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Items: 1 to 20 of 88

1.

Assessing siRNA pharmacodynamics in a luciferase-expressing mouse.

Svensson RU, Shey MR, Ballas ZK, Dorkin JR, Goldberg M, Akinc A, Langer R, Anderson DG, Bumcrot D, Henry MD.

Mol Ther. 2008 Dec;16(12):1995-2001. doi: 10.1038/mt.2008.187. Epub 2008 Sep 9.

2.

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels.

Hassani Z, Lemkine GF, Erbacher P, Palmier K, Alfama G, Giovannangeli C, Behr JP, Demeneix BA.

J Gene Med. 2005 Feb;7(2):198-207.

PMID:
15515135
3.
4.

Usefulness of the luciferase reporter system to test the efficacy of siRNA.

Zhuang F, Liu YH.

Methods Mol Biol. 2006;342:181-7. Review.

PMID:
16957375
5.

Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I.

Kim SI, Shin D, Choi TH, Lee JC, Cheon GJ, Kim KY, Park M, Kim M.

Mol Ther. 2007 Jun;15(6):1145-52. Epub 2007 Apr 17.

6.

Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model.

Wang Q, Ilves H, Chu P, Contag CH, Leake D, Johnston BH, Kaspar RL.

J Invest Dermatol. 2007 Nov;127(11):2577-84. Epub 2007 May 24.

7.

Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles.

Li SD, Chono S, Huang L.

J Control Release. 2008 Feb 18;126(1):77-84. Epub 2007 Nov 17.

8.

Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination.

Safran M, Kim WY, Kung AL, Horner JW, DePinho RA, Kaelin WG Jr.

Mol Imaging. 2003 Oct;2(4):297-302.

PMID:
14717328
9.

Early-stage development of novel cyclodextrin-siRNA nanocomplexes allows for successful postnebulization transfection of bronchial epithelial cells.

Hibbitts A, O'Mahony AM, Forde E, Nolan L, Ogier J, Desgranges S, Darcy R, MacLoughlin R, O'Driscoll CM, Cryan SA.

J Aerosol Med Pulm Drug Deliv. 2014 Dec;27(6):466-77. doi: 10.1089/jamp.2013.1045.

PMID:
24665866
10.

A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells.

Hung CF, Lu KC, Cheng TL, Wu RH, Huang LY, Teng CF, Chang WT.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):707-20. Epub 2006 Jun 5.

PMID:
16793020
11.

Establishment of evaluation method for siRNA delivery using stable cell line carrying the luciferase reporter gene.

Iijima A, Hachisu R, Kobayashi H, Hashimoto K, Asano D, Kikuchi H.

Biol Pharm Bull. 2007 Oct;30(10):1844-50.

12.

Control of siRNA expression using the Cre-loxP recombination system.

Kasim V, Miyagishi M, Taira K.

Nucleic Acids Res. 2004 Apr 23;32(7):e66.

13.

siRNA delivery to lung-metastasized tumor by systemic injection with cationic liposomes.

Hattori Y, Nakamura A, Arai S, Kawano K, Maitani Y, Yonemochi E.

J Liposome Res. 2015;25(4):279-86. doi: 10.3109/08982104.2014.992024. Epub 2015 Sep 4.

PMID:
25543847
14.

Conditional bicistronic Cre reporter line expressing both firefly luciferase and β-galactosidase.

Ishikawa TO, Herschman HR.

Mol Imaging Biol. 2011 Apr;13(2):284-92. doi: 10.1007/s11307-010-0333-x.

15.

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation.

Hegde V, Hickerson RP, Nainamalai S, Campbell PA, Smith FJ, McLean WH, Pedrioli DM.

J Control Release. 2014 Dec 28;196:355-62. doi: 10.1016/j.jconrel.2014.10.022. Epub 2014 Oct 30.

16.

siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model.

Gonzalez-Gonzalez E, Ra H, Hickerson RP, Wang Q, Piyawattanametha W, Mandella MJ, Kino GS, Leake D, Avilion AA, Solgaard O, Doyle TC, Contag CH, Kaspar RL.

Gene Ther. 2009 Aug;16(8):963-72. doi: 10.1038/gt.2009.62. Epub 2009 May 28.

PMID:
19474811
17.

Characterization of long-circulating cationic nanoparticle formulations consisting of a two-stage PEGylation step for the delivery of siRNA in a breast cancer tumor model.

Ho EA, Osooly M, Strutt D, Masin D, Yang Y, Yan H, Bally M.

J Pharm Sci. 2013 Jan;102(1):227-36. doi: 10.1002/jps.23351. Epub 2012 Nov 6.

PMID:
23132529
18.

Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery.

Malamas AS, Gujrati M, Kummitha CM, Xu R, Lu ZR.

J Control Release. 2013 Nov 10;171(3):296-307. doi: 10.1016/j.jconrel.2013.06.019. Epub 2013 Jun 21.

19.

Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.

Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L.

Mol Ther. 2010 Sep;18(9):1657-66. doi: 10.1038/mt.2010.147. Epub 2010 Jul 13.

20.

[An efficient method for screening effective siRNAs using dual-luciferase reporter assay system].

Shan ZX, Lin QX, Tan HH, Deng CY, Liu XY, Xiao DZ, Yu XY.

Nan Fang Yi Ke Da Xue Xue Bao. 2009 Aug;29(8):1577-81. Chinese.

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