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Items: 1 to 20 of 98


Gene regulation in primates evolves under tissue-specific selection pressures.

Blekhman R, Oshlack A, Chabot AE, Smyth GK, Gilad Y.

PLoS Genet. 2008 Nov;4(11):e1000271. doi: 10.1371/journal.pgen.1000271. Epub 2008 Nov 21. Erratum in: PLoS Genet. 2009 Mar;5(3). doi: 10.1371/annotation/06105fdb-f0fa-4fe2-88d0-db9f6036509f.


Expression profiling in primates reveals a rapid evolution of human transcription factors.

Gilad Y, Oshlack A, Smyth GK, Speed TP, White KP.

Nature. 2006 Mar 9;440(7081):242-5.


Natural selection on gene expression.

Gilad Y, Oshlack A, Rifkin SA.

Trends Genet. 2006 Aug;22(8):456-61. Epub 2006 Jun 27. Review.


Sex-specific and lineage-specific alternative splicing in primates.

Blekhman R, Marioni JC, Zumbo P, Stephens M, Gilad Y.

Genome Res. 2010 Feb;20(2):180-9. doi: 10.1101/gr.099226.109. Epub 2009 Dec 15.


Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence.

Blekhman R, Perry GH, Shahbaz S, Fiehn O, Clark AG, Gilad Y.

Sci Rep. 2014 Jul 28;4:5809. doi: 10.1038/srep05809.


Rapid evolution and copy number variation of primate RHOXF2, an X-linked homeobox gene involved in male reproduction and possibly brain function.

Niu AL, Wang YQ, Zhang H, Liao CH, Wang JK, Zhang R, Che J, Su B.

BMC Evol Biol. 2011 Oct 12;11:298. doi: 10.1186/1471-2148-11-298.


Primate transcript and protein expression levels evolve under compensatory selection pressures.

Khan Z, Ford MJ, Cusanovich DA, Mitrano A, Pritchard JK, Gilad Y.

Science. 2013 Nov 29;342(6162):1100-4. doi: 10.1126/science.1242379. Epub 2013 Oct 17.


Rapid sequence and expression divergence suggest selection for novel function in primate-specific KRAB-ZNF genes.

Nowick K, Hamilton AT, Zhang H, Stubbs L.

Mol Biol Evol. 2010 Nov;27(11):2606-17. doi: 10.1093/molbev/msq157. Epub 2010 Jun 23.


Selective constraints in experimentally defined primate regulatory regions.

Gaffney DJ, Blekhman R, Majewski J.

PLoS Genet. 2008 Aug 15;4(8):e1000157. doi: 10.1371/journal.pgen.1000157.


Comparative primate genomics: the year of the chimpanzee.

Ruvolo M.

Curr Opin Genet Dev. 2004 Dec;14(6):650-6. Review.


Comparative RNA sequencing reveals substantial genetic variation in endangered primates.

Perry GH, Melsted P, Marioni JC, Wang Y, Bainer R, Pickrell JK, Michelini K, Zehr S, Yoder AD, Stephens M, Pritchard JK, Gilad Y.

Genome Res. 2012 Apr;22(4):602-10. doi: 10.1101/gr.130468.111. Epub 2011 Dec 29.


Comparative studies of gene expression and the evolution of gene regulation.

Romero IG, Ruvinsky I, Gilad Y.

Nat Rev Genet. 2012 Jun 18;13(7):505-16. doi: 10.1038/nrg3229. Review.


Mining the molecules that made our mind.

Pennisi E.

Science. 2006 Sep 29;313(5795):1908-11. No abstract available.


Gene expression differences among primates are associated with changes in a histone epigenetic modification.

Cain CE, Blekhman R, Marioni JC, Gilad Y.

Genetics. 2011 Apr;187(4):1225-34. doi: 10.1534/genetics.110.126177. Epub 2011 Feb 14.


Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection.

Shibata Y, Sheffield NC, Fedrigo O, Babbitt CC, Wortham M, Tewari AK, London D, Song L, Lee BK, Iyer VR, Parker SC, Margulies EH, Wray GA, Furey TS, Crawford GE.

PLoS Genet. 2012 Jun;8(6):e1002789. doi: 10.1371/journal.pgen.1002789. Epub 2012 Jun 28.


Adaptive evolution of SCML1 in primates, a gene involved in male reproduction.

Wu HH, Su B.

BMC Evol Biol. 2008 Jul 5;8:192. doi: 10.1186/1471-2148-8-192.


Transcription factors are targeted by differentially expressed miRNAs in primates.

Dannemann M, Prüfer K, Lizano E, Nickel B, Burbano HA, Kelso J.

Genome Biol Evol. 2012;4(4):552-64. doi: 10.1093/gbe/evs033. Epub 2012 Mar 27.


Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, Franz H, Weiss G, Lachmann M, Pääbo S.

Science. 2005 Sep 16;309(5742):1850-4. Epub 2005 Sep 1.


Evolutionary trajectories of primate genes involved in HIV pathogenesis.

Ortiz M, Guex N, Patin E, Martin O, Xenarios I, Ciuffi A, Quintana-Murci L, Telenti A.

Mol Biol Evol. 2009 Dec;26(12):2865-75. doi: 10.1093/molbev/msp197. Epub 2009 Sep 2.


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