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Items: 1 to 20 of 194

1.

X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.

Saito Y, Sano Y, Vassar R, Gandy S, Nakaya T, Yamamoto T, Suzuki T.

J Biol Chem. 2008 Dec 19;283(51):35763-71. doi: 10.1074/jbc.M801353200. Epub 2008 Oct 9.

2.

Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain.

Sano Y, Syuzo-Takabatake A, Nakaya T, Saito Y, Tomita S, Itohara S, Suzuki T.

J Biol Chem. 2006 Dec 8;281(49):37853-60. Epub 2006 Oct 10.

3.

Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like.

Saito Y, Akiyama M, Araki Y, Sumioka A, Shiono M, Taru H, Nakaya T, Yamamoto T, Suzuki T.

PLoS One. 2011;6(7):e22108. doi: 10.1371/journal.pone.0022108. Epub 2011 Jul 19.

4.

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.

Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T.

J Biol Chem. 2003 Dec 5;278(49):49448-58. Epub 2003 Sep 12.

5.

Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.

Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.

Eur J Neurosci. 2013 Jun;37(12):1962-9. doi: 10.1111/ejn.12235.

PMID:
23773065
7.

Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.

Ho A, Liu X, Südhof TC.

J Neurosci. 2008 Dec 31;28(53):14392-400. doi: 10.1523/JNEUROSCI.2481-08.2008.

8.

The X11 proteins, Abeta production and Alzheimer's disease.

Miller CC, McLoughlin DM, Lau KF, Tennant ME, Rogelj B.

Trends Neurosci. 2006 May;29(5):280-5. Epub 2006 Mar 20. Review.

PMID:
16545469
9.

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.

Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE.

J Biol Chem. 2009 May 1;284(18):11863-72. doi: 10.1074/jbc.M807345200. Epub 2009 Feb 27.

10.

Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage.

Takei N, Sobu Y, Kimura A, Urano S, Piao Y, Araki Y, Taru H, Yamamoto T, Hata S, Nakaya T, Suzuki T.

J Biol Chem. 2015 Jan 9;290(2):987-95. doi: 10.1074/jbc.M114.599852. Epub 2014 Nov 18.

11.

Expression and localization of X11 family proteins in neurons.

Motodate R, Saito Y, Hata S, Suzuki T.

Brain Res. 2016 Sep 1;1646:227-234. doi: 10.1016/j.brainres.2016.05.054. Epub 2016 Jun 4.

PMID:
27268412
12.

Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism.

Ho CS, Marinescu V, Steinhilb ML, Gaut JR, Turner RS, Stuenkel EL.

J Biol Chem. 2002 Jul 26;277(30):27021-8. Epub 2002 May 16.

13.

Reduction of β-amyloid accumulation by reticulon 3 in transgenic mice.

Araki W, Oda A, Motoki K, Hattori K, Itoh M, Yuasa S, Konishi Y, Shin RW, Tamaoka A, Ogino K.

Curr Alzheimer Res. 2013 Feb;10(2):135-42.

PMID:
22742855
14.

Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation.

Sullivan SE, Dillon GM, Sullivan JM, Ho A.

J Biol Chem. 2014 May 30;289(22):15374-83. doi: 10.1074/jbc.M113.541003. Epub 2014 Apr 17.

15.

Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.

Sakuma M, Tanaka E, Taru H, Tomita S, Gandy S, Nairn AC, Nakaya T, Yamamoto T, Suzuki T.

J Neurochem. 2009 Apr;109(2):465-75. doi: 10.1111/j.1471-4159.2009.05988.x. Epub 2009 Feb 13.

16.

Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila.

Gross GG, Feldman RM, Ganguly A, Wang J, Yu H, Guo M.

PLoS One. 2008 Jun 25;3(6):e2495. doi: 10.1371/journal.pone.0002495.

17.
18.

The X11/Mint family of adaptor proteins.

Rogelj B, Mitchell JC, Miller CC, McLoughlin DM.

Brain Res Rev. 2006 Sep;52(2):305-15. Epub 2006 Jun 9. Review.

PMID:
16764936
19.
20.

Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.

Sakurai T, Kaneko K, Okuno M, Wada K, Kashiyama T, Shimizu H, Akagi T, Hashikawa T, Nukina N.

J Cell Biol. 2008 Oct 20;183(2):339-52. doi: 10.1083/jcb.200804075.

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