, Zhu XF, Zeng YX, Liu Q.

Cell Cycle. 2008 Apr 15;7(8):1104-11. Epub 2008 Feb 11.

PMID:
18414060
16.

A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic process.

Ritchey L, Ottman R, Roumanos M, Chakrabarti R.

Cell Cycle. 2012 Jan 15;11(2):296-309. doi: 10.4161/cc.11.2.18734. Epub 2012 Jan 15.

17.

ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.

Venoux M, Basbous J, Berthenet C, Prigent C, Fernandez A, Lamb NJ, Rouquier S.

Hum Mol Genet. 2008 Jan 15;17(2):215-24. Epub 2007 Oct 9.

PMID:
17925329
18.

A MEK-independent role for CRAF in mitosis and tumor progression.

Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA.

Nat Med. 2011 Nov 13;17(12):1641-5. doi: 10.1038/nm.2464.

19.

The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.

Yabuta N, Mukai S, Okada N, Aylon Y, Nojima H.

Cell Cycle. 2011 Aug 15;10(16):2724-36. Epub 2011 Aug 15.

PMID:
21822051
20.

Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.

Du J, Hannon GJ.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8975-80. Epub 2004 Jun 3.

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