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Items: 1 to 20 of 133


Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway.

Wang JT, Doong SL, Teng SC, Lee CP, Tsai CH, Chen MR.

J Virol. 2009 Feb;83(4):1856-69. doi: 10.1128/JVI.01099-08. Epub 2008 Dec 3.


Glycogen synthase kinase 3 negatively regulates IFN regulatory factor 3 transactivation through phosphorylation at its linker region.

Wang JT, Chang LS, Chen CJ, Doong SL, Chang CW, Chen MR.

Innate Immun. 2014 Jan;20(1):78-87. doi: 10.1177/1753425913485307. Epub 2013 May 17.


Epstein-Barr virus BGLF4 kinase downregulates NF-κB transactivation through phosphorylation of coactivator UXT.

Chang LS, Wang JT, Doong SL, Lee CP, Chang CW, Tsai CH, Yeh SW, Hsieh CY, Chen MR.

J Virol. 2012 Nov;86(22):12176-86. doi: 10.1128/JVI.01918-12. Epub 2012 Aug 29.


Epstein-Barr virus protein kinase BGLF4 targets the nucleus through interaction with nucleoporins.

Chang CW, Lee CP, Huang YH, Yang PW, Wang JT, Chen MR.

J Virol. 2012 Aug;86(15):8072-85. doi: 10.1128/JVI.01058-12. Epub 2012 May 23.


Characterization of Epstein-Barr virus BGLF4 kinase expression control at the transcriptional and translational levels.

Wang JT, Chuang YC, Chen KL, Lu CC, Doong SL, Cheng HH, Chen YL, Liu TY, Chang Y, Han CH, Yeh SW, Chen MR.

J Gen Virol. 2010 Sep;91(Pt 9):2186-96. doi: 10.1099/vir.0.019729-0. Epub 2010 May 5.


BGLF4 kinase modulates the structure and transport preference of the nuclear pore complex to facilitate nuclear import of Epstein-Barr virus lytic proteins.

Chang CW, Lee CP, Su MT, Tsai CH, Chen MR.

J Virol. 2015 Feb;89(3):1703-18. doi: 10.1128/JVI.02880-14. Epub 2014 Nov 19.


Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3.

Zhu H, Zheng C, Xing J, Wang S, Li S, Lin R, Mossman KL.

J Virol. 2011 Nov;85(21):11079-89. doi: 10.1128/JVI.05098-11. Epub 2011 Aug 10.


Herpes simplex virus 1 serine/threonine kinase US3 hyperphosphorylates IRF3 and inhibits beta interferon production.

Wang S, Wang K, Lin R, Zheng C.

J Virol. 2013 Dec;87(23):12814-27. doi: 10.1128/JVI.02355-13. Epub 2013 Sep 18.


Xeroderma pigmentosum C is involved in Epstein Barr virus DNA replication.

Lu CC, Chen YC, Wang JT, Yang PW, Chen MR.

J Gen Virol. 2007 Dec;88(Pt 12):3234-43.


Effect of phosphorylation on the transactivation activity of Epstein-Barr virus BMRF1, a major target of the viral BGLF4 kinase.

Yang PW, Chang SS, Tsai CH, Chao YH, Chen MR.

J Gen Virol. 2008 Apr;89(Pt 4):884-95. doi: 10.1099/vir.0.83546-0.


Epstein-Barr virus BGLF4 kinase induces disassembly of the nuclear lamina to facilitate virion production.

Lee CP, Huang YH, Lin SF, Chang Y, Chang YH, Takada K, Chen MR.

J Virol. 2008 Dec;82(23):11913-26. doi: 10.1128/JVI.01100-08. Epub 2008 Sep 24.


Epstein-Barr virus BGLF4 kinase induces premature chromosome condensation through activation of condensin and topoisomerase II.

Lee CP, Chen JY, Wang JT, Kimura K, Takemoto A, Lu CC, Chen MR.

J Virol. 2007 May;81(10):5166-80. Epub 2007 Mar 14.


Binding of Kaposi's sarcoma-associated herpesvirus K-bZIP to interferon-responsive factor 3 elements modulates antiviral gene expression.

Lefort S, Soucy-Faulkner A, Grandvaux N, Flamand L.

J Virol. 2007 Oct;81(20):10950-60. Epub 2007 Jul 25.


Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

Johnson J, Albarani V, Nguyen M, Goldman M, Willems F, Aksoy E.

J Biol Chem. 2007 May 18;282(20):15022-32. Epub 2007 Feb 12.


Feline Herpesvirus 1 US3 Blocks the Type I Interferon Signal Pathway by Targeting Interferon Regulatory Factor 3 Dimerization in a Kinase-Independent Manner.

Tian J, Liu Y, Liu X, Sun X, Zhang J, Qu L.

J Virol. 2018 May 29;92(12). pii: e00047-18. doi: 10.1128/JVI.00047-18. Print 2018 Jun 15.


Protein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4.

Zhu J, Liao G, Shan L, Zhang J, Chen MR, Hayward GS, Hayward SD, Desai P, Zhu H.

J Virol. 2009 May;83(10):5219-31. doi: 10.1128/JVI.02378-08. Epub 2009 Feb 25.


Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.

Civas A, Génin P, Morin P, Lin R, Hiscott J.

J Biol Chem. 2006 Feb 24;281(8):4856-66. Epub 2005 Dec 27.


Detection of Epstein-Barr virus BGLF4 protein kinase in virus replication compartments and virus particles.

Wang JT, Yang PW, Lee CP, Han CH, Tsai CH, Chen MR.

J Gen Virol. 2005 Dec;86(Pt 12):3215-25.


Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.

Zhang D, Su C, Zheng C.

J Virol. 2016 May 27;90(12):5824-5829. doi: 10.1128/JVI.00186-16. Print 2016 Jun 15.

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