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Items: 1 to 20 of 82

1.

Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice.

Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH Jr, Nikolova-Karakashian M.

J Biol Chem. 2009 Mar 27;284(13):8359-68. doi: 10.1074/jbc.M807800200. Epub 2008 Dec 11.

2.

Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet.

Deevska GM, Sunkara M, Morris AJ, Nikolova-Karakashian MN.

Biosci Rep. 2012 Oct;32(5):479-90. doi: 10.1042/BSR20120036.

3.

Effect of high fat diet enriched with unsaturated and diet rich in saturated fatty acids on sphingolipid metabolism in rat skeletal muscle.

Blachnio-Zabielska A, Baranowski M, Zabielski P, Gorski J.

J Cell Physiol. 2010 Nov;225(3):786-91. doi: 10.1002/jcp.22283.

PMID:
20568228
4.

Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.

Shah C, Yang G, Lee I, Bielawski J, Hannun YA, Samad F.

J Biol Chem. 2008 May 16;283(20):13538-48. doi: 10.1074/jbc.M709950200. Epub 2008 Mar 22.

5.

PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet.

Baranowski M, Błachnio A, Zabielski P, Górski J.

J Physiol Pharmacol. 2007 Mar;58(1):57-72.

6.

Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression.

Devlin CM, Leventhal AR, Kuriakose G, Schuchman EH, Williams KJ, Tabas I.

Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1723-30. doi: 10.1161/ATVBAHA.108.173344. Epub 2008 Jul 31.

7.

Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats.

Babenko NA, Kharchenko VS.

Biochemistry (Mosc). 2015 Jan;80(1):104-12. doi: 10.1134/S0006297915010125.

PMID:
25754045
8.

Aortic cholesterol accumulation correlates with systemic inflammation but not hepatic and gonadal adipose tissue inflammation in low-density lipoprotein receptor null mice.

Wang S, Miller B, Matthan NR, Goktas Z, Wu D, Reed DB, Yin X, Grammas P, Moustaid-Moussa N, Shen CL, Lichtenstein AH.

Nutr Res. 2013 Dec;33(12):1072-82. doi: 10.1016/j.nutres.2013.09.002.

9.

Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity.

Błachnio-Zabielska A, Zabielski P, Baranowski M, Gorski J.

Lipids. 2011 Mar;46(3):229-38. doi: 10.1007/s11745-010-3515-z. Epub 2010 Dec 22.

10.

Sphingolipids and hepatic steatosis.

Bikman BT, Summers SA.

Adv Exp Med Biol. 2011;721:87-97. doi: 10.1007/978-1-4614-0650-1_6. Review.

PMID:
21910084
11.

Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression.

Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M.

FASEB J. 2011 Apr;25(4):1133-44. doi: 10.1096/fj.10-168351. Epub 2010 Dec 16.

12.

Cholesterol-induced hepatic inflammation does not contribute to the development of insulin resistance in male LDL receptor knockout mice.

Funke A, Schreurs M, Aparicio-Vergara M, Sheedfar F, Gruben N, Kloosterhuis NJ, Shiri-Sverdlov R, Groen AK, van de Sluis B, Hofker MH, Koonen DP.

Atherosclerosis. 2014 Feb;232(2):390-6. doi: 10.1016/j.atherosclerosis.2013.11.074. Epub 2013 Dec 18.

13.

Vitamin E prevents the age-dependent and palmitate-induced disturbances of sphingolipid turnover in liver cells.

Babenko NA, Hassouneh LKh, Kharchenko VS, Garkavenko VV.

Age (Dordr). 2012 Aug;34(4):905-15. doi: 10.1007/s11357-011-9288-3. Epub 2011 Jul 28.

14.

Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance.

Mulvihill EE, Allister EM, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Markle JM, Hegele RA, Huff MW.

Diabetes. 2009 Oct;58(10):2198-210. doi: 10.2337/db09-0634. Epub 2009 Jul 10.

15.

Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice.

Karavia EA, Papachristou DJ, Kotsikogianni I, Giopanou I, Kypreos KE.

FEBS J. 2011 Sep;278(17):3119-29. doi: 10.1111/j.1742-4658.2011.08238.x. Epub 2011 Aug 2.

16.

Autophagy regulates sphingolipid levels in the liver.

Alexaki A, Gupta SD, Majumder S, Kono M, Tuymetova G, Harmon JM, Dunn TM, Proia RL.

J Lipid Res. 2014 Dec;55(12):2521-31. doi: 10.1194/jlr.M051862. Epub 2014 Oct 20.

17.

Effects of Mycoplasma pneumoniae infection on sphingolipid metabolism in human lung carcinoma A549 cells.

Yu Y, Sun G, Liu G, Wang Y, Shao Z, Chen Z, Yang J.

Microb Pathog. 2009 Feb;46(2):63-72. doi: 10.1016/j.micpath.2008.10.014. Epub 2008 Nov 24.

PMID:
19059331
18.

Liver acid sphingomyelinase inhibits growth of metastatic colon cancer.

Osawa Y, Suetsugu A, Matsushima-Nishiwaki R, Yasuda I, Saibara T, Moriwaki H, Seishima M, Kozawa O.

J Clin Invest. 2013 Feb;123(2):834-43. doi: 10.1172/JCI65188. Epub 2013 Jan 9.

19.

Dietary fat-induced alterations in atherosclerosis are abolished by ACAT2-deficiency in ApoB100 only, LDLr-/- mice.

Bell TA 3rd, Kelley K, Wilson MD, Sawyer JK, Rudel LL.

Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1396-402. Epub 2007 Apr 12.

20.

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.

J Appl Physiol (1985). 2006 May;100(5):1467-74. Epub 2005 Dec 15.

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