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Polymorphisms in the interleukin-4 receptor gene are associated with better survival in patients with glioblastoma.

Scheurer ME, Amirian E, Cao Y, Gilbert MR, Aldape KD, Kornguth DG, El-Zein R, Bondy ML.

Clin Cancer Res. 2008 Oct 15;14(20):6640-6. doi: 10.1158/1078-0432.CCR-07-4681.


Polymorphism in the IL4R gene and clinical features are associated with glioma prognosis: Analyses of case-cohort studies.

Jin TB, Du S, Zhu XK, Li G, Ouyang Y, He N, Zhang Z, Zhang Y, Kang L, Yuan D.

Medicine (Baltimore). 2016 Aug;95(31):e4231. doi: 10.1097/MD.0000000000004231.


Allergy-related polymorphisms influence glioma status and serum IgE levels.

Wiemels JL, Wiencke JK, Kelsey KT, Moghadassi M, Rice T, Urayama KY, Miike R, Wrensch M.

Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1229-35.


Favorable impact of the interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial.

Schoof N, von Bonin F, Zeynalova S, Ziepert M, Jung W, Loeffler M, Pfreundschuh M, Trümper L, Kube D.

Ann Oncol. 2009 Sep;20(9):1548-54. doi: 10.1093/annonc/mdp110. Epub 2009 Jun 10.


Association and interaction of the IL4R, IL4, and IL13 loci with type 1 diabetes among Filipinos.

Bugawan TL, Mirel DB, Valdes AM, Panelo A, Pozzilli P, Erlich HA.

Am J Hum Genet. 2003 Jun;72(6):1505-14. Epub 2003 May 13.


Single nucleotide polymorphisms in IL-4Ra, IL-13 and STAT6 genes occurs in brain glioma.

Ruan Z, Zhao Y, Yan L, Chen H, Fan W, Chen J, Wu Q, Qian J, Zhang T, Zhou K, Mao Y, Zhou L, Huang Y, Lu D.

Front Biosci (Elite Ed). 2011 Jan 1;3:33-45.


Association between the polymorphisms of interleukin-4, the interleukin-4 receptor gene and asthma.

Zhu N, Gong Y, Chen XD, Zhang J, Long F, He J, Xia JW, Dong L.

Chin Med J (Engl). 2013;126(15):2943-51.


Impact of single nucleotide polymorphism in IL-4, IL-4R genes and systemic concentration of IL-4 on the incidence of glioma in Iraqi patients.

Shamran HA, Hamza SJ, Yaseen NY, Al-Juboory AA, Taub DD, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP.

Int J Med Sci. 2014 Aug 22;11(11):1147-53. doi: 10.7150/ijms.9412. eCollection 2014.


An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk.

Schwartzbaum JA, Ahlbom A, Lönn S, Malmer B, Wigertz A, Auvinen A, Brookes AJ, Collatz Christensen H, Henriksson R, Johansen C, Salminen T, Schoemaker MJ, Swerdlow AJ, Debinski W, Feychting M.

Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2448-54.


Association of IL4, IL13, and IL4R polymorphisms with gastrointestinal cancer risk: A meta-analysis.

Cho YA, Kim J.

J Epidemiol. 2017 May;27(5):215-220. doi: 10.1016/ Epub 2017 Jan 5.


Polymorphisms in IL-4/IL-13 pathway genes and glioma risk: an updated meta-analysis.

Chen P, Chen C, Chen K, Xu T, Luo C.

Tumour Biol. 2015 Jan;36(1):121-7. doi: 10.1007/s13277-014-2895-8. Epub 2014 Dec 4.


Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.

Namkung JH, Lee JE, Kim E, Kim HJ, Seo EY, Jang HY, Shin ES, Cho EY, Yang JM.

Exp Dermatol. 2011 Nov;20(11):915-9. doi: 10.1111/j.1600-0625.2011.01357.x. Epub 2011 Sep 14.


Cytokine gene polymorphisms in Tunisian endemic pemphigus foliaceus: a possible role of il-4 variants.

Toumi A, Abida O, Ben Ayed M, Masmoudi A, Turki H, Masmoudi H.

Hum Immunol. 2013 May;74(5):658-65. doi: 10.1016/j.humimm.2013.01.009. Epub 2013 Jan 29.


Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients.

Jacobs DI, Liu Y, Gabrusiewicz K, Tsavachidis S, Armstrong GN, Zhou R, Wei J, Ivan C, Calin G, Molinaro AM, Rice T, Bracci PM, Hansen HM, Wiencke JK, Wrensch MR, Heimberger AB, Bondy ML.

J Neurooncol. 2018 Jan;136(1):33-39. doi: 10.1007/s11060-017-2622-6. Epub 2017 Sep 30.


RTEL1 tagging SNPs and haplotypes were associated with glioma development.

Li G, Jin T, Liang H, Zhang Z, He S, Tu Y, Yang H, Geng T, Cui G, Chen C, Gao G.

Diagn Pathol. 2013 May 17;8:83. doi: 10.1186/1746-1596-8-83.


SSBP2 variants are associated with survival in glioblastoma patients.

Xiao Y, Decker PA, Rice T, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Wiemels JL, Tihan T, Prados MD, Chang SM, Berger MS, Kosel ML, Fridley BL, Lachance DH, O'Neill BP, Buckner JC, Thompson RC, Nabors LB, Olson JJ, Brem S, Madden MH, Browning JE, Wiencke JK, Egan KM, Jenkins RB, Wrensch MR.

Clin Cancer Res. 2012 Jun 1;18(11):3154-62. doi: 10.1158/1078-0432.CCR-11-2778. Epub 2012 Apr 3.


Analysis of IL4R haplotypes in predisposition to multiple sclerosis.

Mirel DB, Barcellos LF, Wang J, Hauser SL, Oksenberg JR, Erlich HA.

Genes Immun. 2004 Mar;5(2):138-41.


Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population.

Jin T, Li X, Zhang J, Wang H, Geng T, Li G, Gao G, Chen C.

BMC Cancer. 2013 May 12;13:236. doi: 10.1186/1471-2407-13-236.


A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma.

Permuth-Wey J, Thompson RC, Burton Nabors L, Olson JJ, Browning JE, Madden MH, Ann Chen Y, Egan KM.

J Neurooncol. 2011 Dec;105(3):639-46. doi: 10.1007/s11060-011-0634-1. Epub 2011 Jul 9.

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