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Items: 1 to 20 of 304

1.

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

Boccalatte FE, Voena C, Riganti C, Bosia A, D'Amico L, Riera L, Cheng M, Ruggeri B, Jensen ON, Goss VL, Lee K, Nardone J, Rush J, Polakiewicz RD, Comb MJ, Chiarle R, Inghirami G.

Blood. 2009 Mar 19;113(12):2776-90. doi: 10.1182/blood-2008-06-161018. Epub 2008 Oct 9.

2.

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.

Ma Z, Cools J, Marynen P, Cui X, Siebert R, Gesk S, Schlegelberger B, Peeters B, De Wolf-Peeters C, Wlodarska I, Morris SW.

Blood. 2000 Mar 15;95(6):2144-9.

3.

A new variant anaplastic lymphoma kinase (ALK)-fusion protein (ATIC-ALK) in a case of ALK-positive anaplastic large cell lymphoma.

Trinei M, Lanfrancone L, Campo E, Pulford K, Mason DY, Pelicci PG, Falini B.

Cancer Res. 2000 Feb 15;60(4):793-8.

4.
6.

Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.

Christensen JG, Zou HY, Arango ME, Li Q, Lee JH, McDonnell SR, Yamazaki S, Alton GR, Mroczkowski B, Los G.

Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3314-22.

7.

Reactive oxygen species and lipoxygenases regulate the oncogenicity of NPM-ALK-positive anaplastic large cell lymphomas.

Thornber K, Colomba A, Ceccato L, Delsol G, Payrastre B, Gaits-Iacovoni F.

Oncogene. 2009 Jul 23;28(29):2690-6. doi: 10.1038/onc.2009.125. Epub 2009 Jun 8.

PMID:
19503098
8.

Tyrosine phosphorylation in human lymphomas.

Haralambieva E, Jones M, Roncador GM, Cerroni L, Lamant L, Ott G, Rosenwald A, Sherman C, Thorner P, Kusec R, Wood KM, Campo E, Falini B, Ramsay A, Marafioti T, Stein H, Kluin PM, Pulford K, Mason DY.

Histochem J. 2002;34(11-12):545-52.

PMID:
14626344
9.
10.

NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis.

McDonnell SR, Hwang SR, Basrur V, Conlon KP, Fermin D, Wey E, Murga-Zamalloa C, Zeng Z, Zu Y, Elenitoba-Johnson KS, Lim MS.

Oncogene. 2012 Aug 9;31(32):3733-40. doi: 10.1038/onc.2011.542. Epub 2011 Dec 19.

11.

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.

Kasprzycka M, Marzec M, Liu X, Zhang Q, Wasik MA.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9964-9. Epub 2006 Jun 9.

12.
13.

Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patients.

Passoni L, Longo L, Collini P, Coluccia AM, Bozzi F, Podda M, Gregorio A, Gambini C, Garaventa A, Pistoia V, Del Grosso F, Tonini GP, Cheng M, Gambacorti-Passerini C, Anichini A, Fossati-Bellani F, Di Nicola M, Luksch R.

Cancer Res. 2009 Sep 15;69(18):7338-46. doi: 10.1158/0008-5472.CAN-08-4419. Epub 2009 Sep 1.

14.
15.

Identification of NPM-ALK interacting proteins by tandem mass spectrometry.

Crockett DK, Lin Z, Elenitoba-Johnson KS, Lim MS.

Oncogene. 2004 Apr 8;23(15):2617-29.

PMID:
14968112
16.

Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation.

Chikamori M, Fujimoto J, Tokai-Nishizumi N, Yamamoto T.

Oncogene. 2007 May 3;26(20):2950-4. Epub 2006 Nov 6.

PMID:
17086210
17.

Hammerhead ribozyme-mediated cleavage of the fusion transcript NPM-ALK associated with anaplastic large-cell lymphoma.

Hübinger G, Wehnes E, Xue L, Morris SW, Maurer U.

Exp Hematol. 2003 Mar;31(3):226-33.

PMID:
12644020
18.

Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.

Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R.

Oncogene. 2004 Jul 15;23(32):5426-34.

PMID:
15184887
19.

Non-muscle myosin heavy chain (MYH9): a new partner fused to ALK in anaplastic large cell lymphoma.

Lamant L, Gascoyne RD, Duplantier MM, Armstrong F, Raghab A, Chhanabhai M, Rajcan-Separovic E, Raghab J, Delsol G, Espinos E.

Genes Chromosomes Cancer. 2003 Aug;37(4):427-32.

PMID:
12800156
20.

Molecular characterization of a new ALK translocation involving moesin (MSN-ALK) in anaplastic large cell lymphoma.

Tort F, Pinyol M, Pulford K, Roncador G, Hernandez L, Nayach I, Kluin-Nelemans HC, Kluin P, Touriol C, Delsol G, Mason D, Campo E.

Lab Invest. 2001 Mar;81(3):419-26.

PMID:
11310834

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