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Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs.

Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R.

Genes Dev. 2008 Oct 15;22(20):2773-85. doi: 10.1101/gad.1705308.


Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues.

Castellano L, Stebbing J.

Nucleic Acids Res. 2013 Mar 1;41(5):3339-51. doi: 10.1093/nar/gks1474. Epub 2013 Jan 15.


DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal.

Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R.

Nat Genet. 2007 Mar;39(3):380-5. Epub 2007 Jan 28.


DGCR8-dependent microRNA biogenesis is essential for skin development.

Yi R, Pasolli HA, Landthaler M, Hafner M, Ojo T, Sheridan R, Sander C, O'Carroll D, Stoffel M, Tuschl T, Fuchs E.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):498-502. doi: 10.1073/pnas.0810766105. Epub 2008 Dec 29.


MicroRNA function is globally suppressed in mouse oocytes and early embryos.

Suh N, Baehner L, Moltzahn F, Melton C, Shenoy A, Chen J, Blelloch R.

Curr Biol. 2010 Feb 9;20(3):271-7. doi: 10.1016/j.cub.2009.12.044. Epub 2010 Jan 28.


Biogenesis of mammalian microRNAs by a non-canonical processing pathway.

Havens MA, Reich AA, Duelli DM, Hastings ML.

Nucleic Acids Res. 2012 May;40(10):4626-40. doi: 10.1093/nar/gks026. Epub 2012 Jan 23.


A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing.

Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R.

RNA. 2011 Aug;17(8):1489-501. doi: 10.1261/rna.2442211. Epub 2011 Jun 28.


Noncanonical microRNAs and endogenous siRNAs in lytic infection of murine gammaherpesvirus.

Xia J, Zhang W.

PLoS One. 2012;7(10):e47863. doi: 10.1371/journal.pone.0047863. Epub 2012 Oct 26.


Canonical and alternate functions of the microRNA biogenesis machinery.

Chong MM, Zhang G, Cheloufi S, Neubert TA, Hannon GJ, Littman DR.

Genes Dev. 2010 Sep 1;24(17):1951-60. doi: 10.1101/gad.1953310. Epub 2010 Aug 16. Erratum in: Genes Dev. 2010 Oct 1;24(19):2228.


Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing.

Lee HY, Zhou K, Smith AM, Noland CL, Doudna JA.

Nucleic Acids Res. 2013 Jul;41(13):6568-76. doi: 10.1093/nar/gkt361. Epub 2013 May 9.


Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8.

Shenoy A, Blelloch R.

PLoS One. 2009 Sep 11;4(9):e6971. doi: 10.1371/journal.pone.0006971.


Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.

Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15163-8. doi: 10.1073/pnas.1006432107. Epub 2010 Aug 10.


MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA, Surani MA.

PLoS One. 2008 Mar 5;3(3):e1738. doi: 10.1371/journal.pone.0001738.


Dicer-dependent biogenesis of small RNAs derived from 7SL RNA.

Ren YF, Li G, Wu J, Xue YF, Song YJ, Lv L, Zhang XJ, Tang KF.

PLoS One. 2012;7(7):e40705. doi: 10.1371/journal.pone.0040705. Epub 2012 Jul 12.


Noncanonical cytoplasmic processing of viral microRNAs.

Shapiro JS, Varble A, Pham AM, Tenoever BR.

RNA. 2010 Nov;16(11):2068-74. doi: 10.1261/rna.2303610. Epub 2010 Sep 14.


How short RNAs impact the human ribonuclease Dicer activity: putative regulatory feedback-loops and other RNA-mediated mechanisms controlling microRNA processing.

Koralewska N, Hoffmann W, Pokornowska M, Milewski M, Lipinska A, Bienkowska-Szewczyk K, Figlerowicz M, Kurzynska-Kokorniak A.

Acta Biochim Pol. 2016;63(4):773-783. Epub 2016 Oct 13.


The role of human Dicer-dsRBD in processing small regulatory RNAs.

Wostenberg C, Lary JW, Sahu D, Acevedo R, Quarles KA, Cole JL, Showalter SA.

PLoS One. 2012;7(12):e51829. doi: 10.1371/journal.pone.0051829. Epub 2012 Dec 13.


Global identification of target recognition and cleavage by the Microprocessor in human ES cells.

Seong Y, Lim DH, Kim A, Seo JH, Lee YS, Song H, Kwon YS.

Nucleic Acids Res. 2014 Nov 10;42(20):12806-21. doi: 10.1093/nar/gku957. Epub 2014 Oct 17.


Single processing center models for human Dicer and bacterial RNase III.

Zhang H, Kolb FA, Jaskiewicz L, Westhof E, Filipowicz W.

Cell. 2004 Jul 9;118(1):57-68.


Noncanonical microRNAs and endogenous siRNAs in normal and psoriatic human skin.

Xia J, Joyce CE, Bowcock AM, Zhang W.

Hum Mol Genet. 2013 Feb 15;22(4):737-48. doi: 10.1093/hmg/dds481. Epub 2012 Nov 21.

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