Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 72


HSV ICP0 recruits USP7 to modulate TLR-mediated innate response.

Daubeuf S, Singh D, Tan Y, Liu H, Federoff HJ, Bowers WJ, Tolba K.

Blood. 2009 Apr 2;113(14):3264-75. doi: 10.1182/blood-2008-07-168203. Epub 2008 Oct 24.


Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.

van Lint AL, Murawski MR, Goodbody RE, Severa M, Fitzgerald KA, Finberg RW, Knipe DM, Kurt-Jones EA.

J Virol. 2010 Oct;84(20):10802-11. doi: 10.1128/JVI.00063-10. Epub 2010 Aug 4.


Identification of a novel higher molecular weight isoform of USP7/HAUSP that interacts with the Herpes simplex virus type-1 immediate early protein ICP0.

Antrobus R, Boutell C.

Virus Res. 2008 Oct;137(1):64-71. doi: 10.1016/j.virusres.2008.05.017. Epub 2008 Jul 17.


Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1.

Pozhidaeva AK, Mohni KN, Dhe-Paganon S, Arrowsmith CH, Weller SK, Korzhnev DM, Bezsonova I.

J Biol Chem. 2015 Sep 18;290(38):22907-18. doi: 10.1074/jbc.M115.664805. Epub 2015 Jul 29.


Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response.

Conn KL, Wasson P, McFarlane S, Tong L, Brown JR, Grant KG, Domingues P, Boutell C.

J Virol. 2016 Apr 14;90(9):4807-4826. doi: 10.1128/JVI.03055-15. Print 2016 May.


Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.

Pfoh R, Lacdao IK, Georges AA, Capar A, Zheng H, Frappier L, Saridakis V.

PLoS Pathog. 2015 Jun 5;11(6):e1004950. doi: 10.1371/journal.ppat.1004950. eCollection 2015 Jun.


ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency.

Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM.

Virol J. 2006 Jun 9;3:44.


ICP0 dismantles microtubule networks in herpes simplex virus-infected cells.

Liu M, Schmidt EE, Halford WP.

PLoS One. 2010 Jun 8;5(6):e10975. doi: 10.1371/journal.pone.0010975.


A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7.

Canning M, Boutell C, Parkinson J, Everett RD.

J Biol Chem. 2004 Sep 10;279(37):38160-8. Epub 2004 Jul 6.


Herpes virus proteins ICP0 and BICP0 can activate NF-kappaB by catalyzing IkappaBalpha ubiquitination.

Diao L, Zhang B, Fan J, Gao X, Sun S, Yang K, Xin D, Jin N, Geng Y, Wang C.

Cell Signal. 2005 Feb;17(2):217-29.


The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

Cai M, Li M, Wang K, Wang S, Lu Q, Yan J, Mossman KL, Lin R, Zheng C.

PLoS One. 2013;8(1):e54586. doi: 10.1371/journal.pone.0054586. Epub 2013 Jan 28.


Protein tyrosine phosphatase with proline-glutamine-serine-threonine-rich motifs negatively regulates TLR-triggered innate responses by selectively inhibiting IκB kinase β/NF-κB activation.

Zhang P, Liu X, Li Y, Zhu X, Zhan Z, Meng J, Li N, Cao X.

J Immunol. 2013 Feb 15;190(4):1685-94. doi: 10.4049/jimmunol.1202384. Epub 2013 Jan 7.


The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.

Lilley CE, Chaurushiya MS, Boutell C, Everett RD, Weitzman MD.

PLoS Pathog. 2011 Jun;7(6):e1002084. doi: 10.1371/journal.ppat.1002084. Epub 2011 Jun 16.


Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling.

Tikhanovich I, Kuravi S, Artigues A, Villar MT, Dorko K, Nawabi A, Roberts B, Weinman SA.

J Biol Chem. 2015 Sep 4;290(36):22236-49. doi: 10.1074/jbc.M115.653543. Epub 2015 Jul 28.


Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L.

J Biol Chem. 2012 Mar 30;287(14):11002-10. doi: 10.1074/jbc.M111.328187. Epub 2012 Jan 19.


Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1.

Abe T, Barber GN.

J Virol. 2014 May;88(10):5328-41. doi: 10.1128/JVI.00037-14. Epub 2014 Mar 5.

Supplemental Content

Support Center