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Items: 1 to 20 of 392

1.

Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage.

Wilson PM, Fazzone W, LaBonte MJ, Lenz HJ, Ladner RD.

Nucleic Acids Res. 2009 Jan;37(1):78-95. doi: 10.1093/nar/gkn910. Epub 2008 Nov 16.

2.

The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis.

Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Tokunaga E, Oki E, Morita M, Kadomatsu K, Maehara Y, Kitao H.

Mol Cancer Ther. 2015 Oct;14(10):2332-42. doi: 10.1158/1535-7163.MCT-14-0748. Epub 2015 Jul 24.

3.

The role of dUTPase and uracil-DNA repair in cancer chemotherapy.

Ladner RD.

Curr Protein Pept Sci. 2001 Dec;2(4):361-70. Review.

PMID:
12374095
4.

Inhibition of dUTPase induces synthetic lethality with thymidylate synthase-targeted therapies in non-small cell lung cancer.

Wilson PM, LaBonte MJ, Lenz HJ, Mack PC, Ladner RD.

Mol Cancer Ther. 2012 Mar;11(3):616-28. doi: 10.1158/1535-7163.MCT-11-0781. Epub 2011 Dec 15.

5.

Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1.

Kolomeichuk SN, Bene A, Upreti M, Dennis RA, Lyle CS, Rajasekaran M, Chambers TC.

Mol Pharmacol. 2008 Jan;73(1):128-36. Erratum in: Mol Pharmacol. 2008 Aug;74(2):537.

6.

Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress.

Li J, Tan J, Zhuang L, Banerjee B, Yang X, Chau JF, Lee PL, Hande MP, Li B, Yu Q.

Cancer Res. 2007 Dec 1;67(23):11317-26. Erratum in: Cancer Res. 2008 Feb 1;68(3):956.

7.

Novel opportunities for thymidylate metabolism as a therapeutic target.

Wilson PM, Fazzone W, LaBonte MJ, Deng J, Neamati N, Ladner RD.

Mol Cancer Ther. 2008 Sep;7(9):3029-37. doi: 10.1158/1535-7163.MCT-08-0280.

8.

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, Owen LB, Liu X, Sladek FM.

Biochem J. 2006 Dec 1;400(2):303-13.

9.

T-oligo treatment decreases constitutive and UVB-induced COX-2 levels through p53- and NFkappaB-dependent repression of the COX-2 promoter.

Marwaha V, Chen YH, Helms E, Arad S, Inoue H, Bord E, Kishore R, Sarkissian RD, Gilchrest BA, Goukassian DA.

J Biol Chem. 2005 Sep 16;280(37):32379-88. Epub 2005 Jul 26.

10.
11.

DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression.

Wang YA, Kamarova Y, Shen KC, Jiang Z, Hahn MJ, Wang Y, Brooks SC.

Cancer Biol Ther. 2005 Oct;4(10):1138-43. Epub 2005 Oct 1.

PMID:
16131836
12.

The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells.

Allen WL, McLean EG, Boyer J, McCulla A, Wilson PM, Coyle V, Longley DB, Casero RA Jr, Johnston PG.

Mol Cancer Ther. 2007 Jan;6(1):128-37.

13.
14.

Microarray analysis of p53-dependent gene expression in response to hypoxia and DNA damage.

Corn PG, El-Deiry WS.

Cancer Biol Ther. 2007 Dec;6(12):1858-66. Epub 2007 Nov 20.

PMID:
18087215
15.

Identification of ANKRD11 as a p53 coactivator.

Neilsen PM, Cheney KM, Li CW, Chen JD, Cawrse JE, Schulz RB, Powell JA, Kumar R, Callen DF.

J Cell Sci. 2008 Nov 1;121(Pt 21):3541-52. doi: 10.1242/jcs.026351. Epub 2008 Oct 7.

16.

p53 upregulates death receptor 4 expression through an intronic p53 binding site.

Liu X, Yue P, Khuri FR, Sun SY.

Cancer Res. 2004 Aug 1;64(15):5078-83.

18.

Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells.

Liu PY, Chan JY, Lin HC, Wang SL, Liu ST, Ho CL, Chang LC, Huang SM.

Mol Cancer Res. 2008 Jul;6(7):1204-14. doi: 10.1158/1541-7786.MCR-08-0123.

19.

Tumor suppressor p53 represses transcription of RECQ4 helicase.

Sengupta S, Shimamoto A, Koshiji M, Pedeux R, Rusin M, Spillare EA, Shen JC, Huang LE, Lindor NM, Furuichi Y, Harris CC.

Oncogene. 2005 Mar 3;24(10):1738-48.

PMID:
15674334
20.

Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53.

Huang H, Kaku S, Knights C, Park B, Clifford J, Kulesz-Martin M.

Exp Cell Res. 2002 Oct 1;279(2):248-59.

PMID:
12243750

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