Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 76

1.

The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission.

Dagda RK, Merrill RA, Cribbs JT, Chen Y, Hell JW, Usachev YM, Strack S.

J Biol Chem. 2008 Dec 26;283(52):36241-8. doi: 10.1074/jbc.M800989200. Epub 2008 Oct 21.

2.

N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.

Merrill RA, Slupe AM, Strack S.

FEBS J. 2013 Jan;280(2):662-73. doi: 10.1111/j.1742-4658.2012.08631.x. Epub 2012 Jun 8.

3.
4.

Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bbeta2).

Cheng WT, Guo ZX, Lin CA, Lin MY, Tung LC, Fang K.

BMC Cell Biol. 2009 Dec 18;10:91. doi: 10.1186/1471-2121-10-91.

5.
6.

Differential autophagic cell death under stress with ectopic cytoplasmic and mitochondrial-specific PPP2R2B in human neuroblastoma cells.

Fang K, Li HF, Hsieh CH, Li DY, Song DC, Cheng WT, Guo ZX.

Apoptosis. 2013 May;18(5):627-38. doi: 10.1007/s10495-013-0809-7.

PMID:
23381641
7.

Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12.

O'Hearn EE, Hwang HS, Holmes SE, Rudnicki DD, Chung DW, Seixas AI, Cohen RL, Ross CA, Trojanowski JQ, Pletnikova O, Troncoso JC, Margolis RL.

Mov Disord. 2015 Nov;30(13):1813-1824. doi: 10.1002/mds.26348. Epub 2015 Sep 4.

8.

PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics.

Dickey AS, Strack S.

J Neurosci. 2011 Nov 2;31(44):15716-26. doi: 10.1523/JNEUROSCI.3159-11.2011.

9.

Spinocerebellar ataxia type 12.

O'Hearn E, Holmes SE, Margolis RL.

Handb Clin Neurol. 2012;103:535-47. doi: 10.1016/B978-0-444-51892-7.00034-6. Review.

PMID:
21827912
10.

SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia.

Holmes SE, Hearn EO, Ross CA, Margolis RL.

Brain Res Bull. 2001 Oct-Nov 1;56(3-4):397-403. Review.

PMID:
11719278
11.

Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12).

Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, Su MT.

J Biol Chem. 2011 Jun 17;286(24):21742-54. doi: 10.1074/jbc.M110.160697. Epub 2011 Apr 6.

12.

A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function.

Ruvolo PP, Clark W, Mumby M, Gao F, May WS.

J Biol Chem. 2002 Jun 21;277(25):22847-52. Epub 2002 Apr 2.

13.

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death.

Grohm J, Plesnila N, Culmsee C.

Brain Behav Immun. 2010 Jul;24(5):831-8. doi: 10.1016/j.bbi.2009.11.015. Epub 2009 Dec 2.

PMID:
19961923
14.

Mapping of autosomal dominant cerebellar ataxia without the pathogenic PPP2R2B mutation to the locus for spinocerebellar ataxia 12.

Sato K, Yabe I, Fukuda Y, Soma H, Nakahara Y, Tsuji S, Sasaki H.

Arch Neurol. 2010 Oct;67(10):1257-62. doi: 10.1001/archneurol.2010.231.

PMID:
20937954
15.
16.

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.

Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M.

J Biol Chem. 2007 Dec 21;282(51):37006-15. Epub 2007 Oct 25.

17.

Protein phosphatase 2A facilitates axonogenesis by dephosphorylating CRMP2.

Zhu LQ, Zheng HY, Peng CX, Liu D, Li HL, Wang Q, Wang JZ.

J Neurosci. 2010 Mar 10;30(10):3839-48. doi: 10.1523/JNEUROSCI.5174-09.2010.

18.

Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.

Cao G, Xiao M, Sun F, Xiao X, Pei W, Li J, Graham SH, Simon RP, Chen J.

J Neurosci. 2004 Jul 7;24(27):6189-201.

20.

Identification of 46 CAG repeats within PPP2R2B as probably the shortest pathogenic allele for SCA12.

Dong Y, Wu JJ, Wu ZY.

Parkinsonism Relat Disord. 2015 Apr;21(4):398-401. doi: 10.1016/j.parkreldis.2015.01.006. Epub 2015 Jan 17.

PMID:
25634432

Supplemental Content

Support Center