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Items: 1 to 20 of 509

1.

Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.

Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G.

Bioorg Med Chem Lett. 2008 Dec 1;18(23):6175-8. doi: 10.1016/j.bmcl.2008.10.011. Epub 2008 Oct 7.

PMID:
18947996
2.

Design at the atomic level: generation of novel hybrid biaryloxazolidinones as promising new antibiotics.

Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G.

Bioorg Med Chem Lett. 2008 Dec 1;18(23):6179-83. doi: 10.1016/j.bmcl.2008.10.014. Epub 2008 Oct 7.

PMID:
18951792
3.

Synthesis and antibacterial activity of new N-linked 5-triazolylmethyl oxazolidinones.

Phillips OA, Udo EE, Ali AA, Samuel SM.

Bioorg Med Chem. 2005 Jun 2;13(12):4113-23. Epub 2005 Apr 25.

PMID:
15911326
4.

Novel oxazolidinone-quinolone hybrid antimicrobials.

Gordeev MF, Hackbarth C, Barbachyn MR, Banitt LS, Gage JR, Luehr GW, Gomez M, Trias J, Morin SE, Zurenko GE, Parker CN, Evans JM, White RJ, Patel DV.

Bioorg Med Chem Lett. 2003 Dec 1;13(23):4213-6.

PMID:
14623004
5.

Novel and potent oxazolidinone antibacterials featuring 3-indolylglyoxamide substituents.

Takhi M, Singh G, Murugan C, Thaplyyal N, Maitra S, Bhaskarreddy KM, Amarnath PV, Mallik A, Harisudan T, Trivedi RK, Sreenivas K, Selvakumar N, Iqbal J.

Bioorg Med Chem Lett. 2008 Sep 15;18(18):5150-5. doi: 10.1016/j.bmcl.2008.03.043. Epub 2008 Mar 20.

PMID:
18768315
6.

Synthesis and antibacterial activity of 5-substituted oxazolidinones.

Phillips OA, Udo EE, Ali AA, Al-Hassawi N.

Bioorg Med Chem. 2003 Jan 2;11(1):35-41.

PMID:
12467705
7.

Structure-activity relationship in the oxazolidinone-quinolone hybrid series: influence of the central spacer on the antibacterial activity and the mode of action.

Hubschwerlen C, Specklin JL, Baeschlin DK, Borer Y, Haefeli S, Sigwalt C, Schroeder S, Locher HH.

Bioorg Med Chem Lett. 2003 Dec 1;13(23):4229-33.

PMID:
14623007
8.

Carbon-carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria.

Lee CS, Allwine DA, Barbachyn MR, Grega KC, Dolak LA, Ford CW, Jensen RM, Seest EP, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Zurenko GE, Genin MJ.

Bioorg Med Chem. 2001 Dec;9(12):3243-53.

PMID:
11711300
9.

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones.

Paget SD, Foleno BD, Boggs CM, Goldschmidt RM, Hlasta DJ, Weidner-Wells MA, Werblood HM, Wira E, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2003 Dec 1;13(23):4173-7.

PMID:
14622996
10.

Effects of varied substituents on the antibacterial activity of triazolylmethyl oxazolidinones.

Phillips OA, Udo EE, Abdel-Hamid ME, Varghese R.

Arch Pharm (Weinheim). 2012 Oct;345(10):790-803. doi: 10.1002/ardp.201100332. Epub 2012 Aug 8.

PMID:
22886578
11.

Synthesis and antibacterial activity of some aryloxy/thioaryloxy oxazolidinone derivatives.

Arora V, Salunkhe MM, Sinha N, Sinha RK, Jain S.

Bioorg Med Chem Lett. 2004 Sep 20;14(18):4647-50.

PMID:
15324881
12.

Design, synthesis and biological evaluation of oxazolidinone-quinolone hybrids.

Hubschwerlen C, Specklin JL, Sigwalt C, Schroeder S, Locher HH.

Bioorg Med Chem. 2003 May 15;11(10):2313-9.

PMID:
12713843
13.

Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials.

Johnson PD, Aristoff PA, Zurenko GE, Schaadt RD, Yagi BH, Ford CW, Hamel JC, Stapert D, Moerman JK.

Bioorg Med Chem Lett. 2003 Dec 1;13(23):4197-200.

PMID:
14623000
14.

Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.

Genin MJ, Allwine DA, Anderson DJ, Barbachyn MR, Emmert DE, Garmon SA, Graber DR, Grega KC, Hester JB, Hutchinson DK, Morris J, Reischer RJ, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH.

J Med Chem. 2000 Mar 9;43(5):953-70.

PMID:
10715160
15.

Conformational constraint in oxazolidinone antibacterials. Synthesis and structure-activity studies of (azabicyclo[3.1.0]hexylphenyl)oxazolidinones.

Renslo AR, Jaishankar P, Venkatachalam R, Hackbarth C, Lopez S, Patel DV, Gordeev MF.

J Med Chem. 2005 Jul 28;48(15):5009-24.

PMID:
16033280
16.

The synthesis and antibacterial activity of 1,3,4-thiadiazole phenyl oxazolidinone analogues.

Thomasco LM, Gadwood RC, Weaver EA, Ochoada JM, Ford CW, Zurenko GE, Hamel JC, Stapert D, Moerman JK, Schaadt RD, Yagi BH.

Bioorg Med Chem Lett. 2003 Dec 1;13(23):4193-6.

PMID:
14622999
17.

Synthesis and antibacterial activity of novel (un)substituted benzotriazolyl oxazolidinone derivatives.

Dixit PP, Nair PS, Patil VJ, Jain S, Arora SK, Sinha N.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):3002-5.

PMID:
15908210
18.

Synthesis and antibacterial evaluation of isoxazolinyl oxazolidinones: Search for potent antibacterial.

Varshney V, Mishra NN, Shukla PK, Sahu DP.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3573-6. doi: 10.1016/j.bmcl.2009.04.133. Epub 2009 May 3.

PMID:
19447611
19.

Synthesis and antibacterial activities of eperezolid analogs with glycinyl substitutions.

Wang XJ, Wu N, Du GJ, Zhao SQ, Yan M, Gu LQ.

Arch Pharm (Weinheim). 2009 Jul;342(7):377-85. doi: 10.1002/ardp.200800233.

PMID:
19544480
20.

Synthesis and in vitro activity of novel 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinone antibacterial agents.

Khera MK, Cliffe IA, Mathur T, Prakash O.

Bioorg Med Chem Lett. 2011 May 15;21(10):2887-9. doi: 10.1016/j.bmcl.2011.03.075. Epub 2011 Mar 29.

PMID:
21507643
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