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Items: 1 to 20 of 94


Acute internalization of gap junctions in vascular endothelial cells in response to inflammatory mediator-induced G-protein coupled receptor activation.

Baker SM, Kim N, Gumpert AM, Segretain D, Falk MM.

FEBS Lett. 2008 Dec 10;582(29):4039-46. doi: 10.1016/j.febslet.2008.10.043. Epub 2008 Nov 4.


Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists.

Tencé M, Ezan P, Amigou E, Giaume C.

Cell Signal. 2012 Jan;24(1):86-98. doi: 10.1016/j.cellsig.2011.08.006. Epub 2011 Aug 18.


Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1.

Rhett JM, Jourdan J, Gourdie RG.

Mol Biol Cell. 2011 May;22(9):1516-28. doi: 10.1091/mbc.E10-06-0548. Epub 2011 Mar 16.


Double-membrane gap junction internalization requires the clathrin-mediated endocytic machinery.

Gumpert AM, Varco JS, Baker SM, Piehl M, Falk MM.

FEBS Lett. 2008 Aug 20;582(19):2887-92. doi: 10.1016/j.febslet.2008.07.024. Epub 2008 Jul 24.


Chronic endothelin exposure inhibits connexin43 expression in cultured cortical astroglia.

Rozyczka J, Figiel M, Engele J.

J Neurosci Res. 2005 Feb 1;79(3):303-9.


Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen.

Gilleron J, Fiorini C, Carette D, Avondet C, Falk MM, Segretain D, Pointis G.

J Cell Sci. 2008 Dec 15;121(Pt 24):4069-78. doi: 10.1242/jcs.033373. Epub 2008 Nov 25.


Thrombin inhibits intercellular calcium wave propagation in corneal endothelial cells by modulation of hemichannels and gap junctions.

D'hondt C, Ponsaerts R, Srinivas SP, Vereecke J, Himpens B.

Invest Ophthalmol Vis Sci. 2007 Jan;48(1):120-33.


Internalized gap junctions are degraded by autophagy.

Fong JT, Kells RM, Gumpert AM, Marzillier JY, Davidson MW, Falk MM.

Autophagy. 2012 May 1;8(5):794-811. doi: 10.4161/auto.19390. Epub 2012 May 1.


Accelerated internalization of junctional membrane proteins (connexin 43, N-cadherin and ZO-1) within endocytic vacuoles: an early event of DDT carcinogenicity.

Fiorini C, Gilleron J, Carette D, Valette A, Tilloy A, Chevalier S, Segretain D, Pointis G.

Biochim Biophys Acta. 2008 Jan;1778(1):56-67. Epub 2007 Sep 14.


The second PDZ domain of zonula occludens-1 is dispensable for targeting to connexin 43 gap junctions.

Hunter AW, Gourdie RG.

Cell Commun Adhes. 2008 May;15(1):55-63. doi: 10.1080/15419060802014370.


Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis.

Fong JT, Kells RM, Falk MM.

Mol Biol Cell. 2013 Sep;24(18):2834-48. doi: 10.1091/mbc.E13-02-0111. Epub 2013 Jul 24.


ZO-1 determines adherens and gap junction localization at intercalated disks.

Palatinus JA, O'Quinn MP, Barker RJ, Harris BS, Jourdan J, Gourdie RG.

Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H583-94. doi: 10.1152/ajpheart.00999.2010. Epub 2010 Dec 3.


Distinct pharmacological properties of ET-1 and ET-3 on astroglial gap junctions and Ca(2+) signaling.

Blomstrand F, Giaume C, Hansson E, Rönnbäck L.

Am J Physiol. 1999 Oct;277(4 Pt 1):C616-27.


A proposed role for ZO-1 in targeting connexin 43 gap junctions to the endocytic pathway.

Segretain D, Fiorini C, Decrouy X, Defamie N, Prat JR, Pointis G.

Biochimie. 2004 Apr-May;86(4-5):241-4.


Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability.

Knezevic II, Predescu SA, Neamu RF, Gorovoy MS, Knezevic NM, Easington C, Malik AB, Predescu DN.

J Biol Chem. 2009 Feb 20;284(8):5381-94. doi: 10.1074/jbc.M808958200. Epub 2008 Dec 17.


Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process.

Piehl M, Lehmann C, Gumpert A, Denizot JP, Segretain D, Falk MM.

Mol Biol Cell. 2007 Feb;18(2):337-47. Epub 2006 Nov 15.


The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin.

Knezevic N, Tauseef M, Thennes T, Mehta D.

J Exp Med. 2009 Nov 23;206(12):2761-77. doi: 10.1084/jem.20090652. Epub 2009 Nov 16.


Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension.

Li J, Cao YX, Liu H, Xu CB.

Eur J Pharmacol. 2007 Feb 28;557(2-3):186-94. Epub 2006 Dec 1.


RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes.

Derangeon M, Bourmeyster N, Plaisance I, Pinet-Charvet C, Chen Q, Duthe F, Popoff MR, Sarrouilhe D, Hervé JC.

J Biol Chem. 2008 Nov 7;283(45):30754-65. doi: 10.1074/jbc.M801556200. Epub 2008 Jul 29.

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