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Items: 1 to 20 of 367

1.

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.

Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK.

Diabetes. 2009 Mar;58(3):590-9. doi: 10.2337/db08-0913. Epub 2008 Dec 15.

2.

Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Panzhinskiy E, Ren J, Nair S.

PLoS One. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228. eCollection 2013.

3.

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress.

Agouni A, Mody N, Owen C, Czopek A, Zimmer D, Bentires-Alj M, Bence KK, Delibegović M.

Biochem J. 2011 Sep 1;438(2):369-78. doi: 10.1042/BJ20110373.

4.

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

Delibegovic M, Bence KK, Mody N, Hong EG, Ko HJ, Kim JK, Kahn BB, Neel BG.

Mol Cell Biol. 2007 Nov;27(21):7727-34. Epub 2007 Aug 27.

5.

Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice.

Lees EK, Krol E, Shearer K, Mody N, Gettys TW, Delibegovic M.

Metabolism. 2015 Feb;64(2):305-14. doi: 10.1016/j.metabol.2014.10.038. Epub 2014 Nov 5.

6.

Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice.

Owen C, Lees EK, Grant L, Zimmer DJ, Mody N, Bence KK, Delibegović M.

Diabetologia. 2013 Oct;56(10):2286-96. doi: 10.1007/s00125-013-2992-z. Epub 2013 Jul 6.

PMID:
23832083
7.

Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction.

Agouni A, Tual-Chalot S, Chalopin M, Duluc L, Mody N, Martinez MC, Andriantsitohaina R, Delibegović M.

Biochem Pharmacol. 2014 Dec 15;92(4):607-17. doi: 10.1016/j.bcp.2014.10.008. Epub 2014 Oct 30.

PMID:
25451690
8.

Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.

Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, Mcilroy GD, Göransson O, Welch A, Bence KK, Kahn BB, Neel BG, Mody N, Delibegović M.

PLoS One. 2012;7(2):e32700. doi: 10.1371/journal.pone.0032700. Epub 2012 Feb 28.

9.

Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia through an IL-10 STAT3-dependent mechanism.

Grant L, Shearer KD, Czopek A, Lees EK, Owen C, Agouni A, Workman J, Martin-Granados C, Forrester JV, Wilson HM, Mody N, Delibegovic M.

Diabetes. 2014 Feb;63(2):456-70. doi: 10.2337/db13-0885. Epub 2013 Nov 1.

10.

Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase.

Bettaieb A, Liu S, Xi Y, Nagata N, Matsuo K, Matsuo I, Chahed S, Bakke J, Keilhack H, Tiganis T, Haj FG.

J Biol Chem. 2011 Mar 18;286(11):9225-35. doi: 10.1074/jbc.M110.186148. Epub 2011 Jan 7.

11.

Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy.

Kandadi MR, Panzhinskiy E, Roe ND, Nair S, Hu D, Sun A.

Biochim Biophys Acta. 2015 Feb;1852(2):299-309. doi: 10.1016/j.bbadis.2014.07.004. Epub 2014 Jul 10.

12.

Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.

Bettaieb A, Matsuo K, Matsuo I, Wang S, Melhem R, Koromilas AE, Haj FG.

PLoS One. 2012;7(4):e34412. doi: 10.1371/journal.pone.0034412. Epub 2012 Apr 3.

13.

Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.

Latreille M, Laberge MK, Bourret G, Yamani L, Larose L.

Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E423-34. doi: 10.1152/ajpendo.00088.2010. Epub 2010 Jun 29.

14.

Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice.

Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG.

J Biol Chem. 2005 Apr 15;280(15):15038-46. Epub 2005 Feb 7.

15.

T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.

Fukushima A, Loh K, Galic S, Fam B, Shields B, Wiede F, Tremblay ML, Watt MJ, Andrikopoulos S, Tiganis T.

Diabetes. 2010 Aug;59(8):1906-14. doi: 10.2337/db09-1365. Epub 2010 May 18.

16.

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice.

Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, Saghatelian A, White FM.

Integr Biol (Camb). 2013 Jul 24;5(7):940-63. doi: 10.1039/c3ib40013a. Epub 2013 May 20.

17.

Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.

González-Rodríguez A, Mas Gutierrez JA, Sanz-González S, Ros M, Burks DJ, Valverde AM.

Diabetes. 2010 Mar;59(3):588-99. doi: 10.2337/db09-0796. Epub 2009 Dec 22.

18.

Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes.

Panzhinskiy E, Hua Y, Culver B, Ren J, Nair S.

Diabetologia. 2013 Mar;56(3):598-607. doi: 10.1007/s00125-012-2782-z. Epub 2012 Nov 24.

19.

Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.

Tsou RC, Zimmer DJ, De Jonghe BC, Bence KK.

Endocrinology. 2012 Sep;153(9):4227-37. doi: 10.1210/en.2012-1548. Epub 2012 Jul 16.

20.

Leptin increases hepatic insulin sensitivity and protein tyrosine phosphatase 1B expression.

Lam NT, Lewis JT, Cheung AT, Luk CT, Tse J, Wang J, Bryer-Ash M, Kolls JK, Kieffer TJ.

Mol Endocrinol. 2004 Jun;18(6):1333-45. Epub 2004 Feb 19.

PMID:
14976221

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