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Items: 1 to 20 of 180

1.

New approaches to the treatment of inflammatory disease : focus on small-molecule inhibitors of signal transduction pathways.

Ivanenkov YA, Balakin KV, Tkachenko SE.

Drugs R D. 2008;9(6):397-434. doi: 10.2165/0126839-200809060-00005. Review.

PMID:
18989991
2.

Small molecule inhibitors of NF-kB and JAK/STAT signal transduction pathways as promising anti-inflammatory therapeutics.

Ivanenkov YA, Balakin KV, Lavrovsky Y.

Mini Rev Med Chem. 2011 Jan;11(1):55-78. Review.

PMID:
21034406
3.

Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway.

Ci X, Li H, Yu Q, Zhang X, Yu L, Chen N, Song Y, Deng X.

Fundam Clin Pharmacol. 2009 Aug;23(4):449-55. doi: 10.1111/j.1472-8206.2009.00684.x. Epub 2009 May 6.

PMID:
19453757
4.

Potential of flavonoids as anti-inflammatory agents: modulation of pro-inflammatory gene expression and signal transduction pathways.

Tuñón MJ, García-Mediavilla MV, Sánchez-Campos S, González-Gallego J.

Curr Drug Metab. 2009 Mar;10(3):256-71. Review.

PMID:
19442088
5.

New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

Peifer C, Wagner G, Laufer S.

Curr Top Med Chem. 2006;6(2):113-49. Review.

PMID:
16454763
6.
7.

Inhibition of transcription factors by plant-derived compounds and their implications in inflammation and cancer.

Ríos JL, Recio MC, Escandell JM, Andújar I.

Curr Pharm Des. 2009;15(11):1212-37. Review.

PMID:
19355962
8.
9.

Lucidone inhibits iNOS and COX-2 expression in LPS-induced RAW 264.7 murine macrophage cells via NF-kappaB and MAPKs signaling pathways.

Senthil Kumar KJ, Wang SY.

Planta Med. 2009 Apr;75(5):494-500. doi: 10.1055/s-0029-1185309. Epub 2009 Feb 4.

PMID:
19194838
10.

Flower extract of Panax notoginseng attenuates lipopolysaccharide-induced inflammatory response via blocking of NF-kappaB signaling pathway in murine macrophages.

Jung HW, Seo UK, Kim JH, Leem KH, Park YK.

J Ethnopharmacol. 2009 Mar 18;122(2):313-9. doi: 10.1016/j.jep.2008.12.024. Epub 2008 Dec 27.

PMID:
19162159
11.

Is there a future for small molecule drugs in the treatment of rheumatic diseases?

Stanczyk J, Ospelt C, Gay S.

Curr Opin Rheumatol. 2008 May;20(3):257-62. doi: 10.1097/BOR.0b013e3282fa13ee. Review.

12.

Regulation of MMP-9 gene expression for the development of novel molecular targets against cancer and inflammatory diseases.

St-Pierre Y, Couillard J, Van Themsche C.

Expert Opin Ther Targets. 2004 Oct;8(5):473-89. Review.

PMID:
15469396
13.

Signalling pathways mediating inflammatory responses in brain ischaemia.

Planas AM, Gorina R, Chamorro A.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1267-70. Review.

PMID:
17073799
14.

Pro-inflammatory cytokine-induced SAPK/MAPK and JAK/STAT in rheumatoid arthritis and the new anti-depression drugs.

Malemud CJ, Miller AH.

Expert Opin Ther Targets. 2008 Feb;12(2):171-83. doi: 10.1517/14728222.12.2.171 . Review.

PMID:
18208366
15.

Emerging drugs for asthma.

Walsh GM.

Expert Opin Emerg Drugs. 2008 Dec;13(4):643-53. doi: 10.1517/14728210802591378 . Review. Erratum in: Expert Opin Emerg Drugs. 2009 Mar;14(1):205.

PMID:
19046132
16.
17.

STAT1 as a new molecular target of anti-inflammatory treatment.

de Prati AC, Ciampa AR, Cavalieri E, Zaffini R, Darra E, Menegazzi M, Suzuki H, Mariotto S.

Curr Med Chem. 2005;12(16):1819-28. Review.

PMID:
16101503
18.

Novel targets for antiinflammatory and antiarthritic agents.

Kulkarni RG, Achaiah G, Sastry GN.

Curr Pharm Des. 2006;12(19):2437-54. Review.

PMID:
16842190
19.

Successful structure-based design of recent p38 MAP kinase inhibitors.

Karcher SC, Laufer SA.

Curr Top Med Chem. 2009;9(7):655-76. Review.

PMID:
19689372
20.

Signaling pathways associated with the expression of inflammatory mediators activated during the course of two models of experimental periodontitis.

Garcia de Aquino S, Manzolli Leite FR, Stach-Machado DR, Francisco da Silva JA, Spolidorio LC, Rossa C Jr.

Life Sci. 2009 May 22;84(21-22):745-54. doi: 10.1016/j.lfs.2009.03.001. Epub 2009 Mar 12.

PMID:
19285515

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