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Items: 1 to 20 of 83

1.

Immunohistochemical evidence of ubiquitous distribution of the metalloendoprotease insulin-degrading enzyme (IDE; insulysin) in human non-malignant tissues and tumor cell lines.

Weirich G, Mengele K, Yfanti C, Gkazepis A, Hellmann D, Welk A, Giersig C, Kuo WL, Rosner MR, Tang WJ, Schmitt M.

Biol Chem. 2008 Nov;389(11):1441-5. doi: 10.1515/BC.2008.157.

2.

Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues.

Yfanti C, Mengele K, Gkazepis A, Weirich G, Giersig C, Kuo WL, Tang WJ, Rosner M, Schmitt M.

Int J Mol Med. 2008 Oct;22(4):421-31.

3.

Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues.

Kuo WL, Montag AG, Rosner MR.

Endocrinology. 1993 Feb;132(2):604-11.

PMID:
7678795
4.

Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels.

Radulescu RT, Hufnagel C, Luppa P, Hellebrand H, Kuo WL, Rosner MR, Harbeck N, Giersig C, Meindl A, Schmitt M, Weirich G.

Int J Oncol. 2007 Jan;30(1):73-80.

PMID:
17143514
5.

Modulation of insulin degrading enzyme activity and liver cell proliferation.

Pivovarova O, von Loeffelholz C, Ilkavets I, Sticht C, Zhuk S, Murahovschi V, Lukowski S, Döcke S, Kriebel J, de las Heras Gala T, Malashicheva A, Kostareva A, Lock JF, Stockmann M, Grallert H, Gretz N, Dooley S, Pfeiffer AF, Rudovich N.

Cell Cycle. 2015;14(14):2293-300. doi: 10.1080/15384101.2015.1046647. Epub 2015 May 6.

6.

Natural regulatory mechanisms of insulin degradation by insulin degrading enzyme.

Akiyama H, Yokono K, Shii K, Ogawa W, Taniguchi H, Baba S, Kasuga M.

Biochem Biophys Res Commun. 1990 Aug 16;170(3):1325-30.

PMID:
2202301
7.

Insulin-degrading enzyme (IDE): a novel heat shock-like protein.

Tundo GR, Sbardella D, Ciaccio C, Bianculli A, Orlandi A, Desimio MG, Arcuri G, Coletta M, Marini S.

J Biol Chem. 2013 Jan 25;288(4):2281-9. doi: 10.1074/jbc.M112.393108. Epub 2012 Nov 27.

8.

Glucose inhibits the insulin-induced activation of the insulin-degrading enzyme in HepG2 cells.

Pivovarova O, Gögebakan O, Pfeiffer AF, Rudovich N.

Diabetologia. 2009 Aug;52(8):1656-64. doi: 10.1007/s00125-009-1350-7. Epub 2009 Apr 25.

PMID:
19396426
9.

Insulin-degrading enzyme in a human colon adenocarcinoma cell line (Caco-2).

Bai JP, Hsu MJ, Shier WT.

Pharm Res. 1995 Apr;12(4):513-7.

PMID:
7596985
10.

Immunochemical studies on the insulin-degrading enzyme from pig and rat skeletal muscle.

Yokono K, Imamura Y, Shii K, Mizuno N, Sakai H, Baba S.

Diabetes. 1980 Oct;29(10):856-9.

PMID:
6777221
11.

Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.

Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ.

Biochemistry. 2005 May 3;44(17):6513-25.

PMID:
15850385
12.

Regulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese mice.

Wei X, Ke B, Zhao Z, Ye X, Gao Z, Ye J.

PLoS One. 2014 Apr 16;9(4):e95399. doi: 10.1371/journal.pone.0095399. eCollection 2014.

13.

Reduced neuronal expression of insulin-degrading enzyme in the dorsolateral prefrontal cortex of patients with haloperidol-treated, chronic schizophrenia.

Bernstein HG, Ernst T, Lendeckel U, Bukowska A, Ansorge S, Stauch R, Have ST, Steiner J, Dobrowolny H, Bogerts B.

J Psychiatr Res. 2009 Sep;43(13):1095-105. doi: 10.1016/j.jpsychires.2009.03.006. Epub 2009 Apr 23.

PMID:
19394958
14.

Androgen- and estrogen-dependent regulation of insulin-degrading enzyme in subcellular fractions of rat prostate and uterus.

Udrisar DP, Wanderley MI, Porto RC, Cardoso CL, Barbosa MC, Camberos MC, Cresto JC.

Exp Biol Med (Maywood). 2005 Jul;230(7):479-86.

PMID:
15985623
15.

Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster.

Stoppelli MP, Garcia JV, Decker SJ, Rosner MR.

Proc Natl Acad Sci U S A. 1988 May;85(10):3469-73.

16.

Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver.

Ogawa W, Shii K, Yonezawa K, Baba S, Yokono K.

J Biol Chem. 1992 Jan 15;267(2):1310-6.

17.

Regulation of protein degradation by insulin-degrading enzyme: analysis by small interfering RNA-mediated gene silencing.

Fawcett J, Permana PA, Levy JL, Duckworth WC.

Arch Biochem Biophys. 2007 Dec 1;468(1):128-33. Epub 2007 Sep 29. Erratum in: Arch Biochem Biophys. 2008 May 1;473(1):96.

PMID:
17964527
18.

Cellular localization of insulin-degrading enzyme in rat liver using monoclonal antibodies specific for this enzyme.

Akiyama H, Shii K, Yokono K, Yonezawa K, Sato S, Watanabe K, Baba S.

Biochem Biophys Res Commun. 1988 Sep 15;155(2):914-22.

PMID:
3048264
19.

Immunohistochemical localization of insulin-degrading enzyme along the rat intestine, in the human colon adenocarcinoma cell line (Caco-2), and in human ileum.

Chang LL, Stout LE, Wong WD, Buls JG, Rothenberger DA, Shier WT, Sorenson RL, Bai JP.

J Pharm Sci. 1997 Jan;86(1):116-9.

PMID:
9002470

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