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Items: 1 to 20 of 138

1.

The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse.

Pirianov G, Waddington SN, Lindström TM, Terzidou V, Mehmet H, Bennett PR.

Endocrinology. 2009 Feb;150(2):699-706. doi: 10.1210/en.2008-1178. Epub 2008 Oct 9.

PMID:
18845626
2.
3.

The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour.

Sykes L, Herbert BR, Macintyre DA, Hunte E, Ponnampalam S, Johnson MR, Teoh TG, Bennett PR.

Immunology. 2013 Jul;139(3):352-65. doi: 10.1111/imm.12085.

4.

Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality.

Pirianov G, MacIntyre DA, Lee Y, Waddington SN, Terzidou V, Mehmet H, Bennett PR.

Reproduction. 2015 Oct;150(4):269-77. doi: 10.1530/REP-15-0258. Epub 2015 Jul 16.

5.

The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1.

Jung WK, Park IS, Park SJ, Yea SS, Choi YH, Oh S, Park SG, Choi IW.

Life Sci. 2009 Jul 3;85(1-2):46-53. doi: 10.1016/j.lfs.2009.04.010. Epub 2009 May 3.

PMID:
19409914
6.
7.

The 15-deoxy-δ12,14-prostaglandin J2 inhibits LPS‑stimulated inflammation via enhancement of the platelet‑activating factor acetylhydrolase activity in human retinal pigment epithelial cells.

Jung WK, Lee CM, Lee DS, Na G, Lee DY, Choi I, Park SG, Seo SK, Yang JW, Choi JS, Lee YM, Park WS, Choi IW.

Int J Mol Med. 2014 Feb;33(2):449-56. doi: 10.3892/ijmm.2013.1588. Epub 2013 Dec 13.

PMID:
24337644
8.

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

Straus DS, Pascual G, Li M, Welch JS, Ricote M, Hsiang CH, Sengchanthalangsy LL, Ghosh G, Glass CK.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4844-9.

9.
11.

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.

Cuzzocrea S, Wayman NS, Mazzon E, Dugo L, Di Paola R, Serraino I, Britti D, Chatterjee PK, Caputi AP, Thiemermann C.

Mol Pharmacol. 2002 May;61(5):997-1007.

12.

Effects of 15-deoxy-∆¹²,¹⁴-prostaglandin J₂ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide.

Kim YI, Lee JW, Lee MH, Park SW, Cho BN, Lee HK.

Mol Biol Rep. 2011 Jun;38(5):3207-12. doi: 10.1007/s11033-010-9993-5. Epub 2010 Feb 21.

PMID:
20174873
14.

Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway.

Ciucci A, Gianferretti P, Piva R, Guyot T, Snape TJ, Roberts SM, Santoro MG.

Mol Pharmacol. 2006 Nov;70(5):1812-21. Epub 2006 Aug 14.

16.

15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells.

Lee DR, Kwon CH, Park JY, Kim YK, Woo JS.

Toxicology. 2009 Apr 5;258(1):17-24. doi: 10.1016/j.tox.2009.01.001. Epub 2009 Jan 9.

PMID:
19167456
17.

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit.

Cernuda-Morollón E, Pineda-Molina E, Cañada FJ, Pérez-Sala D.

J Biol Chem. 2001 Sep 21;276(38):35530-6. Epub 2001 Jul 20.

19.

Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.

Sánchez-Gómez FJ, Cernuda-Morollón E, Stamatakis K, Pérez-Sala D.

Mol Pharmacol. 2004 Nov;66(5):1349-58. Epub 2004 Aug 18.

20.

Glutathione prevents preterm parturition and fetal death by targeting macrophage-induced reactive oxygen species production in the myometrium.

Hadi T, Bardou M, Mace G, Sicard P, Wendremaire M, Barrichon M, Richaud S, Demidov O, Sagot P, Garrido C, Lirussi F.

FASEB J. 2015 Jun;29(6):2653-66. doi: 10.1096/fj.14-266783. Epub 2015 Mar 10.

PMID:
25757563

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