Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 387

1.

Synthesis of novel 3-(aryl)benzothieno[2,3-c]pyran-1-ones from Sonogashira products and intramolecular cyclization: Antitumoral activity evaluation.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2009 May;44(5):1893-9. doi: 10.1016/j.ejmech.2008.11.002. Epub 2008 Nov 13.

PMID:
19070942
2.

Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation.

Queiroz MJ, Abreu AS, Carvalho MS, Ferreira PM, Nazareth N, São-José Nascimento M.

Bioorg Med Chem. 2008 May 15;16(10):5584-9. doi: 10.1016/j.bmc.2008.04.004. Epub 2008 Apr 6.

PMID:
18439831
3.

Anti-tumor and anti-leishmanial evaluations of 1,3,4-oxadiazine, pyran derivatives derived from cross-coupling reactions of β-bromo-6H-1,3,4-oxadiazine derivatives.

Mohareb RM, Schatz J.

Bioorg Med Chem. 2011 Apr 15;19(8):2707-13. doi: 10.1016/j.bmc.2011.02.051. Epub 2011 Mar 4.

PMID:
21435889
4.

Hemisynthetic secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro.

Moiteiro C, Manta C, Justino F, Tavares R, Curto MJ, Pedro M, Nascimento MS, Pinto M.

J Nat Prod. 2004 Jul;67(7):1193-6.

PMID:
15270581
5.

Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: synthesis and antitumoral activities.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2010 Dec;45(12):5732-8. doi: 10.1016/j.ejmech.2010.09.030. Epub 2010 Sep 17.

PMID:
20934235
6.
7.

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH.

Eur J Med Chem. 2010 Dec;45(12):5628-34. doi: 10.1016/j.ejmech.2010.09.014. Epub 2010 Sep 17.

PMID:
20926160
8.

Synthesis of tetrahydronaphthalene lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition of human tumor cell lines.

Pinto O, Sardinha J, Vaz PD, Piedade F, Calhorda MJ, Abramovitch R, Nazareth N, Pinto M, Nascimento MS, Rauter AP.

J Med Chem. 2011 May 12;54(9):3175-87. doi: 10.1021/jm101182s. Epub 2011 Apr 19.

PMID:
21504224
9.

Synthesis and in vitro antitumoral activity of new N-phenyl-3-pyrrolecarbothioamides.

Cocco MT, Congiu C, Onnis V.

Bioorg Med Chem. 2003 Feb 20;11(4):495-503.

PMID:
12538014
10.

Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-activity relationships, effects on the cell cycle and apoptosis.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH.

Eur J Med Chem. 2011 Jan;46(1):236-40. doi: 10.1016/j.ejmech.2010.11.009. Epub 2010 Dec 8.

PMID:
21138784
11.
12.

Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions.

McCarroll AJ, Bradshaw TD, Westwell AD, Matthews CS, Stevens MF.

J Med Chem. 2007 Apr 5;50(7):1707-10. Epub 2007 Mar 8.

PMID:
17343370
13.

Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Kousidou OCh, Tzanakakis GN, Karamanos NK.

Eur J Med Chem. 2007 Mar;42(3):307-19. Epub 2006 Dec 4.

PMID:
17145121
14.

Thieno[3,2-c]pyran-4-one based novel small molecules: their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents.

Nakhi A, Adepu R, Rambabu D, Kishore R, Vanaja GR, Kalle AM, Pal M.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4418-27. doi: 10.1016/j.bmcl.2012.04.109. Epub 2012 May 2.

PMID:
22632935
15.
16.

Uses of cyanoacetylhydrazine in heterocyclic synthesis: novel synthesis of pyrazole derivatives with anti-tumor activities.

Mohareb RM, El-Sayed NN, Abdelaziz MA.

Molecules. 2012 Jul 12;17(7):8449-63. doi: 10.3390/molecules17078449.

17.

Dihydroxyxanthones prenylated derivatives: synthesis, structure elucidation, and growth inhibitory activity on human tumor cell lines with improvement of selectivity for MCF-7.

Castanheiro RA, Pinto MM, Silva AM, Cravo SM, Gales L, Damas AM, Nazareth N, Nascimento MS, Eaton G.

Bioorg Med Chem. 2007 Sep 15;15(18):6080-8. Epub 2007 Jun 23.

PMID:
17614292
18.
19.

6-Bicycloaryl substituted (S)- and (R)-5,6-dihydro-2H-pyran-2-ones: asymmetric synthesis, and anti-proliferative properties.

Kasaplar P, Yilmazer O, Cağir A.

Bioorg Med Chem. 2009 Jan 1;17(1):311-8. doi: 10.1016/j.bmc.2008.10.069. Epub 2008 Nov 5.

PMID:
19022676
20.

3-methyl-2-(4-substituted phenyl)-4,5-dihydronaphtho[1,2-c]-pyrazoles: synthesis and in-vitro biological evaluation as antitumour agents.

Al-Saadi MS, Rostom SA, Faidallah HM.

Arch Pharm (Weinheim). 2008 Mar;341(3):181-90. doi: 10.1002/ardp.200700178.

PMID:
18214843

Supplemental Content

Support Center