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Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs.

Briot R, Frank JA, Uchida T, Lee JW, Calfee CS, Matthay MA.

Chest. 2009 Feb;135(2):269-275. doi: 10.1378/chest.08-0919. Epub 2008 Nov 18.


Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs.

Frank JA, Briot R, Lee JW, Ishizaka A, Uchida T, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L52-9. Epub 2007 Mar 9.


Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome.

Jabaudon M, Blondonnet R, Roszyk L, Bouvier D, Audard J, Clairefond G, Fournier M, Marceau G, Déchelotte P, Pereira B, Sapin V, Constantin JM.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):191-9. doi: 10.1164/rccm.201501-0020OC.


Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury.

Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA.

Am J Respir Crit Care Med. 2006 May 1;173(9):1008-15. Epub 2006 Feb 2.


Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation.

McAuley DF, Curley GF, Hamid UI, Laffey JG, Abbott J, McKenna DH, Fang X, Matthay MA, Lee JW.

Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L809-15. doi: 10.1152/ajplung.00358.2013. Epub 2014 Feb 14.


Dietary advanced glycation end-products, its pulmonary receptor, and high mobility group box 1 in aspiration lung injury.

Smit PJ, Guo WA, Davidson BA, Mullan BA, Helinski JD, Knight PR 3rd.

J Surg Res. 2014 Sep;191(1):214-23. doi: 10.1016/j.jss.2014.04.001. Epub 2014 Apr 8.


Alveolar fluid clearance is faster in women with acute lung injury compared to men.

Bastarache JA, Ong T, Matthay MA, Ware LB.

J Crit Care. 2011 Jun;26(3):249-56. doi: 10.1016/j.jcrc.2010.06.005. Epub 2010 Aug 4.


Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury.

Deng W, Li CY, Tong J, Zhang W, Wang DX.

Respir Res. 2012 Mar 30;13:29. doi: 10.1186/1465-9921-13-29.


Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury.

Su X, Looney MR, Gupta N, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L1-5. doi: 10.1152/ajplung.90546.2008. Epub 2009 May 1.


The severity of shock is associated with impaired rates of net alveolar fluid clearance in clinical acute lung injury.

Zeyed YF, Bastarache JA, Matthay MA, Ware LB.

Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L550-5. doi: 10.1152/ajplung.00190.2012. Epub 2012 Jul 20.


Claudin-4 levels are associated with intact alveolar fluid clearance in human lungs.

Rokkam D, Lafemina MJ, Lee JW, Matthay MA, Frank JA.

Am J Pathol. 2011 Sep;179(3):1081-7. doi: 10.1016/j.ajpath.2011.05.017. Epub 2011 Jul 8.


How to measure alterations in alveolar barrier function as a marker of lung injury.

Herrero R, Matute-Bello G.

Curr Protoc Toxicol. 2015 Feb 2;63:24.3.1-15. doi: 10.1002/0471140856.tx2403s63.


IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism.

Roux J, McNicholas CM, Carles M, Goolaerts A, Houseman BT, Dickinson DA, Iles KE, Ware LB, Matthay MA, Pittet JF.

FASEB J. 2013 Mar;27(3):1095-106. doi: 10.1096/fj.12-219295. Epub 2012 Dec 6.


[Effect of recruitment maneuver on alveolar epithelium barrier in rat with acute lung injury].

Li N, Qiu HB, Yang Y, Guo FM, Chen YM, Li JQ, Sheng JF.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007 Feb;19(2):90-4. Chinese.


Alveolar but not intravenous S-ketamine inhibits alveolar sodium transport and lung fluid clearance in rats.

Berger MM, Pitzer B, Zügel S, Wieland CW, Vlaar AP, Schultz MJ, Dahan A, Bärtsch P, Hollmann MW, Mairbäurl H.

Anesth Analg. 2010 Jul;111(1):164-70. doi: 10.1213/ANE.0b013e3181e21cc9. Epub 2010 Jun 2.


Receptor for advanced glycation end-products regulates lung fluid balance via protein kinase C-gp91(phox) signaling to epithelial sodium channels.

Downs CA, Kreiner LH, Johnson NM, Brown LA, Helms MN.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):75-87. doi: 10.1165/rcmb.2014-0002OC.


Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation.

Calfee CS, Budev MM, Matthay MA, Church G, Brady S, Uchida T, Ishizaka A, Lara A, Ranes JL, deCamp MM, Arroliga AC.

J Heart Lung Transplant. 2007 Jul;26(7):675-80.


Alcohol worsens acute lung injury by inhibiting alveolar sodium transport through the adenosine A1 receptor.

Dada L, Gonzalez AR, Urich D, Soberanes S, Manghi TS, Chiarella SE, Chandel NS, Budinger GR, Mutlu GM.

PLoS One. 2012;7(1):e30448. doi: 10.1371/journal.pone.0030448. Epub 2012 Jan 17.


Increased claudin-3, -4 and -18 levels in bronchoalveolar lavage fluid reflect severity of acute lung injury.

Jin W, Rong L, Liu Y, Song Y, Li Y, Pan J.

Respirology. 2013 May;18(4):643-51. doi: 10.1111/resp.12034.


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