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Items: 1 to 20 of 118

1.

Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.

Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F.

Nature. 2008 Nov 20;456(7220):350-6. doi: 10.1038/nature07413.

2.

Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex.

Ricci CG, Silveira RL, Rivalta I, Batista VS, Skaf MS.

Sci Rep. 2016 Jan 29;6:19940. doi: 10.1038/srep19940.

3.

Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution.

Bernardes A, Batista FA, de Oliveira Neto M, Figueira AC, Webb P, Saidemberg D, Palma MS, Polikarpov I.

PLoS One. 2012;7(2):e31852. doi: 10.1371/journal.pone.0031852. Epub 2012 Feb 21.

4.

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.

Rochel N, Ciesielski F, Godet J, Moman E, Roessle M, Peluso-Iltis C, Moulin M, Haertlein M, Callow P, Mély Y, Svergun DI, Moras D.

Nat Struct Mol Biol. 2011 May;18(5):564-70. doi: 10.1038/nsmb.2054. Epub 2011 Apr 10.

PMID:
21478865
5.

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex.

Lemkul JA, Lewis SN, Bassaganya-Riera J, Bevan DR.

PLoS One. 2015 May 8;10(5):e0123984. doi: 10.1371/journal.pone.0123984. eCollection 2015.

6.

An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements.

Temple KA, Cohen RN, Wondisford SR, Yu C, Deplewski D, Wondisford FE.

J Biol Chem. 2005 Feb 4;280(5):3529-40. Epub 2004 Nov 29.

7.

Effect of heterodimer partner RXRalpha on PPARgamma activation function-2 helix in solution.

Lu J, Chen M, Stanley SE, Li E.

Biochem Biophys Res Commun. 2008 Jan 4;365(1):42-6. Epub 2007 Oct 31.

8.

Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA.

Orlov I, Rochel N, Moras D, Klaholz BP.

EMBO J. 2012 Jan 18;31(2):291-300. doi: 10.1038/emboj.2011.445. Epub 2011 Dec 16.

9.

Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.

DiRenzo J, Söderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Hörlein A, Rosenfeld MG, Glass CK.

Mol Cell Biol. 1997 Apr;17(4):2166-76.

10.

Conserved amino acids in the ligand-binding and tau(i) domains of the peroxisome proliferator-activated receptor alpha are necessary for heterodimerization with RXR.

Gorla-Bajszczak A, Juge-Aubry C, Pernin A, Burger AG, Meier CA.

Mol Cell Endocrinol. 1999 Jan 25;147(1-2):37-47.

PMID:
10195690
11.

Synergistic effects of RXR alpha and PPAR gamma ligands to inhibit growth in human colon cancer cells--phosphorylated RXR alpha is a critical target for colon cancer management.

Yamazaki K, Shimizu M, Okuno M, Matsushima-Nishiwaki R, Kanemura N, Araki H, Tsurumi H, Kojima S, Weinstein IB, Moriwaki H.

Gut. 2007 Nov;56(11):1557-63. Epub 2007 Jun 29.

12.
14.

Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models.

Isakova A, Berset Y, Hatzimanikatis V, Deplancke B.

J Biol Chem. 2016 May 6;291(19):10293-306. doi: 10.1074/jbc.M115.691154. Epub 2016 Feb 24.

16.

The effect of antagonists on the conformational exchange of the retinoid X receptor alpha ligand-binding domain.

Lu J, Dawson MI, Hu QY, Xia Z, Dambacher JD, Ye M, Zhang XK, Li E.

Magn Reson Chem. 2009 Dec;47(12):1071-80. doi: 10.1002/mrc.2515.

17.

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators.

Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, Milburn MV, Rosenfeld MG, Glass CK.

Nature. 1998 Sep 10;395(6698):199-202.

PMID:
9744281
18.

Agonist ligands mediate the transcriptional response of nuclear receptor heterodimers through distinct stoichiometric assemblies with coactivators.

Pavlin MR, Brunzelle JS, Fernandez EJ.

J Biol Chem. 2014 Sep 5;289(36):24771-8. doi: 10.1074/jbc.M114.575423. Epub 2014 Jul 22.

19.

Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway.

Tsao WC, Wu HM, Chi KH, Chang YH, Lin WW.

Exp Cell Res. 2005 Mar 10;304(1):234-43. Epub 2004 Dec 10.

PMID:
15707588
20.

Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain.

Boerma LJ, Xia G, Qui C, Cox BD, Chalmers MJ, Smith CD, Lobo-Ruppert S, Griffin PR, Muccio DD, Renfrow MB.

J Biol Chem. 2014 Jan 10;289(2):814-26. doi: 10.1074/jbc.M113.476861. Epub 2013 Nov 1.

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