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Items: 1 to 20 of 236

1.

Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2.

Hinson SR, Roemer SF, Lucchinetti CF, Fryer JP, Kryzer TJ, Chamberlain JL, Howe CL, Pittock SJ, Lennon VA.

J Exp Med. 2008 Oct 27;205(11):2473-81. doi: 10.1084/jem.20081241. Epub 2008 Oct 6.

2.

Neurological autoimmunity targeting aquaporin-4.

Hinson SR, McKeon A, Lennon VA.

Neuroscience. 2010 Jul 28;168(4):1009-18. doi: 10.1016/j.neuroscience.2009.08.032. Epub 2009 Aug 20. Review.

PMID:
19699271
3.

Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica.

Ratelade J, Bennett JL, Verkman AS.

J Biol Chem. 2011 Dec 30;286(52):45156-64. doi: 10.1074/jbc.M111.297275. Epub 2011 Nov 8.

4.

Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis.

Roemer SF, Parisi JE, Lennon VA, Benarroch EE, Lassmann H, Bruck W, Mandler RN, Weinshenker BG, Pittock SJ, Wingerchuk DM, Lucchinetti CF.

Brain. 2007 May;130(Pt 5):1194-205. Epub 2007 Feb 4.

PMID:
17282996
5.

Neuromyelitis optica study model based on chronic infusion of autoantibodies in rat cerebrospinal fluid.

Marignier R, Ruiz A, Cavagna S, Nicole A, Watrin C, Touret M, Parrot S, Malleret G, Peyron C, Benetollo C, Auvergnon N, Vukusic S, Giraudon P.

J Neuroinflammation. 2016 May 18;13(1):111. doi: 10.1186/s12974-016-0577-8.

6.

Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays.

Iorio R, Fryer JP, Hinson SR, Fallier-Becker P, Wolburg H, Pittock SJ, Lennon VA.

J Autoimmun. 2013 Feb;40:21-7. doi: 10.1016/j.jaut.2012.07.008. Epub 2012 Aug 18.

7.

Neuromyelitis Optica Immunoglobulin G present in sera from neuromyelitis optica patients affects aquaporin-4 expression and water permeability of the astrocyte plasma membrane.

Melamud L, Fernández JM, Rivarola V, Di Giusto G, Ford P, Villa A, Capurro C.

J Neurosci Res. 2012 Jun;90(6):1240-8. doi: 10.1002/jnr.22822. Epub 2012 Feb 22.

PMID:
22354518
8.

Optic neuritis in neuromyelitis optica.

Levin MH, Bennett JL, Verkman AS.

Prog Retin Eye Res. 2013 Sep;36:159-71. doi: 10.1016/j.preteyeres.2013.03.001. Epub 2013 Mar 30.

9.

Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica.

Hinson SR, Pittock SJ, Lucchinetti CF, Roemer SF, Fryer JP, Kryzer TJ, Lennon VA.

Neurology. 2007 Dec 11;69(24):2221-31. Epub 2007 Oct 10.

PMID:
17928579
10.

Aquaporin-4 antibodies, CNS acidosis and neuromyelitis optica: a potential link.

Jarius S, Wildemann B.

Med Hypotheses. 2013 Dec;81(6):1090-5. doi: 10.1016/j.mehy.2013.10.011. Epub 2013 Oct 16.

PMID:
24182872
11.

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes.

Hinson SR, Romero MF, Popescu BF, Lucchinetti CF, Fryer JP, Wolburg H, Fallier-Becker P, Noell S, Lennon VA.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1245-50. doi: 10.1073/pnas.1109980108. Epub 2011 Nov 29.

12.

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.

Marignier R, Nicolle A, Watrin C, Touret M, Cavagna S, Varrin-Doyer M, Cavillon G, Rogemond V, Confavreux C, Honnorat J, Giraudon P.

Brain. 2010 Sep;133(9):2578-91. doi: 10.1093/brain/awq177. Epub 2010 Aug 5.

PMID:
20688809
13.

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms.

Zhang H, Bennett JL, Verkman AS.

Ann Neurol. 2011 Dec;70(6):943-54. doi: 10.1002/ana.22551. Epub 2011 Nov 8.

14.

[Recent progress in multiple sclerosis research: astrocytopathy in demyelinating diseases].

Kira J.

Rinsho Shinkeigaku. 2010 Nov;50(11):788-93. Review. Japanese.

PMID:
21921443
15.

The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model.

Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, Holmoy T, Misu T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV.

Exp Neurol. 2015 Mar;265:8-21. doi: 10.1016/j.expneurol.2014.12.015. Epub 2014 Dec 24.

16.

Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodies.

Nicchia GP, Mastrototaro M, Rossi A, Pisani F, Tortorella C, Ruggieri M, Lia A, Trojano M, Frigeri A, Svelto M.

Glia. 2009 Oct;57(13):1363-73. doi: 10.1002/glia.20855.

PMID:
19229993
17.

The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica.

Lucchinetti CF, Guo Y, Popescu BF, Fujihara K, Itoyama Y, Misu T.

Brain Pathol. 2014 Jan;24(1):83-97. doi: 10.1111/bpa.12099. Review.

18.

Human immunoglobulin G reduces the pathogenicity of aquaporin-4 autoantibodies in neuromyelitis optica.

Ratelade J, Smith AJ, Verkman AS.

Exp Neurol. 2014 May;255:145-53. doi: 10.1016/j.expneurol.2014.03.004. Epub 2014 Mar 14.

19.

Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies.

Ratelade J, Verkman AS.

Int J Biochem Cell Biol. 2012 Sep;44(9):1519-30. doi: 10.1016/j.biocel.2012.06.013. Epub 2012 Jun 17. Review.

20.

Prediction of neuromyelitis optica attack severity by quantitation of complement-mediated injury to aquaporin-4-expressing cells.

Hinson SR, McKeon A, Fryer JP, Apiwattanakul M, Lennon VA, Pittock SJ.

Arch Neurol. 2009 Sep;66(9):1164-7. doi: 10.1001/archneurol.2009.188.

PMID:
19752309

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