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Items: 1 to 20 of 254

1.

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

Shen S, Lang B, Nakamoto C, Zhang F, Pu J, Kuan SL, Chatzi C, He S, Mackie I, Brandon NJ, Marquis KL, Day M, Hurko O, McCaig CD, Riedel G, St Clair D.

J Neurosci. 2008 Oct 22;28(43):10893-904. doi: 10.1523/JNEUROSCI.3299-08.2008.

2.

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA.

Mol Psychiatry. 2008 Feb;13(2):173-86, 115. Epub 2007 Sep 11.

PMID:
17848917
3.

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development.

Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A.

Nat Cell Biol. 2005 Dec;7(12):1167-78. Epub 2005 Nov 20. Erratum in: Nat Cell Biol. 2006 Jan;8(1):100.

PMID:
16299498
4.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV.

Mol Psychiatry. 2011 Mar;16(3):293-306. doi: 10.1038/mp.2009.144. Epub 2010 Jan 5.

5.

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth.

Miyoshi K, Honda A, Baba K, Taniguchi M, Oono K, Fujita T, Kuroda S, Katayama T, Tohyama M.

Mol Psychiatry. 2003 Jul;8(7):685-94.

PMID:
12874605
6.

A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.

Hattori T, Baba K, Matsuzaki S, Honda A, Miyoshi K, Inoue K, Taniguchi M, Hashimoto H, Shintani N, Baba A, Shimizu S, Yukioka F, Kumamoto N, Yamaguchi A, Tohyama M, Katayama T.

Mol Psychiatry. 2007 Apr;12(4):398-407. Epub 2007 Jan 23.

PMID:
17389905
7.

Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans.

Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, Sawa A.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14501-6. Epub 2007 Aug 3.

8.

Gene models of schizophrenia: DISC1 mouse models.

Jaaro-Peled H.

Prog Brain Res. 2009;179:75-86. doi: 10.1016/S0079-6123(09)17909-8. Epub 2009 Nov 20. Review.

PMID:
20302820
9.

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder.

Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL.

Mol Psychiatry. 2005 Aug;10(8):758-64.

PMID:
15940305
10.

Phenotypic characterization of C57BL/6J mice carrying the Disc1 gene from the 129S6/SvEv strain.

Juan LW, Liao CC, Lai WS, Chang CY, Pei JC, Wong WR, Liu CM, Hwu HG, Lee LJ.

Brain Struct Funct. 2014 Jul;219(4):1417-31. doi: 10.1007/s00429-013-0577-8. Epub 2013 May 21.

PMID:
23689501
11.

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M.

Neuron. 2009 Sep 24;63(6):774-87. doi: 10.1016/j.neuron.2009.08.015.

12.

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders.

Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, Camargo LM, Oliver KR, Beher D, Shearman MS, Whiting PJ.

Mol Cell Neurosci. 2004 Jan;25(1):42-55.

PMID:
14962739
13.

Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice.

Lipina TV, Zai C, Hlousek D, Roder JC, Wong AH.

J Neurosci. 2013 May 1;33(18):7654-66. doi: 10.1523/JNEUROSCI.0091-13.2013.

14.

Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood.

Ibi D, Nagai T, Koike H, Kitahara Y, Mizoguchi H, Niwa M, Jaaro-Peled H, Nitta A, Yoneda Y, Nabeshima T, Sawa A, Yamada K.

Behav Brain Res. 2010 Jan 5;206(1):32-7. doi: 10.1016/j.bbr.2009.08.027. Epub 2009 Aug 28.

15.

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease.

Leliveld SR, Bader V, Hendriks P, Prikulis I, Sajnani G, Requena JR, Korth C.

J Neurosci. 2008 Apr 9;28(15):3839-45. doi: 10.1523/JNEUROSCI.5389-07.2008.

16.

Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour.

O'Tuathaigh CM, Babovic D, O'Meara G, Clifford JJ, Croke DT, Waddington JL.

Neurosci Biobehav Rev. 2007;31(1):60-78. Epub 2006 Jun 19. Review.

PMID:
16782199
17.

Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice.

Lee FH, Zai CC, Cordes SP, Roder JC, Wong AH.

Mol Brain. 2013 Apr 30;6:20. doi: 10.1186/1756-6606-6-20.

18.

Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling.

Canty AJ, Dietze J, Harvey M, Enomoto H, Milbrandt J, Ibáñez CF.

J Neurosci. 2009 Aug 26;29(34):10695-705. doi: 10.1523/JNEUROSCI.2658-09.2009.

19.

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Matsuzaki S, Tohyama M.

Neurochem Int. 2007 Jul-Sep;51(2-4):165-72. Epub 2007 Jun 27. Review.

PMID:
17664024
20.

DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain.

Austin CP, Ma L, Ky B, Morris JA, Shughrue PJ.

Neuroreport. 2003 May 23;14(7):951-4.

PMID:
12802181

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