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The KCNMB1 E65K variant is associated with reduced central pulse pressure in the community-based Framingham Offspring Cohort.

Kelley-Hedgepeth A, Peter I, Montefusco MC, Levy D, Benjamin EJ, Vasan RS, Mendelsohn ME, Housman D, Huggins GS, Mitchell GF.

J Hypertens. 2009 Jan;27(1):55-60. doi: 10.1097/HJH.0b013e328317c8ae.


Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk.

Sentí M, Fernández-Fernández JM, Tomás M, Vázquez E, Elosua R, Marrugat J, Valverde MA.

Circ Res. 2005 Dec 9;97(12):1360-5. Epub 2005 Nov 17.


Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.

Levy D, Larson MG, Benjamin EJ, Newton-Cheh C, Wang TJ, Hwang SJ, Vasan RS, Mitchell GF.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S3.


Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study.

Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D.

Hypertension. 2004 Jun;43(6):1239-45. Epub 2004 May 3.


Association between arterial stiffness and variations in oestrogen-related genes.

Peter I, Kelley-Hedgepeth A, Huggins GS, Housman DE, Mendelsohn ME, Vita JA, Vasan RS, Levy D, Benjamin EJ, Mitchell GF.

J Hum Hypertens. 2009 Oct;23(10):636-44. doi: 10.1038/jhh.2009.1. Epub 2009 Feb 5.


Single-nucleotide polymorphisms in vascular Ca2+-activated K+-channel genes and cardiovascular disease.

Köhler R.

Pflugers Arch. 2010 Jul;460(2):343-51. doi: 10.1007/s00424-009-0768-6. Epub 2009 Dec 31. Review.


The protective effect of KCNMB1 E65K against hypertension is restricted to blood pressure treatment with beta-blockade.

Kelley-Hedgepeth A, Peter I, Kip K, Montefusco M, Kogan S, Cox D, Ordovas J, Levy D, Reis S, Mendelsohn M, Housman D, Huggins G.

J Hum Hypertens. 2008 Jul;22(7):512-5. doi: 10.1038/jhh.2008.23. Epub 2008 Apr 17. No abstract available.


The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

Nielsen T, Burgdorf KS, Grarup N, Borch-Johnsen K, Hansen T, Jørgensen T, Pedersen O, Andersen G.

J Hypertens. 2008 Nov;26(11):2142-6. doi: 10.1097/HJH.0b013e32830b894a.


Gender-specific brachial artery blood pressure-independent relationship between pulse wave velocity and left ventricular mass index in a group of African ancestry.

Libhaber E, Woodiwiss AJ, Libhaber C, Maseko M, Majane OH, Makaula S, Dessein P, Essop MR, Sareli P, Norton GR.

J Hypertens. 2008 Aug;26(8):1619-28. doi: 10.1097/HJH.0b013e328302ca27.


Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study.

Thanassoulis G, Lyass A, Benjamin EJ, Larson MG, Vita JA, Levy D, Hamburg NM, Widlansky ME, O'Donnell CJ, Mitchell GF, Vasan RS.

Circulation. 2012 Jun 12;125(23):2836-43. doi: 10.1161/CIRCULATIONAHA.111.063933. Epub 2012 May 9.


KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST).

Beitelshees AL, Gong Y, Wang D, Schork NJ, Cooper-Dehoff RM, Langaee TY, Shriver MD, Sadee W, Knot HJ, Pepine CJ, Johnson JA; INVEST Investigators..

Pharmacogenet Genomics. 2007 Sep;17(9):719-29.


Single nucleotide polymorphism discovery and haplotype analysis of Ca2+-dependent K+ channel beta-1 subunit.

Gong Y, Beitelshees AL, Wessel J, Langaee TY, Schork NJ, Johnson JA.

Pharmacogenet Genomics. 2007 Apr;17(4):267-75.


Associations and clinical relevance of aortic-brachial artery stiffness mismatch, aortic reservoir function, and central pressure augmentation.

Schultz MG, Hughes AD, Davies JE, Sharman JE.

Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1225-33. doi: 10.1152/ajpheart.00317.2015. Epub 2015 Aug 14.


Central arterial pulse wave augmentation is greater in girls than boys, independent of height.

Ayer JG, Harmer JA, Marks GB, Avolio A, Celermajer DS.

J Hypertens. 2010 Feb;28(2):306-13. doi: 10.1097/HJH.0b013e3283332286.


Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study.

Mitchell GF, Guo CY, Kathiresan S, Vasan RS, Larson MG, Vita JA, Keyes MJ, Vyas M, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ.

Hypertension. 2007 Jun;49(6):1285-90. Epub 2007 Apr 2.


Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection.

Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF Jr, Vasan RS, Mitchell GF, Benjamin EJ.

Hypertension. 2008 Jun;51(6):1651-7. doi: 10.1161/HYPERTENSIONAHA.107.105668. Epub 2008 Apr 21.


Forearm vascular reactivity and arterial stiffness in asymptomatic adults from the community.

Malik AR, Kondragunta V, Kullo IJ.

Hypertension. 2008 Jun;51(6):1512-8. doi: 10.1161/HYPERTENSIONAHA.107.106088. Epub 2008 Apr 21.


Circulating vascular growth factors and central hemodynamic load in the community.

Zachariah JP, Xanthakis V, Larson MG, Vita JA, Sullivan LM, Smith HM, Safa R, Peng X, Hamburg N, Levy D, Sawyer DB, Mitchell GF, Vasan RS.

Hypertension. 2012 Apr;59(4):773-9. doi: 10.1161/HYPERTENSIONAHA.111.179242. Epub 2012 Feb 27.

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