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Items: 1 to 20 of 103


HNF-1beta regulates transcription of the PKD modifier gene Kif12.

Gong Y, Ma Z, Patel V, Fischer E, Hiesberger T, Pontoglio M, Igarashi P.

J Am Soc Nephrol. 2009 Jan;20(1):41-7. doi: 10.1681/ASN.2008020238. Epub 2008 Nov 12.


Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.

Hiesberger T, Shao X, Gourley E, Reimann A, Pontoglio M, Igarashi P.

J Biol Chem. 2005 Mar 18;280(11):10578-86. Epub 2005 Jan 12.


Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.

Aboudehen K, Noureddine L, Cobo-Stark P, Avdulov S, Farahani S, Gearhart MD, Bichet DG, Pontoglio M, Patel V, Igarashi P.

J Am Soc Nephrol. 2017 Oct;28(10):2887-2900. doi: 10.1681/ASN.2016101095. Epub 2017 May 15.


Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.

Ma Z, Gong Y, Patel V, Karner CM, Fischer E, Hiesberger T, Carroll TJ, Pontoglio M, Igarashi P.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20386-91. Epub 2007 Dec 12.


Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.

Hiesberger T, Bai Y, Shao X, McNally BT, Sinclair AM, Tian X, Somlo S, Igarashi P.

J Clin Invest. 2004 Mar;113(6):814-25.


Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA.

Hajarnis SS, Patel V, Aboudehen K, Attanasio M, Cobo-Stark P, Pontoglio M, Igarashi P.

J Biol Chem. 2015 Oct 9;290(41):24793-805. doi: 10.1074/jbc.M115.670646. Epub 2015 Aug 19.


Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter.

Williams SS, Cobo-Stark P, Hajarnis S, Aboudehen K, Shao X, Richardson JA, Patel V, Igarashi P.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F356-68. doi: 10.1152/ajprenal.00422.2013. Epub 2014 Jun 4.


Roles of HNF-1beta in kidney development and congenital cystic diseases.

Igarashi P, Shao X, McNally BT, Hiesberger T.

Kidney Int. 2005 Nov;68(5):1944-7. Review.


Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.

Aboudehen K, Kim MS, Mitsche M, Garland K, Anderson N, Noureddine L, Pontoglio M, Patel V, Xie Y, DeBose-Boyd R, Igarashi P.

J Am Soc Nephrol. 2016 Aug;27(8):2408-21. doi: 10.1681/ASN.2015060607. Epub 2015 Dec 28.


Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β.

Choi YH, McNally BT, Igarashi P.

Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F100-10. doi: 10.1152/ajprenal.00582.2012. Epub 2013 May 8.


A mitotic transcriptional switch in polycystic kidney disease.

Verdeguer F, Le Corre S, Fischer E, Callens C, Garbay S, Doyen A, Igarashi P, Terzi F, Pontoglio M.

Nat Med. 2010 Jan;16(1):106-10. doi: 10.1038/nm.2068. Epub 2009 Dec 6.


The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells.

Zhang Y, Wada J, Yasuhara A, Iseda I, Eguchi J, Fukui K, Yang Q, Yamagata K, Hiesberger T, Igarashi P, Zhang H, Wang H, Akagi S, Kanwar YS, Makino H.

PLoS One. 2007 May 2;2(5):e414.


Hnf-1β transcription factor is an early hif-1α-independent marker of epithelial hypoxia and controls renal repair.

Faguer S, Mayeur N, Casemayou A, Pageaud AL, Courtellemont C, Cartery C, Fournie GJ, Schanstra JP, Tack I, Bascands JL, Chauveau D.

PLoS One. 2013 May 21;8(5):e63585. doi: 10.1371/journal.pone.0063585. Print 2013.


Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1beta mutations.

Bingham C, Ellard S, Cole TR, Jones KE, Allen LI, Goodship JA, Goodship TH, Bakalinova-Pugh D, Russell GI, Woolf AS, Nicholls AJ, Hattersley AT.

Kidney Int. 2002 Apr;61(4):1243-51.


Mutations in hepatocyte nuclear factor-1beta and their related phenotypes.

Edghill EL, Bingham C, Ellard S, Hattersley AT.

J Med Genet. 2006 Jan;43(1):84-90. Epub 2005 Jun 1.


The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas.

Rausa F, Samadani U, Ye H, Lim L, Fletcher CF, Jenkins NA, Copeland NG, Costa RH.

Dev Biol. 1997 Dec 15;192(2):228-46.


Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.

Casemayou A, Fournel A, Bagattin A, Schanstra J, Belliere J, Decramer S, Marsal D, Gillet M, Chassaing N, Huart A, Pontoglio M, Knauf C, Bascands JL, Chauveau D, Faguer S.

J Am Soc Nephrol. 2017 Nov;28(11):3205-3217. doi: 10.1681/ASN.2016050508. Epub 2017 Jul 24.


Upregulation of HNF-1β during experimental acute kidney injury plays a crucial role in renal tubule regeneration.

Ogata K, Shimamura Y, Hamada K, Hisa M, Bun M, Okada N, Inoue K, Taniguchi Y, Ishihara M, Kagawa T, Horino T, Fujimoto S, Terada Y.

Am J Physiol Renal Physiol. 2012 Sep;303(5):F689-99. doi: 10.1152/ajprenal.00086.2012. Epub 2012 Jul 3.


Activation of nicotinamide N-methyltransferase gene promoter by hepatocyte nuclear factor-1beta in human papillary thyroid cancer cells.

Xu J, Capezzone M, Xu X, Hershman JM.

Mol Endocrinol. 2005 Feb;19(2):527-39. Epub 2004 Oct 14.


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