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Items: 1 to 20 of 132

1.

Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane.

Schmidt D, MacKinnon R.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19276-81. doi: 10.1073/pnas.0810187105. Epub 2008 Dec 2.

2.

A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers.

Schmidt D, Cross SR, MacKinnon R.

J Mol Biol. 2009 Jul 31;390(5):902-12. doi: 10.1016/j.jmb.2009.05.062. Epub 2009 May 27.

3.
4.

Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.

Sokolov S, Kraus RL, Scheuer T, Catterall WA.

Mol Pharmacol. 2008 Mar;73(3):1020-8. Epub 2007 Dec 21.

5.
6.

Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers.

Tao X, MacKinnon R.

J Mol Biol. 2008 Sep 26;382(1):24-33. doi: 10.1016/j.jmb.2008.06.085. Epub 2008 Jul 7.

7.

Ion channels: gate expectations.

Garcia ML.

Nature. 2004 Jul 8;430(6996):153-5. No abstract available.

PMID:
15241399
8.

The interaction of spider gating modifier peptides with voltage-gated potassium channels.

Huang PT, Shiau YS, Lou KL.

Toxicon. 2007 Feb;49(2):285-92. Epub 2006 Sep 27. Review.

PMID:
17113615
9.

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels.

Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP.

Biochemistry. 2013 Oct 22;52(42):7439-48. doi: 10.1021/bi4006418. Epub 2013 Oct 7.

PMID:
24044413
10.

Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers.

Bemporad D, Sands ZA, Wee CL, Grottesi A, Sansom MS.

Biochemistry. 2006 Oct 3;45(39):11844-55.

PMID:
17002285
11.

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.

Lee SY, Banerjee A, MacKinnon R.

PLoS Biol. 2009 Mar 3;7(3):e47. doi: 10.1371/journal.pbio.1000047.

12.

Localization of the voltage-sensor toxin receptor on KvAP.

Ruta V, MacKinnon R.

Biochemistry. 2004 Aug 10;43(31):10071-9.

PMID:
15287735
13.

Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel.

Jung HJ, Lee JY, Kim SH, Eu YJ, Shin SY, Milescu M, Swartz KJ, Kim JI.

Biochemistry. 2005 Apr 26;44(16):6015-23.

PMID:
15835890
14.

KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels.

Rocheleau JM, Kobertz WR.

J Gen Physiol. 2008 Jan;131(1):59-68. Epub 2007 Dec 17.

15.

Opening the shaker K+ channel with hanatoxin.

Milescu M, Lee HC, Bae CH, Kim JI, Swartz KJ.

J Gen Physiol. 2013 Feb;141(2):203-16. doi: 10.1085/jgp.201210914.

16.

Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels.

Salari A, Vega BS, Milescu LS, Milescu M.

Sci Rep. 2016 Apr 5;6:23894. doi: 10.1038/srep23894.

17.

JZTX-XIII, a Kv channel gating modifier toxin from Chinese tarantula Chilobrachys jingzhao.

Yuan C, Liu Z, Hu W, Gao T, Liang S.

Toxicon. 2012 Feb;59(2):265-71. doi: 10.1016/j.toxicon.2011.11.021. Epub 2011 Dec 8.

PMID:
22155305
18.

Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.

Takahashi H, Kim JI, Min HJ, Sato K, Swartz KJ, Shimada I.

J Mol Biol. 2000 Mar 31;297(3):771-80.

PMID:
10731427
19.

Portability of paddle motif function and pharmacology in voltage sensors.

Alabi AA, Bahamonde MI, Jung HJ, Kim JI, Swartz KJ.

Nature. 2007 Nov 15;450(7168):370-5.

20.

Voltage-sensor activation with a tarantula toxin as cargo.

Phillips LR, Milescu M, Li-Smerin Y, Mindell JA, Kim JI, Swartz KJ.

Nature. 2005 Aug 11;436(7052):857-60.

PMID:
16094370

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