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Items: 1 to 20 of 312

1.

Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans.

Nes WD, Zhou W, Ganapathy K, Liu J, Vatsyayan R, Chamala S, Hernandez K, Miranda M.

Arch Biochem Biophys. 2009 Jan 15;481(2):210-8. doi: 10.1016/j.abb.2008.11.003.

PMID:
19014901
3.

Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans.

Vanden Bossche H, Marichal P, Le Jeune L, Coene MC, Gorrens J, Cools W.

Antimicrob Agents Chemother. 1993 Oct;37(10):2101-5.

7.

Metabolism of 24(R,S),25-epiminolanosterol to 25-aminolanosterol and lanosterol by Gibberella fujikuroi.

Nes WD, Xu SH, Parish EJ.

Arch Biochem Biophys. 1989 Aug 1;272(2):323-31.

PMID:
2751307
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11.

Purification, characterization and inhibition of sterol C24-methyltransferase from Candida albicans.

Ganapathy K, Kanagasabai R, Nguyen TT, Nes WD.

Arch Biochem Biophys. 2011 Jan 15;505(2):194-201. doi: 10.1016/j.abb.2010.10.008.

PMID:
20946868
12.

The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference.

Kaneshiro ES, Rosenfeld JA, Basselin-Eiweida M, Stringer JR, Keely SP, Smulian AG, Giner JL.

Mol Microbiol. 2002 May;44(4):989-99.

13.

Steroidal triterpenes: design of substrate-based inhibitors of ergosterol and sitosterol synthesis.

Liu J, Nes WD.

Molecules. 2009 Nov 18;14(11):4690-706. doi: doi:10.3390/molecules14114690. Review.

14.

Sterol composition in field-grown and cultured mycelia of Inonotus obliquus.

Zheng WF, Liu T, Xiang XY, Gu Q.

Yao Xue Xue Bao. 2007 Jul;42(7):750-6.

PMID:
17882960
15.

Cloning, mechanistic and functional analysis of a fungal sterol C24-methyltransferase implicated in brassicasterol biosynthesis.

Pereira M, Song Z, Santos-Silva LK, Richards MH, Nguyen TT, Liu J, de Almeida Soares CM, da Silva Cruz AH, Ganapathy K, Nes WD.

Biochim Biophys Acta. 2010 Oct;1801(10):1163-74. doi: 10.1016/j.bbalip.2010.06.007.

PMID:
20624480
16.

Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competence.

Howard AL, Liu J, Elmegeed GA, Collins EK, Ganatra KS, Nwogwugwu CA, Nes WD.

Arch Biochem Biophys. 2012 May;521(1-2):43-50. doi: 10.1016/j.abb.2012.03.002.

PMID:
22446159
17.

Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes.

Liendo A, Visbal G, Piras MM, Piras R, Urbina JA.

Mol Biochem Parasitol. 1999 Oct 25;104(1):81-91.

PMID:
10589983
18.

Nuclear demethylation and C-24 alkylation during ergosterol biosynthesis in Saccharomyces cerevisiae.

Fryberg M, Avruch L, Oehlschlager AC, Unrau AM.

Can J Biochem. 1975 Aug;53(8):881-9.

PMID:
1102069
20.

Regulation of sterol biosynthesis in sunflower by 24(R,S),25-epiminolanosterol, a novel C-24 methyl transferase inhibitor.

Nes WD, Janssen GG, Norton RA, Kalinowska M, Crumley FG, Tal B, Bergenstrahle A, Jonsson L.

Biochem Biophys Res Commun. 1991 May 31;177(1):566-74.

PMID:
2043140
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