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Items: 1 to 20 of 111


A structural basis for the recognition of 2'-deoxyguanosine by the purine riboswitch.

Edwards AL, Batey RT.

J Mol Biol. 2009 Jan 23;385(3):938-48. doi: 10.1016/j.jmb.2008.10.074. Epub 2008 Nov 5.


Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.

Gilbert SD, Stoddard CD, Wise SJ, Batey RT.

J Mol Biol. 2006 Jun 9;359(3):754-68. Epub 2006 Apr 21. Erratum in: J Mol Biol. 2006 Oct 20;363(2):624.


Mutational analysis of the purine riboswitch aptamer domain.

Gilbert SD, Love CE, Edwards AL, Batey RT.

Biochemistry. 2007 Nov 20;46(46):13297-309. Epub 2007 Oct 26.


Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.

Pikovskaya O, Polonskaia A, Patel DJ, Serganov A.

Nat Chem Biol. 2011 Aug 14;7(10):748-55. doi: 10.1038/nchembio.631.


Purine sensing by riboswitches.

Kim JN, Breaker RR.

Biol Cell. 2008 Jan;100(1):1-11. Review.


Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy.

Wacker A, Buck J, Mathieu D, Richter C, Wöhnert J, Schwalbe H.

Nucleic Acids Res. 2011 Aug;39(15):6802-12. doi: 10.1093/nar/gkr238. Epub 2011 May 16.


Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches.

Wacker A, Buck J, Richter C, Schwalbe H, Wöhnert J.

RNA Biol. 2012 May;9(5):672-80. doi: 10.4161/rna.20106. Epub 2012 May 1.


Guanine riboswitch variants from Mesoplasma florum selectively recognize 2'-deoxyguanosine.

Kim JN, Roth A, Breaker RR.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16092-7. Epub 2007 Oct 2.


Structural studies of the purine and SAM binding riboswitches.

Gilbert SD, Montange RK, Stoddard CD, Batey RT.

Cold Spring Harb Symp Quant Biol. 2006;71:259-68. Review.


Adaptive ligand binding by the purine riboswitch in the recognition of guanine and adenine analogs.

Gilbert SD, Reyes FE, Edwards AL, Batey RT.

Structure. 2009 Jun 10;17(6):857-68. doi: 10.1016/j.str.2009.04.009.


Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.

Serganov A, Yuan YR, Pikovskaya O, Polonskaia A, Malinina L, Phan AT, Hobartner C, Micura R, Breaker RR, Patel DJ.

Chem Biol. 2004 Dec;11(12):1729-41.


An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs.

Noeske J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, Wöhnert J.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1372-7. Epub 2005 Jan 21.


Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine.

Batey RT, Gilbert SD, Montange RK.

Nature. 2004 Nov 18;432(7015):411-5.


Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch.

Noeske J, Buck J, Fürtig B, Nasiri HR, Schwalbe H, Wöhnert J.

Nucleic Acids Res. 2007;35(2):572-83. Epub 2006 Dec 14.


Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.

Stagno JR, Liu Y, Bhandari YR, Conrad CE, Panja S, Swain M, Fan L, Nelson G, Li C, Wendel DR, White TA, Coe JD, Wiedorn MO, Knoska J, Oberthuer D, Tuckey RA, Yu P, Dyba M, Tarasov SG, Weierstall U, Grant TD, Schwieters CD, Zhang J, Ferré-D'Amaré AR, Fromme P, Draper DE, Liang M, Hunter MS, Boutet S, Tan K, Zuo X, Ji X, Barty A, Zatsepin NA, Chapman HN, Spence JC, Woodson SA, Wang YX.

Nature. 2017 Jan 12;541(7636):242-246. doi: 10.1038/nature20599. Epub 2016 Nov 14.


Riboswitch structures: purine ligands replace tertiary contacts.

Lescoute A, Westhof E.

Chem Biol. 2005 Jan;12(1):10-3. Review. No abstract available.


Structure and mechanism of purine-binding riboswitches.

Batey RT.

Q Rev Biophys. 2012 Aug;45(3):345-81. doi: 10.1017/S0033583512000078. Epub 2012 Jul 31. Review.


Modified pyrimidines specifically bind the purine riboswitch.

Gilbert SD, Mediatore SJ, Batey RT.

J Am Chem Soc. 2006 Nov 8;128(44):14214-5.


Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain.

Buck J, Wacker A, Warkentin E, Wöhnert J, Wirmer-Bartoschek J, Schwalbe H.

Nucleic Acids Res. 2011 Dec;39(22):9768-78. doi: 10.1093/nar/gkr664. Epub 2011 Sep 2.


Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch.

Villa A, Wöhnert J, Stock G.

Nucleic Acids Res. 2009 Aug;37(14):4774-86. doi: 10.1093/nar/gkp486. Epub 2009 Jun 10.

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