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Items: 1 to 20 of 116

1.

Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

Lau KF, Chan WM, Perkinton MS, Tudor EL, Chang RC, Chan HY, McLoughlin DM, Miller CC.

J Biol Chem. 2008 Dec 12;283(50):34728-37. doi: 10.1074/jbc.M801874200. Epub 2008 Oct 15.

2.

Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing.

Chow WN, Ngo JC, Li W, Chen YW, Tam KM, Chan HY, Miller CC, Lau KF.

Biochem J. 2015 Sep 15;470(3):303-17. doi: 10.1042/BJ20141485. Epub 2015 Jul 17.

3.

The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling.

Perkinton MS, Standen CL, Lau KF, Kesavapany S, Byers HL, Ward M, McLoughlin DM, Miller CC.

J Biol Chem. 2004 May 21;279(21):22084-91. Epub 2004 Mar 18.

4.

Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid.

Ando K, Iijima KI, Elliott JI, Kirino Y, Suzuki T.

J Biol Chem. 2001 Oct 26;276(43):40353-61. Epub 2001 Aug 21.

5.

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

Kim HS, Kim EM, Lee JP, Park CH, Kim S, Seo JH, Chang KA, Yu E, Jeong SJ, Chong YH, Suh YH.

FASEB J. 2003 Oct;17(13):1951-3. Epub 2003 Aug 15.

PMID:
12923068
6.
7.

Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration.

Chang KA, Kim HS, Ha TY, Ha JW, Shin KY, Jeong YH, Lee JP, Park CH, Kim S, Baik TK, Suh YH.

Mol Cell Biol. 2006 Jun;26(11):4327-38.

8.

A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis.

Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, Karagogeos D, Watanabe K, Dawe GS, Xiao ZC.

Nat Cell Biol. 2008 Mar;10(3):283-94. doi: 10.1038/ncb1690. Epub 2008 Feb 17. Erratum in: Nat Cell Biol. 2008 Apr;10(4):497.

PMID:
18278038
9.

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.

Cao X, S├╝dhof TC.

J Biol Chem. 2004 Jun 4;279(23):24601-11. Epub 2004 Mar 24.

10.

A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.

Hass MR, Yankner BA.

J Biol Chem. 2005 Nov 4;280(44):36895-904. Epub 2005 Aug 15.

11.

Interaction of Tau with Fe65 links tau to APP.

Barbato C, Canu N, Zambrano N, Serafino A, Minopoli G, Ciotti MT, Amadoro G, Russo T, Calissano P.

Neurobiol Dis. 2005 Mar;18(2):399-408.

PMID:
15686969
12.

Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.

Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K.

EMBO Rep. 2008 Nov;9(11):1134-40. doi: 10.1038/embor.2008.188. Epub 2008 Oct 3.

13.

Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction.

Kim SY, Kim MY, Mo JS, Park HS.

Biochim Biophys Acta. 2007 Jun;1773(6):736-46. Epub 2007 Feb 14.

14.

Dab1 binds to Fe65 and diminishes the effect of Fe65 or LRP1 on APP processing.

Kwon OY, Hwang K, Kim JA, Kim K, Kwon IC, Song HK, Jeon H.

J Cell Biochem. 2010 Oct 1;111(2):508-19. doi: 10.1002/jcb.22738.

PMID:
20568118
15.

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.

Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ.

Biochemistry. 2003 Jun 10;42(22):6664-73.

PMID:
12779321
16.

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

Pietrzik CU, Yoon IS, Jaeger S, Busse T, Weggen S, Koo EH.

J Neurosci. 2004 Apr 28;24(17):4259-65.

18.
19.

Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation.

Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T.

J Biol Chem. 2004 Jun 4;279(23):24343-54. Epub 2004 Mar 22.

20.

The FE65 proteins and Alzheimer's disease.

McLoughlin DM, Miller CC.

J Neurosci Res. 2008 Mar;86(4):744-54. Review.

PMID:
17828772

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