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Items: 1 to 20 of 122

1.

Activation and translocation of glucokinase in rat primary hepatocytes monitored by high content image analysis.

Wolff M, Kauschke SG, Schmidt S, Heilker R.

J Biomol Screen. 2008 Oct;13(9):837-46. doi: 10.1177/1087057108323910. Epub 2008 Sep 23.

PMID:
18812575
2.

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.

Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y.

J Biol Chem. 2006 Dec 8;281(49):37668-74. Epub 2006 Oct 6.

3.

Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Mukhtar MH, Payne VA, Arden C, Harbottle A, Khan S, Lange AJ, Agius L.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R766-74. doi: 10.1152/ajpregu.00593.2007. Epub 2008 Jan 16.

PMID:
18199594
4.

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.

Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14511-6.

5.

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.

Brocklehurst KJ, Payne VA, Davies RA, Carroll D, Vertigan HL, Wightman HJ, Aiston S, Waddell ID, Leighton B, Coghlan MP, Agius L.

Diabetes. 2004 Mar;53(3):535-41.

6.

Regulation of hepatic glucose metabolism by translocation of glucokinase between the nucleus and the cytoplasm in hepatocytes.

Toyoda Y, Tsuchida A, Iwami E, Shironoguchi H, Miwa I.

Horm Metab Res. 2001 Jun;33(6):329-36.

PMID:
11456280
8.

Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis.

Bourbonais FJ, Chen J, Huang C, Zhang Y, Pfefferkorn JA, Landro JA.

Biochem J. 2012 Feb 1;441(3):881-7. doi: 10.1042/BJ20110721.

PMID:
22044397
9.
10.

Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.

de la Iglesia N, Veiga-da-Cunha M, Van Schaftingen E, Guinovart JJ, Ferrer JC.

FEBS Lett. 1999 Aug 6;456(2):332-8.

11.

Intracellular distribution of hepatic glucokinase and glucokinase regulatory protein during the fasted to refed transition in rats.

Fernández-Novell JM, Castel S, Bellido D, Ferrer JC, Vilaró S, Guinovart JJ.

FEBS Lett. 1999 Oct 8;459(2):211-4.

12.
15.

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations.

Heredia VV, Carlson TJ, Garcia E, Sun S.

J Biol Chem. 2006 Dec 29;281(52):40201-7. Epub 2006 Nov 2.

16.

Glucokinase and glucokinase regulatory proteins are functionally coexpressed before birth in the rat brain.

Roncero I, Sanz C, Alvarez E, Vázquez P, Barrio PA, Blázquez E.

J Neuroendocrinol. 2009 Dec;21(12):973-81. doi: 10.1111/j.1365-2826.2009.01919.x. Epub 2009 Oct 6.

PMID:
19807849
17.

Glucokinase regulatory protein may interact with glucokinase in the hepatocyte nucleus.

Brown KS, Kalinowski SS, Megill JR, Durham SK, Mookhtiar KA.

Diabetes. 1997 Feb;46(2):179-86.

PMID:
9000692
18.
19.

Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats.

Payne VA, Arden C, Lange AJ, Agius L.

Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R618-25. Epub 2007 Jun 6.

PMID:
17553851
20.

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