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Chemotherapy induces tumor clearance independent of apoptosis.

Guerriero JL, Ditsworth D, Fan Y, Zhao F, Crawford HC, Zong WX.

Cancer Res. 2008 Dec 1;68(23):9595-600. doi: 10.1158/0008-5472.CAN-08-2452.


DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity.

Guerriero JL, Ditsworth D, Catanzaro JM, Sabino G, Furie MB, Kew RR, Crawford HC, Zong WX.

J Immunol. 2011 Mar 15;186(6):3517-26. doi: 10.4049/jimmunol.1003267. Epub 2011 Feb 7.


Metronomic cyclophosphamide schedule-dependence of innate immune cell recruitment and tumor regression in an implanted glioma model.

Wu J, Waxman DJ.

Cancer Lett. 2014 Oct 28;353(2):272-80. doi: 10.1016/j.canlet.2014.07.033. Epub 2014 Jul 25.


[Cyclophosphamide-induced apoptosis of murine lymphosarcoma cells in vivo].

Kaledin VI, Nikolin VP, Ageeva TA, Timofeeva OA, Filipenko ML, Ronichevskaia GM, Morozkova TS, Popova NA, Baĭmak TIu.

Vopr Onkol. 2000;46(5):588-93. Russian.


YopJ-induced caspase-1 activation in Yersinia-infected macrophages: independent of apoptosis, linked to necrosis, dispensable for innate host defense.

Zheng Y, Lilo S, Mena P, Bliska JB.

PLoS One. 2012;7(4):e36019. doi: 10.1371/journal.pone.0036019. Epub 2012 Apr 26.


Tumor apoptosis induced by epoxide-containing piperazines, a new class of anti-cancer agents.

Eilon GF, Gu J, Slater LM, Hara K, Jacobs JW.

Cancer Chemother Pharmacol. 2000;45(3):183-91.


Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo.

Sun JG, Li H, Li X, Zeng X, Wu P, Fung KP, Liu FY.

Apoptosis. 2014 May;19(5):871-82. doi: 10.1007/s10495-014-0969-0.


Tumor biology: use of tiled images in conjunction with measurements of cellular proliferation and death in response to drug treatments.

Wexler EJ, Gravallese EM, Czerniak PM, Devenny JJ, Longtine J, Wong MK, Slee AM, Kerr JS.

Clin Cancer Res. 2000 Aug;6(8):3361-70.


Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer.

Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ.

Cancer Res. 2002 Jul 1;62(13):3868-75.


Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.

Wirth T, Kühnel F, Fleischmann-Mundt B, Woller N, Djojosubroto M, Rudolph KL, Manns M, Zender L, Kubicka S.

Cancer Res. 2005 Aug 15;65(16):7393-402.


Imperatorin induces Mcl-1 degradation to cooperatively trigger Bax translocation and Bak activation to suppress drug-resistant human hepatoma.

Li X, Zeng X, Sun J, Li H, Wu P, Fung KP, Liu F.

Cancer Lett. 2014 Jun 28;348(1-2):146-55. doi: 10.1016/j.canlet.2014.03.017. Epub 2014 Mar 28.


DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells.

Xu W, Cheng M, Lao Y, Wang X, Wu J, Zhou L, Zhang Y, Xu H, Xu N.

Biochem Biophys Res Commun. 2015 Feb 13;457(3):300-6. doi: 10.1016/j.bbrc.2014.12.104. Epub 2015 Jan 7.


The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.

Huang SM, Hsu PC, Chen MY, Li WS, More SV, Lu KT, Wang YC.

Int J Cancer. 2012 Aug 1;131(3):722-32. doi: 10.1002/ijc.26401. Epub 2011 Oct 20.


VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.

Doloff JC, Waxman DJ.

Cancer Res. 2012 Mar 1;72(5):1103-15. doi: 10.1158/0008-5472.CAN-11-3380. Epub 2012 Jan 11.


Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.

Liu F, Liu Q, Yang D, Bollag WB, Robertson K, Wu P, Liu K.

Cancer Res. 2011 Nov 1;71(21):6807-16. doi: 10.1158/0008-5472.CAN-11-1575. Epub 2011 Sep 12.


Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells.

Schwartz PS, Waxman DJ.

Mol Pharmacol. 2001 Dec;60(6):1268-79.


A survivin-mediated oncolytic adenovirus induces non-apoptotic cell death in lung cancer cells and shows antitumoral potential in vivo.

Li B, Liu X, Fan J, Qi R, Bo L, Gu J, Qian Q, Qian C, Liu X.

J Gene Med. 2006 Oct;8(10):1232-42.


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