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Items: 1 to 20 of 1278

1.

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.

BMC Cancer. 2008 Sep 9;8:255. doi: 10.1186/1471-2407-8-255.

2.

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.

Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S Jr.

Oncogene. 2005 Nov 17;24(51):7630-4.

PMID:
16007118
3.
4.

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Kambara T, Simms LA, Whitehall VL, Spring KJ, Wynter CV, Walsh MD, Barker MA, Arnold S, McGivern A, Matsubara N, Tanaka N, Higuchi T, Young J, Jass JR, Leggett BA.

Gut. 2004 Aug;53(8):1137-44.

5.
6.

Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.

Kim KM, Lee EJ, Ha S, Kang SY, Jang KT, Park CK, Kim JY, Kim YH, Chang DK, Odze RD.

Am J Surg Pathol. 2011 Sep;35(9):1274-86. doi: 10.1097/PAS.0b013e318224cd2e.

PMID:
21836485
7.

Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women.

Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ.

Gastroenterology. 2013 Aug;145(2):348-56.e1-2. doi: 10.1053/j.gastro.2013.05.001. Epub 2013 May 7.

8.

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

Goel A, Nagasaka T, Arnold CN, Inoue T, Hamilton C, Niedzwiecki D, Compton C, Mayer RJ, Goldberg R, Bertagnolli MM, Boland CR.

Gastroenterology. 2007 Jan;132(1):127-38. Epub 2006 Sep 20.

PMID:
17087942
9.

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.

Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R.

J Pathol. 2008 Feb;214(3):320-7.

PMID:
18098337
10.

Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.

Kim YH, Kakar S, Cun L, Deng G, Kim YS.

Int J Cancer. 2008 Dec 1;123(11):2587-93. doi: 10.1002/ijc.23840.

11.

The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.

Renaud F, Mariette C, Vincent A, Wacrenier A, Maunoury V, Leclerc J, Coppin L, Crépin M, Van Seuningen I, Leteurtre E, Buisine MP.

Int J Cancer. 2016 Mar 15;138(6):1472-81. doi: 10.1002/ijc.29891. Epub 2015 Oct 30.

12.

Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.

Lee S, Cho NY, Choi M, Yoo EJ, Kim JH, Kang GH.

Pathol Int. 2008 Feb;58(2):104-13. doi: 10.1111/j.1440-1827.2007.02197.x.

PMID:
18199160
13.

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.

Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S Jr, Carneiro F, Seruca R.

Oncogene. 2007 Jan 4;26(1):158-63. Epub 2006 Sep 4.

PMID:
16953233
14.

[Colorectal serrated lesions: current insight on their role in colorectal carcinogenesis].

Mäkinen M.

Duodecim. 2010;126(17):2002-11. Review. Finnish.

PMID:
21053517
15.

Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.

Ogino S, Kawasaki T, Ogawa A, Kirkner GJ, Loda M, Fuchs CS.

Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.

PMID:
17350669
16.

KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy.

Yamane LS, Scapulatempo-Neto C, Alvarenga L, Oliveira CZ, Berardinelli GN, Almodova E, Cunha TR, Fava G, Colaiacovo W, Melani A, Fregnani JH, Reis RM, Guimarães DP.

Oncol Rep. 2014 Oct;32(4):1419-26. doi: 10.3892/or.2014.3338. Epub 2014 Jul 18.

PMID:
25050586
17.

Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.

García-Solano J, Conesa-Zamora P, Carbonell P, Trujillo-Santos J, Torres-Moreno D D, Pagán-Gómez I, Rodríguez-Braun E, Pérez-Guillermo M.

Int J Cancer. 2012 Oct 15;131(8):1790-9. doi: 10.1002/ijc.27454. Epub 2012 Mar 14.

18.

BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.

Chan TL, Zhao W, Leung SY, Yuen ST; Cancer Genome Project..

Cancer Res. 2003 Aug 15;63(16):4878-81.

19.

Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.

Kriegl L, Neumann J, Vieth M, Greten FR, Reu S, Jung A, Kirchner T.

Mod Pathol. 2011 Jul;24(7):1015-22. doi: 10.1038/modpathol.2011.43. Epub 2011 Mar 18.

20.

Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability.

Kakar S, Deng G, Sahai V, Matsuzaki K, Tanaka H, Miura S, Kim YS.

Arch Pathol Lab Med. 2008 Jun;132(6):958-64. doi: 10.1043/1543-2165(2008)132[958:CCCIMP]2.0.CO;2.

PMID:
18517279

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