Similar articles for PMID: 19071109

Year	Number of Results
1987	1
2003	1
2004	4
2005	11
2006	26
2007	34
2008	56
2009	34
2010	19
2011	24
2012	29
2013	22
2014	17
2015	21
2016	13
2017	8
2018	14
2019	7
2020	6
2021	5
2022	6
2023	1
2024	0

1

The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma.

Baumann P, Mandl-Weber S, Oduncu F, Schmidmaier R. Baumann P, et al. Exp Cell Res. 2009 Feb 1;315(3):485-97. doi: 10.1016/j.yexcr.2008.11.007. Epub 2008 Nov 27. Exp Cell Res. 2009. PMID: 19071109

2

Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.

McMillin DW, Ooi M, Delmore J, Negri J, Hayden P, Mitsiades N, Jakubikova J, Maira SM, Garcia-Echeverria C, Schlossman R, Munshi NC, Richardson PG, Anderson KC, Mitsiades CS. McMillin DW, et al. Cancer Res. 2009 Jul 15;69(14):5835-42. doi: 10.1158/0008-5472.CAN-08-4285. Epub 2009 Jul 7. Cancer Res. 2009. PMID: 19584292

3

Simultaneous targeting of PI3K and mTOR with NVP-BGT226 is highly effective in multiple myeloma.

Baumann P, Schneider L, Mandl-Weber S, Oduncu F, Schmidmaier R. Baumann P, et al. Anticancer Drugs. 2012 Jan;23(1):131-8. doi: 10.1097/CAD.0b013e32834c8683. Anticancer Drugs. 2012. PMID: 21959532

4

Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001.

Baumann P, Hagemeier H, Mandl-Weber S, Franke D, Schmidmaier R. Baumann P, et al. Anticancer Drugs. 2009 Apr;20(4):259-66. doi: 10.1097/CAD.0b013e328328d18b. Anticancer Drugs. 2009. PMID: 19240643

5

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, Botero ML, Llonch E, Atzori F, Di Cosimo S, Maira M, Garcia-Echeverria C, Parra JL, Arribas J, Baselga J. Serra V, et al. Cancer Res. 2008 Oct 1;68(19):8022-30. doi: 10.1158/0008-5472.CAN-08-1385. Cancer Res. 2008. PMID: 18829560

6

The dual PI3K and mTOR inhibitor NVP-BEZ235 exhibits anti-proliferative activity and overcomes bortezomib resistance in mantle cell lymphoma cells.

Kim A, Park S, Lee JE, Jang WS, Lee SJ, Kang HJ, Lee SS. Kim A, et al. Leuk Res. 2012 Jul;36(7):912-20. doi: 10.1016/j.leukres.2012.02.010. Epub 2012 May 5. Leuk Res. 2012. PMID: 22560334

7

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.

Chiarini F, Grimaldi C, Ricci F, Tazzari PL, Evangelisti C, Ognibene A, Battistelli M, Falcieri E, Melchionda F, Pession A, Pagliaro P, McCubrey JA, Martelli AM. Chiarini F, et al. Cancer Res. 2010 Oct 15;70(20):8097-107. doi: 10.1158/0008-5472.CAN-10-1814. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876803

8

NVP-BEZ235 as a new therapeutic option for sarcomas.

Manara MC, Nicoletti G, Zambelli D, Ventura S, Guerzoni C, Landuzzi L, Lollini PL, Maira SM, García-Echeverría C, Mercuri M, Picci P, Scotlandi K. Manara MC, et al. Clin Cancer Res. 2010 Jan 15;16(2):530-40. doi: 10.1158/1078-0432.CCR-09-0816. Epub 2010 Jan 12. Clin Cancer Res. 2010. PMID: 20068094

9

Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.

Zitzmann K, Rüden Jv, Brand S, Göke B, Lichtl J, Spöttl G, Auernhammer CJ. Zitzmann K, et al. Cancer Lett. 2010 Sep 1;295(1):100-9. doi: 10.1016/j.canlet.2010.02.018. Epub 2010 Mar 30. Cancer Lett. 2010. PMID: 20356670

10

Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells.

Baumann P, Mandl-Weber S, Emmerich B, Straka C, Schmidmaier R. Baumann P, et al. Exp Cell Res. 2007 Oct 1;313(16):3592-603. doi: 10.1016/j.yexcr.2007.06.020. Epub 2007 Jul 4. Exp Cell Res. 2007. PMID: 17669398

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