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Items: 1 to 20 of 132

1.

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

Muller AJ, Sharma MD, Chandler PR, Duhadaway JB, Everhart ME, Johnson BA 3rd, Kahler DJ, Pihkala J, Soler AP, Munn DH, Prendergast GC, Mellor AL.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17073-8. doi: 10.1073/pnas.0806173105. Epub 2008 Oct 24.

2.

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.

Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, Azuma M, Blazar BR, Mellor AL, Munn DH.

J Clin Invest. 2007 Sep;117(9):2570-82.

3.

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

Munn DH, Sharma MD, Hou D, Baban B, Lee JR, Antonia SJ, Messina JL, Chandler P, Koni PA, Mellor AL.

J Clin Invest. 2004 Jul;114(2):280-90. Erratum in: J Clin Invest. 2004 Aug;114(4):599.

4.

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

Sharma MD, Hou DY, Liu Y, Koni PA, Metz R, Chandler P, Mellor AL, He Y, Munn DH.

Blood. 2009 Jun 11;113(24):6102-11. doi: 10.1182/blood-2008-12-195354. Epub 2009 Apr 14.

5.

Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege.

Huang L, Baban B, Johnson BA 3rd, Mellor AL.

Int Rev Immunol. 2010 Apr;29(2):133-55. doi: 10.3109/08830180903349669. Review.

6.

Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion.

Muller AJ, DuHadaway JB, Chang MY, Ramalingam A, Sutanto-Ward E, Boulden J, Soler AP, Mandik-Nayak L, Gilmour SK, Prendergast GC.

Cancer Immunol Immunother. 2010 Nov;59(11):1655-63. doi: 10.1007/s00262-010-0891-4. Epub 2010 Jul 17.

7.

Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival.

Li J, Meinhardt A, Roehrich ME, Golshayan D, Dudler J, Pagnotta M, Trucco M, Vassalli G.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3415-23. Epub 2007 Oct 12.

8.

Constitutive expression of IDO by dendritic cells of mesenteric lymph nodes: functional involvement of the CTLA-4/B7 and CCL22/CCR4 interactions.

Onodera T, Jang MH, Guo Z, Yamasaki M, Hirata T, Bai Z, Tsuji NM, Nagakubo D, Yoshie O, Sakaguchi S, Takikawa O, Miyasaka M.

J Immunol. 2009 Nov 1;183(9):5608-14. doi: 10.4049/jimmunol.0804116.

9.

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.

Pallotta MT, Orabona C, Volpi C, Vacca C, Belladonna ML, Bianchi R, Servillo G, Brunacci C, Calvitti M, Bicciato S, Mazza EM, Boon L, Grassi F, Fioretti MC, Fallarino F, Puccetti P, Grohmann U.

Nat Immunol. 2011 Jul 31;12(9):870-8. doi: 10.1038/ni.2077.

PMID:
21804557
10.

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL.

Immunity. 2005 May;22(5):633-42.

11.

T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenase.

Kahler DJ, Mellor AL.

Handb Exp Pharmacol. 2009;(188):165-96. doi: 10.1007/978-3-540-71029-5_8. Review.

PMID:
19031026
12.

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity.

Lippens C, Duraes FV, Dubrot J, Brighouse D, Lacroix M, Irla M, Aubry-Lachainaye JP, Reith W, Mandl JN, Hugues S.

J Autoimmun. 2016 Dec;75:39-49. doi: 10.1016/j.jaut.2016.07.004. Epub 2016 Jul 26.

13.

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.

Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LM, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC.

Int Immunol. 2014 Jul;26(7):357-67. doi: 10.1093/intimm/dxt073. Epub 2014 Jan 8.

14.

Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression.

Colvin BL, Sumpter TL, Tokita D, Salati J, Mellor AL, Thomson AW.

Hum Immunol. 2009 May;70(5):313-20. doi: 10.1016/j.humimm.2009.01.021. Epub 2009 Feb 3.

15.

Leishmania major attenuates host immunity by stimulating local indoleamine 2,3-dioxygenase expression.

Makala LH, Baban B, Lemos H, El-Awady AR, Chandler PR, Hou DY, Munn DH, Mellor AL.

J Infect Dis. 2011 Mar 1;203(5):715-25. doi: 10.1093/infdis/jiq095. Epub 2011 Jan 31.

16.

Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT.

Ou X, Cai S, Liu P, Zeng J, He Y, Wu X, Du J.

J Cancer Res Clin Oncol. 2008 May;134(5):525-33. Epub 2007 Oct 2.

PMID:
17909857
17.

Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model.

Park MJ, Min SY, Park KS, Cho YG, Cho ML, Jung YO, Park HS, Chang SH, Cho SG, Min JK, Park SH, Kim HY.

Arthritis Res Ther. 2008;10(1):R11. doi: 10.1186/ar2361. Epub 2008 Jan 25.

18.

Indoleamine 2,3-dioxygenase: from catalyst to signaling function.

Fallarino F, Grohmann U, Puccetti P.

Eur J Immunol. 2012 Aug;42(8):1932-7. doi: 10.1002/eji.201242572. Review.

19.

Rosmarinic acid inhibits indoleamine 2,3-dioxygenase expression in murine dendritic cells.

Lee HJ, Jeong YI, Lee TH, Jung ID, Lee JS, Lee CM, Kim JI, Joo H, Lee JD, Park YM.

Biochem Pharmacol. 2007 May 1;73(9):1412-21. Epub 2006 Dec 20.

PMID:
17229401
20.

p-Coumaric acid inhibits indoleamine 2, 3-dioxygenase expression in murine dendritic cells.

Kim SI, Jeong YI, Jung ID, Lee JS, Lee CM, Yoon MS, Seong EY, Kim JI, Lee JD, Park YM.

Int Immunopharmacol. 2007 Jun;7(6):805-15. Epub 2007 Feb 27.

PMID:
17466914

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