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Items: 1 to 20 of 104

1.

E2F2 represses cell cycle regulators to maintain quiescence.

Infante A, Laresgoiti U, Fernández-Rueda J, Fullaondo A, Galán J, Díaz-Uriarte R, Malumbres M, Field SJ, Zubiaga AM.

Cell Cycle. 2008 Dec 15;7(24):3915-27. Epub 2008 Dec 10.

PMID:
19066456
2.

Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signaling.

Bueno MJ, Gómez de Cedrón M, Laresgoiti U, Fernández-Piqueras J, Zubiaga AM, Malumbres M.

Mol Cell Biol. 2010 Jun;30(12):2983-95. doi: 10.1128/MCB.01372-09. Epub 2010 Apr 19.

3.

Divergent siblings: E2F2 and E2F4 but not E2F1 and E2F3 induce DNA synthesis in cardiomyocytes without activation of apoptosis.

Ebelt H, Hufnagel N, Neuhaus P, Neuhaus H, Gajawada P, Simm A, Müller-Werdan U, Werdan K, Braun T.

Circ Res. 2005 Mar 18;96(5):509-17. Epub 2005 Feb 17.

4.

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.

Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G.

J Biol Chem. 2006 Nov 24;281(47):36124-31. Epub 2006 Sep 27.

5.

The E2F1-3 transcription factors are essential for cellular proliferation.

Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G.

Nature. 2001 Nov 22;414(6862):457-62.

PMID:
11719808
6.

Cell proliferation in the absence of E2F1-3.

Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G.

Dev Biol. 2011 Mar 1;351(1):35-45. doi: 10.1016/j.ydbio.2010.12.025. Epub 2010 Dec 23.

7.

Contrasting roles of E2F2 and E2F3 in endothelial cell growth and ischemic angiogenesis.

Zhou J, Cheng M, Wu M, Boriboun C, Jujo K, Xu S, Zhao TC, Tang YL, Kishore R, Qin G.

J Mol Cell Cardiol. 2013 Jul;60:68-71. doi: 10.1016/j.yjmcc.2013.04.009. Epub 2013 Apr 18.

8.
9.

E2f1-3 are critical for myeloid development.

Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G.

J Biol Chem. 2011 Feb 11;286(6):4783-95. doi: 10.1074/jbc.M110.182733. Epub 2010 Nov 28.

10.

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.

Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G.

Mol Cell Biol. 2007 Jan;27(1):65-78. Erratum in: Mol Cell Biol. 2012 May;32(9):1758.

11.

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.

Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G.

Nature. 2009 Dec 17;462(7275):930-4. doi: 10.1038/nature08677.

12.

Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2.

Chen Q, Hung FC, Fromm L, Overbeek PA.

Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4223-31.

PMID:
11095619
13.

Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity.

Murga M, Fernández-Capetillo O, Field SJ, Moreno B, Borlado LR, Fujiwara Y, Balomenos D, Vicario A, Carrera AC, Orkin SH, Greenberg ME, Zubiaga AM.

Immunity. 2001 Dec;15(6):959-70.

14.

Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.

Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15400-5. Epub 2007 Sep 19.

15.

Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.

Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G.

Nat Cell Biol. 2015 Aug;17(8):1036-48. doi: 10.1038/ncb3210. Epub 2015 Jul 20.

16.

Accelerated DNA replication in E2F1- and E2F2-deficient macrophages leads to induction of the DNA damage response and p21(CIP1)-dependent senescence.

Iglesias-Ara A, Zenarruzabeitia O, Fernandez-Rueda J, Sánchez-Tilló E, Field SJ, Celada A, Zubiaga AM.

Oncogene. 2010 Oct 14;29(41):5579-90. doi: 10.1038/onc.2010.296. Epub 2010 Aug 2.

PMID:
20676136
17.
18.

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.

Zhu JW, Field SJ, Gore L, Thompson M, Yang H, Fujiwara Y, Cardiff RD, Greenberg M, Orkin SH, DeGregori J.

Mol Cell Biol. 2001 Dec;21(24):8547-64.

19.
20.

Division and apoptosis of E2f-deficient retinal progenitors.

Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R.

Nature. 2009 Dec 17;462(7275):925-9. doi: 10.1038/nature08544.

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